Results 221 to 230 of about 455,452 (370)

Lipoprotein lipase activity is required for cardiac lipid droplet production[S]

open access: yesJournal of Lipid Research, 2014
The rodent heart accumulates TGs and lipid droplets during fasting. The sources of heart lipids could be either FFAs liberated from adipose tissue or FAs from lipoprotein-associated TGs via the action of lipoprotein lipase (LpL).
Chad M. Trent   +6 more
doaj  

The role of Moringa oleifera in the development of alternative biofuels, under the concept of an integral one‐tree biorefinery: A minireview

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract The Moringa oleifera oil tree is commonly known as the ‘tree of life’ or the ‘miracle tree’ owing to its multiple benefits for humans. The different parts that make up this tree (leaves, seeds and bark) have been used to treat various ailments, diseases and wounds. However, in recent years this tree is being used by the scientific community to
J. L. Aleman‐Ramirez   +4 more
wiley   +1 more source

DGAT1 deficiency decreases PPAR expression and does not lead to lipotoxicity in cardiac and skeletal muscle[S]

open access: yesJournal of Lipid Research, 2011
Diacylglycerol (DAG) acyl transferase 1 (Dgat1) knockout (−/−) mice are resistant to high-fat-induced obesity and insulin resistance, but the reasons are unclear.
Li Liu   +13 more
doaj  

Safety, tolerability, pharmacokinetics and pharmacodynamics of HSK31858, a novel oral dipeptidyl peptidase‐1 inhibitor, in healthy volunteers: An integrated phase 1, randomized, double‐blind, placebo‐controlled, single‐ and multiple‐ascending dose study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Dipeptidyl peptidase‐1 (DPP‐1) inhibitors have been studied for the treatment of neutrophil‐mediated inflammatory diseases including bronchiectasis, bronchial asthma and cystic fibrosis. This study evaluated the pharmacokinetics, pharmacodynamics, safety and tolerability of DPP‐1 inhibitor HSK31858 in healthy Chinese volunteers.
Yuhao Wang   +7 more
wiley   +1 more source

Implementing physician‐led medication reviews for patients with diabetes and severe mental disorder: A randomized controlled trial

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Patients with severe mental disorder and diabetes may be exposed to inappropriate polypharmacy increasing the risk of side effects and drug interactions. Although medication reviews may facilitate short‐term deprescribing, they are not known to affect clinical outcomes.
Johan Frederik Mebus Meyer Christensen   +2 more
wiley   +1 more source

Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application

open access: yesBMEMat, EarlyView.
The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy