Results 171 to 180 of about 674,554 (406)

Decoding Blastocystis‐Driven Mechanisms in Gut Microbiota and Host Metabolism

open access: yesAdvanced Science, EarlyView.
Blastocystis, a prevalent gut microbe, interacts with the host through metabolic and immune pathways, influencing cardiometabolic health. This perspective explores its role in modulating short‐chain fatty acid production, tryptophan metabolism, and immune signaling, potentially impacting cholesterol absorption, glucose metabolism, and vascular health ...
Lei Deng, Kevin SW Tan
wiley   +1 more source

Health Information and Social Security Entitlements [PDF]

open access: yes, 2013
This study examines whether new health information, obtained through medical screening, affects entitlements to Social Security benefits. Random assignment of information is derived from a unique feature of the Continuous National Health and Nutrition ...
Perry Singleton
core   +1 more source

ISG15 Enhances the Activity of γ‐Glutamate Cysteine Ligase to Suppress Apoptosis in High Fat Diet‐Promoted Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
Hepatocellular carcinoma (HCC) cells under high‐fat environment constrain harmful reactive oxygen species (ROS) by enhancing glutathione synthesis though upregulating interferon stimulated gene 15 (ISG15). In this process, upregulated high mobility group A1 (HMGA1) enhances ISG15 transcription, upregulated ISG15 subsequently noncovalently binds with ...
Xinran Liu   +21 more
wiley   +1 more source

Effect of effective microorganisms on some biochemical parameters in broiler chicks [PDF]

open access: yesIraqi Journal of Veterinary Sciences, 2014
This study was conducted to investigate the potential effect of effective microorganisms (EM) on some biochemical parameters which includes; glucose, cholesterol and triglycerides levels in addition to the levels of Alanine aminotransferase (ALT) and ...
S.K. Abd
doaj  

Secondary Phenotype Analysis in Ascertained Family Designs: Application to the Leiden Longevity Study [PDF]

open access: yesarXiv, 2016
The case-control design is often used to test associations between the case-control status and genetic variants. In addition to this primary phenotype a number of additional traits, known as secondary phenotypes, are routinely recorded and typically associations between genetic factors and these secondary traits are studied too.
arxiv  

MTCH2 Suppresses Thermogenesis by Regulating Autophagy in Adipose Tissue

open access: yesAdvanced Science, EarlyView.
This study demonstrates that MTCH2 acts as an evolutionarily conserved regulator of energy homeostasis across Drosophila, rodents, and humans. Adipose‐specific MTCH2 ablation enhances brown/beige adipose thermogenesis through Bcl‐2‐dependent autophagy, promoting energy expenditure and counteracting obesity‐associated metabolic disorders. These findings
Xin‐Yuan Zhao   +17 more
wiley   +1 more source

Central lipid detection and the regulation of feeding behavior

open access: yesOléagineux, Corps gras, Lipides, 2013
The modern abundance of energy-rich foods combined with a shift to more sedentary lifestyles has led to a thermodynamic imbalance in which excessive caloric intake and reduced energy expenditure account for the prevalence of obesity.
Cansell Céline, Luquet Serge
doaj   +1 more source

Enhancing Metabolic Syndrome Prediction with Hybrid Data Balancing and Counterfactuals [PDF]

open access: yesarXiv
Metabolic Syndrome (MetS) is a cluster of interrelated risk factors that significantly increases the risk of cardiovascular diseases and type 2 diabetes. Despite its global prevalence, accurate prediction of MetS remains challenging due to issues such as class imbalance, data scarcity, and methodological inconsistencies in existing studies.
arxiv  

High-dimensional confounding adjustment using continuous spike and slab priors [PDF]

open access: yesarXiv, 2017
In observational studies, estimation of a causal effect of a treatment on an outcome relies on proper adjustment for confounding. If the number of the potential confounders ($p$) is larger than the number of observations ($n$), then direct control for all potential confounders is infeasible.
arxiv  

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