Results 171 to 180 of about 704,019 (386)

Hepatic CBP/p300 Orchestrate Amino Acid‐Driven Gluconeogenesis through Histone Crotonylation

Advanced Science, EarlyView.
Hepatic CBP/p300 control amino acid‐driven gluconeogenesis by modulating histone crotonylation. This study identifies 2‐aminoadipate (2‐AAA) as a key metabolite that enhances crotonylation and activates amino acid and gluconeogenic gene expression.
Chunxiang Sheng, Tianjiao Li, Hong Lin, Xiaoqin Ma, Feiye Zhou, Mingzhu Li, Yiru Wang, Shushu Wang, Jialin Tan, Junmin Chen, Yulin Yang, Jianmin Liu, Yufang Bi, Jieli Lu, Xiao Wang, Libin Zhou   +15 more
wiley   +1 more source

Efecto del ácido linoleico conjugado (CLA) sobre el perfil lipídico en humanos

Archivos Latinoamericanos de Nutrición
El término ácido linoleico conjugado (CLA) hace referencia a un grupo de isómeros del ácido linoleico, caracterizados por tener enlaces dobles conjugados en varias posiciones y conformaciones.
Mayi Agueda, María Ángeles Zulet, José Alfredo Martínez   +2 more
doaj  

Prognostic Value of Normal Triglyceride Levels among Patients with Target Low-density Lipoproteins Presenting with First Acute Coronary Syndrome

Heart Views
Introduction: Hypercholesterolemia, mainly low-density lipoprotein cholesterol (LDL-C) and triglycerides (TGs), is a major risk factor for coronary artery disease (CAD).
Ahmed Aljizeeri, Abdulkareem M Aloqbawi, Fahad Mohammed Albaqami, Mohammed Hamad Alhelal, Mohammed K. Altoyan, Faisal A. Bin Talib, Amjad Ahmed, Alwaleed Altuwaijri, Ahmed Alsahhaf, Waleed Aljasser, Nawaf Ziyad Alotaibi, Abdullah Moteb Albaz, Abdulaziz Algethami, Ahmed Alsaileek   +13 more
doaj   +1 more source

Kidney triglyceride accumulation in the fasted mouse is dependent upon serum free fatty acids [PDF]

, 2017
Abumrad, Nada A., al, et, Cifarelli, Vincenza   +2 more
core   +2 more sources

Lipid‐Based Nanoparticles in Cancer Therapy: Advances in Targeted Drug Delivery and Therapeutic Potential for Renal Cell Carcinoma

Advanced Science, EarlyView.
This review explores the transformative potential of lipid‐based nanoparticles (LNPs) in renal cell carcinoma (RCC) therapy. It systematically analyzes six LNP platforms‐from liposomes to hybrid nanoparticles‐highlighting their unique advantages in targeted drug delivery, resistance reversal, and immunomodulation.
Wei Yao, Yuhe Lin, Yang Weng, Yan Wu, Lufeng Zheng, Donghan Zheng, Qi Xi, Jingying Zhao   +7 more
wiley   +1 more source

Triglyceride Utilization by Human HeLa and Conjunctiva Cells in Tissue Culture

, 1959
Robert P. Geyer, JOYCE M. NEIMARK
openalex   +1 more source

Single‐Cell Dissection of the Biological Function and Molecular Features Underlying the Micropeptide LSMEM1 in Kidney

Advanced Science, EarlyView.
LSMEM1, an evolutionarily conserved micropeptide with extreme hydrophobicity (aliphatic index═113) and dynamic amphiphilicity (GRAVY═0.017), features a strong α‐helical transmembrane anchor (residues 64‐86). Single‐cell analysis reveals its critical role in renal lipid homeostasis.
Peimin Liu, Hong Zhang, Shanzhi Yang, Jiaoqing Li, Danfeng Wu, Haosen Xu, Huan Jiang, Yi Jing, Guoxiang Jin, Ruobing Liu, Ning Fan, Xiaoyan Bai   +11 more
wiley   +1 more source

ROUTE OF ABSORPTION OF FREE FATTY ACIDS AND TRIGLYCERIDES FROM THE INTESTINE

, 1951
Raymond Reiser, Melvin J. Bryson
openalex   +1 more source

Protein Spatial Structure Meets Artificial Intelligence: Revolutionizing Drug Synergy–Antagonism in Precision Medicine

Advanced Science, EarlyView.
This review comprehensively examines the applications of protein three‐dimensional structures and artificial intelligence in investigating drug synergistic and antagonistic effects. The research findings provide compelling evidence for the precision treatment of cancer and metabolic diseases, thereby promoting the development of personalized medicine ...
Anqi Lin, Chang Che, Aimin Jiang, Chang Qi, Antonino Glaviano, Zhijie Zhao, Zhirou Zhang, Zaoqu Liu, Ziyao Zhou, Quan Cheng, Shuofeng Yuan, Peng Luo   +11 more
wiley   +1 more source

Targeting Seipin to Alleviate Hepatic Steatosis in Zebrafish (Danio Rerio)

Advanced Science, EarlyView.
Seipin plays a crucial role in lipid metabolism. Seipin overexpression ameliorates high‐fat‐diet‐induced hepatic steatosis and enhances growth in zebrafish. Mechanistically, Seipin interacts with Plin2 to promote Plin2 degradation and enhances phosphatidylcholine synthesis via Seipin/CCTα/CHPT interactions.
Weijia Li, Yanan Shen, Zengqi Zhao, Baolin Li, Shunlang Wen, Rui Zhan, Qinghui Ai   +6 more
wiley   +1 more source