Results 11 to 20 of about 415 (104)

Allergic inflammation triggers dyslipidemia via IgG signalling [PDF]

Allergy, Volume 79, Issue 10, Page 2680-2699, October 2024.
Allergic inflammation induces a unique lipid signature in circulation that is characterized by triglyceride changes. Blood changes in triglyceride levels and composition during allergic inflammation are driven by IgG signalling. IgG‐mediated allergic inflammation regulates lipid metabolism, which may contribute to atherosclerosis and, ultimately, to ...
Nieves Fernández‐Gallego, Raquel Castillo‐González, Lucía Moreno‐Serna, Antonio J. García‐Cívico, Elisa Sánchez‐Martínez, Celia López‐Sanz, Ana Luiza Fontes, Lígia L. Pimentel, Ana Gradillas, David Obeso, René Neuhaus, Marta Ramírez‐Huesca, Ignacio Ruiz‐Fernández, Emilio Nuñez‐Borque, Yolanda R. Carrasco, Borja Ibáñez, Pilar Martín, Carlos Blanco, Coral Barbas, Domingo Barber, Luis M. Rodríguez‐Alcalá, Alma Villaseñor, Vanesa Esteban, Francisco Sánchez‐Madrid, Rodrigo Jiménez‐Saiz   +24 more
wiley   +8 more sources

Novel Relationship Between Plasmalogen Lipid Signatures and Carnosine in Humans

Molecular Nutrition &Food Research, Volume 65, Issue 20, October 2021., 2021
Carnosine has shown to improve glucose metabolism and cardiovascular risk. This study explores the relationship with the plasma lipidome by profiling >450 lipid species. Muscle carnosine and serum carnosinase‐1 activity (CN1) were negatively associated with 2‐h glucose and insulin sensitivity, respectively. This study identifies a strong association of
Jordi Mayneris‐Perxachs, Peter Meikle, Aya Mousa, Negar Naderpoor, José Manuel Fernández‐Real, Barbora de Courten   +5 more
wiley   +2 more sources

Serum Lipidome Signatures of Dogs with Different Endocrinopathies Associated with Hyperlipidemia [PDF]

, 2022
Hyperlipidemia (hypertriglyceridemia, hypercholesterolemia) is a common finding in human and veterinary patients with endocrinopathies (e.g., hypothyroidism and hypercortisolism (Cushing’s syndrome; CS)).
Baumgartner, Franziska, Boretti, Felicitas S, Burla, Bo, Selva, Jeremy John, Sieber-Ruckstuhl, Nadja S, Tham, Wai Kin, Wenk, Markus R   +6 more
core   +1 more source

Low triglyceride levels are associated with increased risk of immune-related adverse events in patients receiving immune checkpoint inhibitors. [PDF]

Oncoimmunology
Immune checkpoint inhibitors (ICI) have revolutionized cancer therapy by enhancing anti-tumor immune responses, yet their use can lead to immune-related adverse events (irAE), including neurological complications.
Möhn N, Narten E, Duzzi L, Thomas J, Grote-Levi L, Beutel G, Fröhlich T, Bollmann BA, Wirth T, von Wasielewski I, Gutzmer R, Heidel F, Pessler F, Zobl W, Schuchardt S, Ivanyi P, Nay S, Skripuletz T.   +17 more
europepmc   +3 more sources

Energy Metabolism, Metabolite, and Inflammatory Profiles in Human Ex Vivo Adipose Tissue Are Influenced by Obesity Status, Metabolic Dysfunction, and Treatment Regimes in Patients with Oesophageal Adenocarcinoma [PDF]

, 2023
Oesophageal adenocarcinoma (OAC) is a poor prognosis cancer with limited response rates to current treatment modalities and has a strong link to obesity.
Bhardwaj, Anshul, Butler, Christine, Donlon, Noel E., Donohoe, Claire L., Durand, Michael, Heeran, Aisling B., Lambe, Gerard, Mylod, Eimear, O\u27Connell, Fiona, Ramjit, Sinead, Ravi, Narayanasamy, Sheahan, Kevin P., Tansey, Paul, Welartne, Ivan, Yin, Xiaofei   +14 more
core   +2 more sources

Comparison and identification of serum metabolomic profiles in Stage B and Stage C ejection fraction preserved heart failure. [PDF]

Front Cardiovasc Med
BackgroundDisturbed metabolism correlates with the progression of heart failure with preserved ejection fraction (HFpEF). However, the discrepancy in metabolism between asymptomatic (Stage B) and symptomatic (Stage C) HFpEF patients remains unclear. This
Zou S, Zhang LW, Wang T, Wan YH, Chai K, Wang SM, Meng C, Cai JP, Wang H, Yang JF.   +9 more
europepmc   +3 more sources

Elevated lipid class concentrations in females with anorexia nervosa before and after intensive weight restoration treatment—A lipidomics study

International Journal of Eating Disorders, Volume 56, Issue 12, Page 2260-2272, December 2023., 2023
Abstract Objective To study the plasma lipidome of patients with anorexia nervosa (AN) before and after weight restoration treatment and report associations with AN subtypes and oral contraceptive pill (OCP) usage. Methods Quantitative shotgun lipidomics analysis was used to study plasma lipids of 50 female patients with AN before and after weight ...
Alia Arif Hussain, Mesut Bilgin, Jessica Carlsson, Mads Møller Foged, Erik Lykke Mortensen, Cynthia M. Bulik, René Klinkby Støving, Jan Magnus Sjögren   +7 more
wiley   +1 more source

Discovery of lipid profiles in plasma‐derived extracellular vesicles as biomarkers for breast cancer diagnosis

Cancer Science, Volume 114, Issue 10, Page 4020-4031, October 2023., 2023
This study investigated the use of lipid profiles in plasma‐derived extracellular vesicles as non‐invasive biomarkers for diagnosing, staging, and subtyping breast cancer. Lipid profiling effectively discriminated breast cancer progression and subtypes, suggesting its potential as a promising approach to breast cancer management.
Lin Liu, Masahiro Kawashima, Masahiro Sugimoto, Kazuhiro Sonomura, Fengling Pu, Wei Li, Masashi Takeda, Takayuki Goto, Kosuke Kawaguchi, Taka‐Aki Sato, Masakazu Toi   +10 more
wiley   +1 more source

Allergic inflammation triggers dyslipidemia via IgG signalling [PDF]

, 2023
Allergic diseases begin early in life and are often chronic, thus creating an inflammatory environment that may lead to metabolic disorders, although the underlying mechanisms remain incompletely understood.
Barbas, Coral, Barber, Domingo, Blanco, Carlos, Carrasco, Yolanda R., Castillo-González, Raquel, Esteban, Vanesa, Fernández-Gallego, Nieves, Fontes, Ana Luiza, García-Cívico, Antonio J., Gradillas, Ana, Ibáñez, Borja, Jiménez-Saiz, Rodrigo, López-Sanz, Celia, Martín, Pilar, Moreno-Serna, Lucía, Nuñez-Borque, Emilio, Obeso, David, Pimentel, Lígia L., Ramírez-Huesca, Marta, Rodríguez-Alcalá, Luis M., Ruiz-Fernández, Ignacio, Sánchez-Madrid, Francisco, Sánchez-Martínez, Elisa, Villaseñor, Alma   +23 more
core   +1 more source

Glycosphingolipids in human parasites

FEBS Open Bio, Volume 13, Issue 9, Page 1625-1635, September 2023., 2023
The parasites that infect humans and animals include protozoans and helminths (worms). Their secretions and cellular membranes contain complex glycomolecules including glycoproteins and glycolipids. A class of glycolipids shared between humans and parasites are the glycosphingolipids (GSLs) containing a lipid (ceramide) linked to a glycan ...
Richard D. Cummings
wiley   +1 more source