Results 31 to 40 of about 415 (104)

Interlaboratory comparison of standardised metabolomics and lipidomics analyses in human and rodent blood using the MxP® Quant 500 kit [PDF]

Metabolomics and lipidomics are pivotal in understanding phenotypic variations beyond genomics. However, quantification and comparability of mass spectrometry (MS)-derived data are challenging. Standardised assays can enhance data comparability, enabling
Adams, K., Adamski, J., Akyol, S., Ashrafi, N., Bottiglieri, T., Cecil, A., Chen, S., Contrepois, K., Gegner, H.M., Graham, S.F., Guan, X.L., Kalecký, K., Kastenmüller, G., Kirwan, J., Koal, T., Limonciel, A., Lintelmann, J., Mandal, R., O'Connell, T.M., Pham, H.T., Poschet, G., Saigusa, D., Schuchardt, S., Snyder, M.P., Thompson, J.W., Wishart, D., Yilmaz, A., Zararsiz, G.E., Zheng, J.   +28 more
core   +1 more source

Human genetic defects of sphingolipid synthesis

Journal of Inherited Metabolic Disease, Volume 48, Issue 1, January 2025.
Abstract Sphingolipids are ubiquitous lipids, present in the membranes of all cell types, the stratum corneum and the circulating lipoproteins. Autosomal recessive as well as dominant diseases due to disturbed sphingolipid biosynthesis have been identified, including defects in the synthesis of ceramides, sphingomyelins and glycosphingolipids.
Patricia Dubot, Frédérique Sabourdy, Thierry Levade   +2 more
wiley   +1 more source

Serum Lipidome and Metabolome Alterations in Obese Patients Undergoing Targeted Diet and Exercise Interventions: A Marker of Thyroid Function Recovery?

International Journal of Endocrinology, Volume 2025, Issue 1, 2025.
Purpose: Dietary and exercise interventions have the potential to modify thyroid hormone levels in individuals with obesity. This study investigates the specific mechanisms through which these interventions influence thyroid function, employing a multiomics approach.
Changxu Zhou, Heng Wang, Qingtao Yu, Jingxin Xin, Huiqi Chen, Ran Zhang, Qingbo Guan, Shanshan Shao, Liaqat Hussain   +8 more
wiley   +1 more source

Biochemistry and metabolism of mammalian blood glycosphingolipids [PDF]

, 1973
Thesis (Ph. D.)--Michigan State University.
Tao, Robert Vi-Pui, 1939-
core   +2 more sources

Studium etiopatogeneze mitochondriálních onemocnění [PDF]

, 2023
Mitochondrial disorders are a clinically, biochemically and genetically heterogeneous group of inherited disorders with a prevalence of about 1:5 000 live births. A common sign of those disorders is disruption of mitochondrial energetic metabolism.
Rákosníková, Tereza
core  

Correlations between the dipole potential, ErbB receptors and lipid rafts [PDF]

, 2018
A membránpotenciál legkevésbé ismert komponense, a dipólpotenciál a membránt alkotó lipidek karbonil csoportjainak és a membránhoz asszociálódó vízmolekulák dipólmomentumainak rendezett orientációja révén alakul ki.
Kovács, Tamás
core  

Identification of factors associated with non-responders to total joint replacement and sustained knee pain in primary osteoarthritis patients by epidemiological and multi-omic studies [PDF]

, 2023
Osteoarthritis (OA) is among the most common rheumatic diseases, affecting 30% of the world’s population over 60 years. Currently, total joint replacement (TJR) is considered the most effective treatment for end-stage OA.
Costello, Christie Alyssa
core  

Change of isoforms' spectra of α-l-fucosidase from human skin fibroblasts in intracellular storage of nonhydrolyzable substances [PDF]

, 1995
The effect of exogenous and endogenous products storage in lysosomes on the activity and multiple forms of α-l-fucosidase from human skin fibroblasts was investigated.
Artykova, Gulbahar, Beyer, Elena, Ivleva, Tatiana, Wiederschain, German   +3 more
core   +1 more source

Early life infection and proinflammatory, atherogenic metabolomic and lipidomic profiles at 12 months of age: a population-based cohort study

, 2021
BackgroundThe risk of adult onset cardiovascular and metabolic (cardiometabolic) disease accrues from early life. Infection is ubiquitous in infancy and induces inflammation, a key cardiometabolic risk factor, but the relationship between infection ...
Adam AT Smith, Anne-Louise Ponsonby, David P Burgner, Fiona Collier, Martin O’Hely, Mimi LK Tang, Peter D Sly, Peter J Meikle, Peter Vuillermin, Rebecca Rowland, Richard Saffery, Sarath Ranganathan, Satvika Burugupalli, Siroon Bekkering, Toby Mansell   +14 more
core   +1 more source

The diverse roles of the \textit{Pseudomonas aeruginosa} phospholipase PlcH and the \textit{Toxoplasma gondii} serine palmitoyltransferase in sphingolipid biochemistry. [PDF]

, 2014
Sphingolipids are essential for cell survival for almost all eukaryotic cells. Due to the large variety in sphingolipid structure, they possess a wide range of functions from acting as structural components of membranes to participating in cell ...
THYE, JULIE,KRISTINE
core