Results 101 to 110 of about 67,879 (252)

An interpretable machine learning model for predicting metabolic dysfunction‐associated steatotic liver disease in patients with type 2 diabetes

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aim Patients with type 2 diabetes mellitus (T2DM) exhibit an elevated prevalence of metabolic dysfunction‐associated steatotic liver disease (MASLD) and are at greater risk of liver‐related adverse events. Existing non‐invasive tools show limited diagnostic performance in this population.
Zhuolin Zhou   +5 more
wiley   +1 more source

Safety and efficacy of the therapy with CD4 + CD25highCD127‐T regulatory cells: When paediatric patient becomes adult

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aim CD4 + CD25highCD127‐T regulatory cells (Tregs) remain a drug candidate for immunotherapy of type 1 diabetes. We completed three trials testing Tregs in recently diagnosed type 1 diabetes children. Here, we looked for long‐term safety and efficacy aspects important in the authorisation of this therapy.
Marta Bandura   +18 more
wiley   +1 more source

Pituitary hyperplasia mimicking macroadenoma associated with primary hypothyroidism in a patient with selective L-thyroxine malabsorption [PDF]

open access: yes, 2017
We present the case of a 29-year-old woman who developed a severe hypothyroidism induced by a thyroxine malabsorption and a secondary pituitary hyperplasia.
Romanelli, Francesco   +4 more
core   +1 more source

Aetiological relevance of haematological, biochemical and endocrine parameters on equine odontoclastic tooth resorption and hypercementosis (EOTRH)

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background The dental syndrome EOTRH is a painful, progressive dental disease with an unknown aetiology. The often painful nature of EOTRH emphasises the need for a better knowledge of the underlying pathogenic mechanism and risk factors. A comparative analysis of haematological, biochemical and endocrine values in EOTRH‐affected and non ...
Melusine Tretow   +2 more
wiley   +1 more source

Treatment of hypothyroidism with levothyroxine plus liothyronine: a randomized, double-blind, crossover study

open access: yesArchives of Endocrinology and Metabolism, 2016
Objective To compare the effects of a unique fixed combination levothyroxine/liothyronine (LT4/LT3) therapy in patients with primary hypothyroidism. Subjects and methods This is a randomized, double-blind, crossover study.
Juliana Kaminski   +4 more
doaj   +1 more source

Genetic Parameter Estimation for Plasma Biomarkers Associated With Energy Reserves During Critical Physiological Stages in Sheep

open access: yesJournal of Animal Breeding and Genetics, EarlyView.
ABSTRACT The ability of ruminants to mobilise and restore body reserves (BR) over time, referred to as BR dynamics, is currently considered an interesting biological component to be included in breeding programs targeting enhanced BR resilience. However, genetic studies of proxies for BR levels and BRD remain scarce, particularly in small ruminants ...
Agnes Nyamiel   +8 more
wiley   +1 more source

Association between thyroid function and acute mountain sickness upon rapid ascent to 3650 m in euthyroid lowlanders in China

open access: yesExperimental Physiology, EarlyView.
This study evaluated the association between baseline thyroid hormones levels, sensitivity index and the incidence of AMS in 70 healthy individuals traveling from Beijing (44 m above sea level) to Lhasa (3650 m above sea level). The dataset was divided into a training set (n = 56) and a validation set (n = 14) at an ratio of 8:2.
Cencen Wu   +13 more
wiley   +1 more source

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