Results 61 to 70 of about 95,645 (304)

Connexin 26 Functions as a Direct Transcriptional Regulator During the Cochlea Development

Advanced Science, EarlyView.
Connexin26 can not only form intercellular channels that mediate rapid communication on the cell membrane, but also enter the nucleus as a transcription factor to directly regulate the transcription of nuclear genes. In the developing cochlea, Cx26 can control the maturation of the molecular scissor ADAM10 by regulating the transcription of TspanC8 ...
Xiaozhou Liu, Le Xie, Yuan Jin, Sen Chen, Xinyu Shi, Yanjun Zong, Zhengdong Zhao, Wei‐Jia Kong, Yu Sun   +8 more
wiley   +1 more source

Effect Of Organic Selenium And Iodine Supplementation On Selenium And Thyroid Hormones Status Of Lactating Ewes And Lambs

Acta Veterinaria, 2015
The aim of this research was to determine the influence of 56-days (from day 4 to day 60 post partum) of simultaneous supplementation of selenium (Se) and iodine (I) enriched Chlorella algae on blood and urine Se concentrations and thyroid hormone levels
Konečný Roman, Hasoňová Lucie, Trávníček Jan, Samková Eva, Hladký Jan, Křížová Zuzana   +5 more
doaj   +1 more source

Evaluation of thyroid profi le for renal dysfunction in dairy cows [PDF]

Науковий вісник ветеринарної медицини, 2020
Chronic pathological process in kidney saff ect the hypothalamic-pituitary-thyroid system and peripheral metabolism of thyroid hormones. Pathological blood components, which accumulate due to intoxication of metabolic products, the uremic toxins, can aff
Vovkotrub N., Melnyk A., Bezukh V., Tyshkivskii M.   +3 more
doaj   +1 more source

Thyroid hormones correlate with field metabolic rate in ponies, Equus ferus caballus [PDF]

, 2016
Acknowledgments The authors thank Jürgen Dörl for technical help and for taking care of the animals and Peter Thompson for technical assistance with the doubly labelled water analysis.
Brinkmann, Lea, Gerken, Martina, Hambly, Catherine, Riek, Alexander, Speakman, John R   +4 more
core   +1 more source

Fe‐S Protein FDX1 Triggers Tumor‐Intrinsic Innate Immunity via Mitochondrial Nucleic Acids Release to Orchestrate Ferroptosis in CCRCC

Advanced Science, EarlyView.
Restoration of the mitochondrial Fe–S protein FDX1 suppresses clear cell renal cell carcinoma by coupling ferroptosis with tumor‐intrinsic innate immune activation. FDX1 induces mitochondrial dysfunction and mtDNA/mt‐dsRNA release, activating cGAS–STING and RIG‐I/MDA5–MAVS signaling to elicit type I interferon responses, thereby promoting antigen ...
Xing Huang, Shaoqing Yu, Wenjie Wei, Wen Tao, Tianwei Cai, Lequan Wen, Jiali Ye, Chi Zhang, Huayi Feng, Senming Cao, Baojun Wang, Xin Ma, Yan Huang, Xu Zhang   +13 more
wiley   +1 more source

Thyroid Hormone Levels in Patients with Head and Neck Cancer Undergoing Radiochemotherapy: A Retrospective Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Head and Neck Cancers (HNCs) are a common type of cancer, affecting approximately 6% of the global cancer burden. The treatment of HNC often involves Radiochemotherapy (RCT), which can have adverse effects on the thyroid gland.
Nidhi Rohan Purandare, Meenakshi, Shilpa Jain, Neeti Patel, Sarita A Shinde   +4 more
doaj   +1 more source

Biomarkers of selenium status in dogs [PDF]

, 2016
Background: Inadequate dietary selenium (Se) intake in humans and animals can lead to long term health problems, such as cancer. In view of the owner's desire for healthy longevity of companion animals, the impact of dietary Se provision on long term ...
Du Laing, Gijs, Gray, Kerry, Hesta, Myriam, Janssens, Geert, Staunton, Ruth, Van Zelst, Marielle   +5 more
core   +2 more sources

Serum triiodothyronine levels and inflammatory cytokine production capacity

AGE, 2011
Increasing evidence suggests that pro-inflammatory cytokines are at play in lowering peripheral thyroid hormone levels during critical illness. Conversely, thyroid hormones have been suggested to enhance production of inflammatory cytokines.
M. Rozing, R. Westendorp, A. Maier, C. Wijsman, M. Frölich, A. D. de Craen, D. van Heemst   +6 more
semanticscholar   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Risk of cardiac, neuropsychiatric and musculoskeletal adverse events with levothyroxine: Systematic review

British Journal of Clinical Pharmacology, EarlyView.
Abstract Levothyroxine (LT4) is the standard treatment for hypothyroidism and the most widely prescribed medication worldwide. Although generally safe, regulatory reports list potential cardiac, neuropsychiatric and musculoskeletal adverse events (AEs). Clarifying their clinical relevance is essential.
Bala Swetha Baskaran, Mohammad Ali Omrani, Flory T. Muanda   +2 more
wiley   +1 more source