Results 51 to 60 of about 209,912 (265)
Quantized Response and Topology of Insulators with Inversion Symmetry [PDF]
, 2010 We study three dimensional insulators with inversion symmetry, in which other point group symmetries, such as time reversal, are generically absent.
A. A. Abrikosov +10 more
core +3 more sources
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
TRIM29 in Cutaneous Squamous Cell Carcinoma
Frontiers in Medicine, 2021 Tripartite motif (TRIM) proteins play important roles in a wide range of cell physiological processes, such as signal transduction, transcriptional regulation, innate immunity, and programmed cell death.
Che-Yuan Hsu +2 more
doaj +1 more source
Precision autophagy directed by receptor regulators - emerging examples within the TRIM family. [PDF]
J Cell Sci, 2016 ABSTRACT Selective autophagy entails cooperation between target recognition and assembly of the autophagic apparatus. Target recognition is conducted by receptors that often recognize tags, such as ubiquitin and galectins, although examples of selective autophagy independent of these tags are emerging.
Kimura T, Mandell M, Deretic V.
europepmc +3 more sources
, 2013 We present a microscopic approach in the framework of Sklyanin's quantum separation of variables (SOV) for the exact solution of 1+1-dimensional quantum field theories by integrable lattice regularizations.
Niccoli, G.
core +1 more source
Evolution of a TRIM5-CypA Splice Isoform in Old World Monkeys [PDF]
, 2011 The TRIM family proteins share a conserved arrangement of three adjacent domains, an N-terminal RING domain, followed by one or two B-boxes and a coiled-coil, which constitutes the tripartite-motif for which the family is named. However, the C-termini of
Farzan, Michael Reynolds +7 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
TRIM E3 ligases interfere with early and late stages of the retroviral life cycle.
PLoS Pathogens, 2008 Members of the TRIpartite interaction Motif (TRIM) family of E3 ligases have been shown to exhibit antiviral activities. Here we report a near comprehensive screen for antiretroviral activities of 55 TRIM proteins (36 human, 19 mouse).
Pradeep D Uchil +4 more
doaj +1 more source
Investigating genetic drivers of dermatomyositis pathogenesis using meta-analysis
Heliyon, 2020 Aims: Dermatomyositis (DM) is a progressive, idiopathic inflammatory myopathy with poorly understood pathogenesis. A hallmark of DM is an increased risk for developing breast, ovarian, and lung cancer.
Jihad Aljabban +17 more
doaj +1 more source