Results 181 to 190 of about 5,785,343 (209)

Trim Proteins as Ring Finger E3 Ubiquitin Ligases

2012
The tripartite motif(TRIM) proteins harboring the RING finger, B-box and coiled-coil (RBCC) domain motifs form a large protein family. The members of this family are involved in various biological processes, including growth, differentiation, apoptosis and transcription and also in diseases and oncogenesis.
Kazuhiro, Ikeda, Satoshi, Inoue
openaire   +2 more sources

Therapeutic, diagnostic and prognostic values of TRIM proteins in prostate cancer

Pharmacological Reports, 2023
Xiaojiang Li, Yuzhuo Bai, Ke Feng, Zhendong Chu, Haijun Li, Zhicheng Lin, Lin Tian   +6 more
semanticscholar   +1 more source

TRIM Proteins in Inflammation: from Expression to Emerging Regulatory Mechanisms

Inflammation, 2021
Luting Yang, Haibin Xia
semanticscholar   +1 more source

The TRIM proteins in cancer: from expression to emerging regulatory mechanisms

Clinical and Translational Oncology, 2021
A. Mohammadi, M. S. Pour Abbasi, S. Khorrami, S. Khodamoradi, Z. Mohammadi Goldar, F. Ebrahimzadeh   +5 more
semanticscholar   +1 more source

The role of TRIM proteins in PRR signaling pathways and immune-related diseases.

International Immunopharmacology, 2021
Zheng Jin, Zhenhua Zhu
semanticscholar   +1 more source

TRIM proteins in lung cancer: Mechanisms, biomarkers and therapeutic targets.

Life Science, 2021
Weihua Zhan, Song-zhao Zhang
semanticscholar   +1 more source

Structural characterization of TRIM family proteins

2018
TRIM proteins are E3 ubiquitin ligases that participate in many cellular processes and signaling pathways, such as immune system response. Several TRIM proteins were shown to form antiparallel coiled-coil dimers which position catalytic RING domains on the opposite sides of an elongated rod. As RING dimerization is necessary for its enzymatic activity,
openaire   +1 more source

Tumor suppressor p53 and TRIM family proteins

Cancer Cell & Microenvironment, 2015
Tumor suppressor p53 plays a key role in maintaining genomic stability and tumor suppression. As a transcription factor, p53 mainly exerts its function in tumor suppression through transcriptional regulation of its target genes to regulate a wide variety of cellular responses. To maintain its proper function, p53 protein levels and activity are tightly
openaire   +1 more source

TRIM28 promotes the escape of gastric cancer cells from immune surveillance by increasing PD-L1 abundance

Signal Transduction and Targeted Therapy, 2023
Wenyi Wei
exaly  

TRIM5α restricts poxviruses and is antagonized by CypA and the viral protein C6

Nature, 2023
Jonas Dutra Albarnaz, Geoffrey Lilley Smith   +1 more
exaly