Results 71 to 80 of about 12,013 (243)
Hepatic Ischemia and Reperfusion Injury and Trauma: Current Concepts [PDF]
, 2013 Context: Ischemia-reperfusion injury is a fascinating topic which has drawn a lot of interest in the last several years. Hepatic ischemia reperfusion injury may occur in a variety of clinical situations.
Papadopoulos, D. +3 more
core +2 more sources
The emerging role of Nrf2 in heart failure: From cardioprotection to therapeutic approaches
ESC Heart Failure, EarlyView.Nrf2 signalling is impaired in heart failure, contributing to oxidative stress, mitochondrial dysfunction, and ferroptosis, which drive neurohormonal activation, inflammation, and ischaemia‐reperfusion injury. This loss of Nrf2 activity exacerbates hypertension, diabetic cardiomyopathy, and cardiotoxicity, accelerating progression to overt heart ...
Emiliano Fiori +9 more
wiley +1 more source
Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors
British Journal of Pharmacology, EarlyView.Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen +3 more
wiley +1 more source
Кардиоваскулярная терапия и профилактика, 2013 Aim. To assess the effects of the four-month trimetazidine MR therapy on the parameters of 24-hour electrocardiogram (ECG) monitoring and heart rate variability (HRV) in patients with stable coronary heart disease (CHD).Material and methods.
M. V. Novikova, M. G. Glezer
doaj +1 more source
Сибирский научный медицинский журнал, 2022 Aim of the study was to assess the degree of myocardial ischemia in rats on chronic in vivo model, with a simultaneous assessment of justification for the use of trimetazidine. Material and methods. The object of the study was 120 male inbred Wistar rats,
A. Avagimyan
semanticscholar +1 more source
Selection of medication in hospitalised elderly patients with Angina Pectoris [PDF]
, 2004 Objective: To evaluate medication changes in hospitalised elderly patients diagnosed with angina pectoris and to compare the selection of medication with evidence-based treatment guidelines. Design: Review of medical notes and patient interview. Setting:
Cacciottolo, Joseph M. +2 more
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European Journal of Heart Failure, Volume 27, Issue 9, Page 1720-1736, September 2025.Improving clinical translation of mitoprotective therapies. 31P MRI, phosphorus‐31 magnetic resonance imaging; hiPSC‐CM, human‐induced pluripotent stem cell‐derived cardiomyocyte; IHD, ischaemic heart disease. Abstract Acute myocardial infarction (MI) remains a major cause of death and disability worldwide.
Melanie Paillard +29 more
wiley +1 more source
Cardioprotective Effect of Trimetazidine in Cardiac Contusion: Experimental Study
Общая реаниматология, 2008 Objective: to study the efficiency of pre-administration of trimetazidine in experimental cardiac contusion in order to lower the degree of posttraumatic myocardial dysfunction.
O. V. Korpacheva, V. T. Dolgikh
doaj +1 more source
PLoS ONE, 2022 Objective To explore the effect of adding trimetazidine to other anti-anginal drugs on the functional capacity of ischemic heart disease (IHD) patients not suitable for revascularization when compared to first-line antianginal drugs alone.
Alyaa M Ajabnoor, Amna H. Mukhtar
semanticscholar +1 more source
Особенности кардиопротекторного эффекта триметазидина при экспериментальном кардиосклерозе у крыс с различной степенью чувствительности к гипоксии [PDF]
, 2015 ГИПОКСИЯАНОКСИЯЛИПИДОВ ПЕРЕКИСНОЕ ОКИСЛЕНИЕПЕРЕКИСНОЕ ОКИСЛЕНИЕ ЛИПИДОВСКЛЕРОЗкардиосклероз ...
Сатурская, А. С.
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