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Dual valve Achromobacter endocarditis in a long-term acute care unit: a case report and review of the literature. [PDF]

J Med Case Rep
Abdelgalil M.
europepmc   +1 more source

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Mechanisms of Resistance to Trimethoprim, the Sulfonamides, and Trimethoprim-Sulfamethoxazole

Clinical Infectious Diseases, 1982
A variety of different mechanisms are known to be responsible for either natural or acquired resistance to trimethoprim, the sulfonamides, or trimethoprim-sulfonamide combinations. Some mechanisms of obvious clinical importance have been studied intensively. Among these are unique bypass mechanisms such as the synthesis of drug-resistant, plasmid-coded
R L Then
exaly   +3 more sources

Trimethoprim-Sulfamethoxazole

Mayo Clinic Proceedings, 1983
The antimicrobial combination of trimethoprim and sulfamethoxazole is active in vitro against a variety of gram-positive and gram-negative bacteria. Clinically, it is useful for treatment and prophylaxis of various infections of the genitourinary tract and certain infections of the respiratory and gastrointestinal tracts.
F R, Cockerill, R S, Edson
openaire   +6 more sources

Degradation of Trimethoprim

Journal of Pharmaceutical Sciences, 1989
Trimethoprim undergoes thermally and photochemically catalyzed hydrolysis or oxidation to give rise to at least five products. The structures of these compounds were determined by physical methods and it was found that the resonance of C-5 in the 13C NMR spectrum is indicative of the substitution pattern of the resultant amino hydroxy pyrimidines.
J J, Bergh, J C, Breytenbach, P L, Wessels   +2 more
openaire   +2 more sources

Hypersensitivity to trimethoprim

Allergy, 1992
We present two patients who experienced life‐threatening immediate reactions and one patient who developed generalized urticaria following oral administration of trimethoprim (TMP) and sulfamethoxazole (SMX) combination. Skin prick tests with TMP were positive in the three patients. No patients reacted to skin prick tests with SMX.
M D, Alonso, C, Marcos, I, Davila, B, de la Hoz, J A, Martin, F, Parra, M L, Diez   +6 more
openaire   +2 more sources

Molecular Characterisation of Trimethoprim Resistance in Escherichia coli and Klebsiella pneumoniae during a Two Year Intervention on Trimethoprim Use

PLoS ONE, 2010
BACKGROUND: Trimethoprim resistance is increasing in Enterobacteriaceae. In 2004-2006 an intervention on trimethoprim use was conducted in Kronoberg County, Sweden, resulting in 85% reduction in trimethoprim prescriptions.
Martin Sundqvist, G Kahlmeter
exaly   +2 more sources

Trimethoprim-Sulfamethoxazole

Mayo Clinic Proceedings, 1999
After 25 years of use in the United States, trimethoprim-sulfamethoxazole (TMP-SMX) is widely prescribed for various indications. By virtue of sequential blockade of microbial folic acid synthesis, the antimicrobial combination has excellent in vitro inhibitory activity against many common respiratory and urinary tract pathogens, as well as many ...
openaire   +2 more sources

The Antimetabolites: The Sulfonamides and Trimethoprim (Trimethoprim-Sulfamethoxazole)

2000
Abstract The sufonamides were the first effective chemotherapeutic agents to be used systematically for the treatment of bacterial infections. Sulfonamide-containing compounds were synthesized early in this century by German chemists for use as dyes.
Eric M Scholar, William B Pratt
openaire   +1 more source

Trimethoprim*

Medical Journal of Australia, 1985
G, Rich, B, Mee
openaire   +3 more sources

TRIMETHOPRIM ALONE

The Lancet, 1980
Rosalind Maskell, Linda Pead, David Greenwood   +2 more
openaire   +4 more sources