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Hypersensitivity to trimethoprim
Allergy, 1992We present two patients who experienced life‐threatening immediate reactions and one patient who developed generalized urticaria following oral administration of trimethoprim (TMP) and sulfamethoxazole (SMX) combination. Skin prick tests with TMP were positive in the three patients. No patients reacted to skin prick tests with SMX.
M D, Alonso +6 more
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Mayo Clinic Proceedings, 1999
After 25 years of use in the United States, trimethoprim-sulfamethoxazole (TMP-SMX) is widely prescribed for various indications. By virtue of sequential blockade of microbial folic acid synthesis, the antimicrobial combination has excellent in vitro inhibitory activity against many common respiratory and urinary tract pathogens, as well as many ...
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After 25 years of use in the United States, trimethoprim-sulfamethoxazole (TMP-SMX) is widely prescribed for various indications. By virtue of sequential blockade of microbial folic acid synthesis, the antimicrobial combination has excellent in vitro inhibitory activity against many common respiratory and urinary tract pathogens, as well as many ...
openaire +2 more sources
The Antimetabolites: The Sulfonamides and Trimethoprim (Trimethoprim-Sulfamethoxazole)
2000Abstract The sufonamides were the first effective chemotherapeutic agents to be used systematically for the treatment of bacterial infections. Sulfonamide-containing compounds were synthesized early in this century by German chemists for use as dyes.
Eric M Scholar, William B Pratt
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Trimethoprim and the sulphonamides
Veterinary Record, 1970M, Barnett, S R, Bushby
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