Results 81 to 90 of about 51,636 (262)

Rescue of morphological defects in Streptomyces venezuelae by the alkaline volatile compound trimethylamine

Microbiology Spectrum
Microorganisms can produce a vast diversity of volatile organic compounds of different chemical classes that are capable of mediating intra- and inter-kingdom interactions. In this study, we showed that the soil-dwelling bacterium Streptomyces venezuelae
Yanping Zhu, Yanhong Zeng, Meng Liu, Ting Lu, Xiuhua Pang   +4 more
doaj   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source

Novel treatment strategies for chronic kidney disease: insights from the animal kingdom [PDF]

, 2018
Many of the >2 million animal species that inhabit Earth have developed survival mechanisms that aid in the prevention of obesity, kidney disease, starvation, dehydration and vascular ageing; however, some animals remain susceptible to these ...
Arnold, Walter, Johnson, Richard J., Kuro-o, Makoto, Lanaspa, Miguel, Painer, Johanna, Ruf, Thomas, Shiels, Paul G., Stenvinkel, Peter   +7 more
core   +1 more source

Microcoulometric analysis of trimethylamine dehydrogenase [PDF]

Biochemical Journal, 1988
Trimethylamine dehydrogenase, which contains one covalently bound 6-S-cysteinyl-FMN and one Fe4S4 cluster per subunit of molecular mass 83,000 Da, was purified to homogeneity from the methylotrophic bacterium W3A1. Microcoulometry at pH 7 in 50 mM-Mops buffer containing 0.1 mM-EDTA and 0.1 M-KCl revealed that the native enzyme required the addition of ...
Barber, M J., Pollock, V., Spence, J. T.
openaire   +3 more sources

Expanded Scorpionate and Siderophore‐Inspired Ligands: From Foundational Designs to Modern Applications

European Journal of Inorganic Chemistry, EarlyView.
The concept of scorpionate ligands has evolved significantly since the introduction of tris(pyrazolyl)borate. By integrating a biological supramolecular ligand scaffold with the classic scorpionate architecture, researchers have made notable strides in mimicking the active sites of nitrogenase and advancing homogeneous catalysis.
Austin Winfield Medley, Trandon Allen Bender   +1 more
wiley   +1 more source

Understanding the mechanisms of efficacy of fecal microbiota transplant in treating recurrent Clostridioides difficile infection and beyond: the contribution of gut microbial-derived metabolites

Gut Microbes, 2020
Fecal microbiota transplant (FMT) is a highly-effective therapy for recurrent Clostridioides difficile infection (rCDI), and shows promise for certain non-CDI indications.
Laura Martinez-Gili, Julie a K McDonald, Zhigang Liu, Dina Kao, Jessica R Allegretti, Tanya M Monaghan, Grace F Barker, Jesús Miguéns Blanco, Horace R T Williams, Elaine Holmes, Mark R Thursz, Julian R Marchesi, Benjamin H Mullish   +12 more
doaj   +1 more source

Escherichia coli TatA and TatB Proteins Have N-out, C-in Topology in Intact Cells [PDF]

, 2012
The twin arginine protein transport (Tat) system translocates folded proteins across the cytoplasmic membrane of prokaryotes and the thylakoid membrane of chloroplasts.
Alami, Bartolomé, Bauer, Berks, Bernhardt, Berthelmann, Bogsch, Bolhuis, Bryson, Buchanan, Casadaban, Chan, Cline, Cline, Dabney-Smith, Dabney-Smith, de Leeuw, De Leeuw, Gohlke, Gouffi, Greene, Hashimoto-Gotoh, Heijne, Hu, Ize, Jack, Jack, Laemmli, Leake, Lee, Leive, Lu, Maegawa, Maldonado, Mori, Mori, Palmer, Palmer, Porcelli, Punginelli, Richter, Sambrook, Sargent, Sargent, Sargent, Sauvé, Silvestro, Simons, Stanley, Stevenson, Tarry, Tarry, Towbin, Walther, Wang, Weiner, Wessel, Wexler, Yen   +58 more
core   +3 more sources

From Phosphinimines to Four‐Membered SiCPN Cations: Insights Into N–Si Bonding and Ring Strain

European Journal of Inorganic Chemistry, EarlyView.
Sterically tuned N‐silyl phosphinimines enable four‐membered SiCPN cations. Hydride abstraction yields cyclic cations for Me and iPr substituents at silicon, while tBu gives a protonated intermediate. Multinuclear NMR spectroscopy, X‐ray crystallography, thermochemical density functional theory investigations, and natural bond orbital analyses reveal ...
Alexander Falk, Jonathan O. Bauer
wiley   +1 more source

Prebiotic, Probiotic, and Synbiotic Supplementation in Chronic Kidney Disease: A Systematic Review and Meta-analysis [PDF]

, 2019
Gut dysbiosis has been implicated in the pathogenesis of chronic kidney disease (CKD). Restoring gut microbiota with prebiotic, probiotic, and synbiotic supplementation has emerged as a potential therapeutic intervention but has not been systematically ...
Campbell, Katrina L., Johnson, David W., McFarlane, Catherine, Ramos, Christiane I.   +3 more
core   +1 more source

Emerging Trends in Organic Photoreactions Utilizing Disulfides

European Journal of Organic Chemistry, EarlyView.
Disulfides are versatile, nontoxic alternatives to metal photocatalysts. This review explores their role as photoactivated thiyl‐radical precursors and bifunctional catalysts (HAT/electron shuttling) in diverse transformations. Strategies for electronic tuning and development into recyclable heterogeneous materials are highlighted for sustainable ...
Sunil Kumar, Bolormaa Bayarkhuu, Hong Y. Cho, Jeehye Byun   +3 more
wiley   +1 more source