Results 61 to 70 of about 37,079 (207)

Trimethylamine and trimethylamine N-oxide, a flavin-containing monooxygenase 3 (FMO3)-mediated host-microbiome metabolic axis implicated in health and disease [PDF]

, 2016
Flavin-containing monooxygenase 3 (FMO3) is known primarily as an enzyme involved in the metabolism of therapeutic drugs. However, on a daily basis we are exposed to one of the most abundant substrates of the enzyme, trimethylamine, which is released ...
Phillips, IR, Shephard, EA, Fennema, D
core  

Molar Kerr constants and solute polarizability anisotropies of ammonia, trimethylamine, trimethylamine oxide and 1,4-Diazabicyclo[2,2,2]octane

, 1977
Electric dipole moments and molar Kerr constants are reported for ammonia, trimethylamine, trimethylamine oxide, 1,4- diazabicyclo[2,2,2]octane and its monohydrate in non-polar solvents.
RK Pierens, KE Calderbank, RS Armstrong, MJ Aroney   +3 more
core   +1 more source

Resistant Potato Starch Supplementation Increases the Serum Levels of Choline and Sphingomyelins Without Affecting Trimethylamine Oxide Levels

Metabolites
Background/Objectives: The prebiotic effect of resistant potato starch (RPS) has been demonstrated, but the role of this nutrient in choline metabolism and the production of microbially modified choline-derived toxins is unknown.
Jason R. Bush, Jun Han, David R. Goodlett   +2 more
doaj   +1 more source

From heart failure and kidney dysfunction to cardiorenal syndrome: TMAO may be a bridge

Frontiers in Pharmacology, 2023
The study of trimethylamine oxide (TMAO), a metabolite of gut microbiota, and heart failure and chronic kidney disease has made preliminary achievements and been summarized by many researchers, but its research in the field of cardiorenal syndrome is ...
Jialun Zhang, Peining Zhu, Siyu Li, Yufei Gao, Yue Xing   +4 more
doaj   +1 more source

Choline Metabolism to the Proatherogenic Metabolite Trimethylamine Occurs Primarily in the Distal Colon Microbiome In Vitro

Metabolites
Background/Objectives: Gut microbial metabolism of choline and related quaternary amines to trimethylamine (TMA) is the first step in the production of trimethylamine N-oxide (TMAO), a circulating metabolite that contributes to the development of ...
Anthony M. Buckley, Sarah Zaidan, Michael G. Sweet, Duncan J. Ewin, Juanita G. Ratliff, Aliyah Alkazemi, William Davis Birch, Ashley M. McAmis, Andrew P. Neilson   +8 more
doaj   +1 more source

Amines in Fish Muscle: II. Development of Trimethylamine and Other Amines

, 1945
Relatively large amounts of nonvolatile higher amines are formed during proteolysis of fish muscle by bacteria. This follows closely the formation of trimethylamine. Fresh fish contain 0.2 mg.
W. J. Dyer, Yvonne A. Mounsey
core   +1 more source

Advanced In Vitro Platforms for Experimental Liver Research: From Organoids and Liver‐on‐Chip to Omics and Artificial Intelligence

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Hepatocytes perform essential physiological functions in the human body. Gaining more profound insight into the liver structure, diseases, and physiology by using in vitro models can help to propose more relevant clinical applications. Conventional in vitro liver models, such as two‐dimensional (2D) cell cultures, fail to adequately replicate ...
Seyedeh Kiana Teymorian, Pedram Asadi Sarabi, Abbas Piryaei, Massoud Vosough   +3 more
wiley   +1 more source

Trimethylamine : MAK Value Documentation, 2018

, 2018
The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has evaluated a momentary value for trimethylamine [75‐50‐3].
Hartwig, Andrea, Deutsche Forschungsgemeinschaft. Ständige Senatskommission zur Prüfung Gesundheitsschädlicher Arbeitsstoffe, MAK Commission   +2 more
core   +1 more source

Molybdenum‐carbothioamide complexes as potential single‐source precursors for MoS2 thin film

Bulletin of the Korean Chemical Society, EarlyView.
Novel molybdenum complexes were synthesized to apply for deposition of Mo‐containing thin films. All complexes were characterized, and they are likely to be used as single‐source precursors for MoS2 thin films. Abstract Molybdenum disulfide (MoS2) thin films are widely used in batteries, transistors, supercapacitors, and 2D materials owing to their ...
Sung Kwang Lee, Dagyum Yoo, Tae Wook Kim, Taek‐Mo Chung   +3 more
wiley   +1 more source

The complex metabolism of trimethylamine in humans: Endogenous and exogenous sources

, 2016
Trimethylamine (TMA) is a tertiary amine with a characteristic fishy odour. It is synthesised from dietary constituents, including choline, L-carnitine, betaine and lecithin by the action of microbial enzymes during both healthy and diseased conditions ...
Chhibber-Goel, Jyoti, Parakh, Neeraj, Gaur, Anamika, Sharma, Amit, Singhal, Varsha, Bhargava, Balram   +5 more
core   +1 more source