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Trimethylamine N-oxide in cardiovascular disease: Pathophysiology and the potential role of statins.
Life ScienceCardiovascular diseases are one of the leading causes of mortality and morbidity worldwide, with the total number of cases increasing to 523 million in 2019.
Fakhar Latif +9 more
semanticscholar +1 more source
Trimethylamine N-Oxide and Risk of Cardiovascular Disease and Mortality
Current Nutrition Reports, 2018Trimethylamine N-oxide (TMAO) is a gut microbiota-dependent metabolite produced from choline and phosphatidylcholine. Trimethylamine N-oxide was found associated with enhanced atherosclerosis and thrombosis in vitro and in vivo. We summarized available clinical studies which investigated TMAO's role in predicting prognostic outcomes, including ...
Chanavuth, Kanitsoraphan +3 more
openaire +2 more sources
Trimethylamine-N-oxide and its biological variations in vegetarians
European Journal of Nutrition, 2016Restriction of animal foods and choline may affect plasma trimethylamine-N-oxide (TMAO). In vegetarians, we investigated the association between TMAO concentrations and the strictness of the diet or sex. We also studied the biological variations of TMAO in vegans.Concentrations of plasma TMAO and choline metabolites were measured in 38 vegans and 67 ...
Obeid, Rima +3 more
openaire +3 more sources
Cancer
Dietary intake influences gut microbiome composition, which in turn may be associated with colorectal cancer (CRC). Associations of the gut microbiome with colorectal carcinogenesis may be mediated through bacterially regulated, metabolically active ...
Doratha A. Byrd +9 more
semanticscholar +1 more source
Dietary intake influences gut microbiome composition, which in turn may be associated with colorectal cancer (CRC). Associations of the gut microbiome with colorectal carcinogenesis may be mediated through bacterially regulated, metabolically active ...
Doratha A. Byrd +9 more
semanticscholar +1 more source
The association between the gut microbiota metabolite trimethylamine N-oxide and heart failure
Frontiers in MicrobiologyThis systematic review explores the relationship between the gut microbiota metabolite trimethylamine N-oxide (TMAO) and heart failure (HF), given the significant impact of TMAO on cardiovascular health.
Zharkyn Jarmukhanov +6 more
semanticscholar +1 more source
Gut Microbial Metabolite Trimethylamine N -Oxide Aggravates Pulmonary Hypertension
American Journal of Respiratory Cell and Molecular Biology, 2022Kai Yang, Haiyang Tang, Jian Wang
exaly

