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Trimethylamine N-oxide in cardiovascular disease: Pathophysiology and the potential role of statins.

Life Science
Cardiovascular diseases are one of the leading causes of mortality and morbidity worldwide, with the total number of cases increasing to 523 million in 2019.
Fakhar Latif   +9 more
semanticscholar   +1 more source

Trimethylamine N-Oxide and Risk of Cardiovascular Disease and Mortality

Current Nutrition Reports, 2018
Trimethylamine N-oxide (TMAO) is a gut microbiota-dependent metabolite produced from choline and phosphatidylcholine. Trimethylamine N-oxide was found associated with enhanced atherosclerosis and thrombosis in vitro and in vivo. We summarized available clinical studies which investigated TMAO's role in predicting prognostic outcomes, including ...
Chanavuth, Kanitsoraphan   +3 more
openaire   +2 more sources

Trimethylamine-N-oxide and its biological variations in vegetarians

European Journal of Nutrition, 2016
Restriction of animal foods and choline may affect plasma trimethylamine-N-oxide (TMAO). In vegetarians, we investigated the association between TMAO concentrations and the strictness of the diet or sex. We also studied the biological variations of TMAO in vegans.Concentrations of plasma TMAO and choline metabolites were measured in 38 vegans and 67 ...
Obeid, Rima   +3 more
openaire   +3 more sources

Associations of Serum Trimethylamine N-oxide and its precursors with colorectal cancer risk in the Prostate, Lung, Colorectal, Ovarian Cancer Screening Trial Cohort

Cancer
Dietary intake influences gut microbiome composition, which in turn may be associated with colorectal cancer (CRC). Associations of the gut microbiome with colorectal carcinogenesis may be mediated through bacterially regulated, metabolically active ...
Doratha A. Byrd   +9 more
semanticscholar   +1 more source

The association between the gut microbiota metabolite trimethylamine N-oxide and heart failure

Frontiers in Microbiology
This systematic review explores the relationship between the gut microbiota metabolite trimethylamine N-oxide (TMAO) and heart failure (HF), given the significant impact of TMAO on cardiovascular health.
Zharkyn Jarmukhanov   +6 more
semanticscholar   +1 more source

Trimethylamin-N-Oxid

2018
G. F. Hoffmann   +2 more
openaire   +1 more source

Trimethylamine‐N‐oxide (TMAO) response to animal source foods varies among healthy young men and is influenced by their gut microbiota composition: A randomized controlled trial

Molecular Nutrition & Food Research, 2017
J. Espín   +8 more
semanticscholar   +1 more source

Gut Microbial Metabolite Trimethylamine N -Oxide Aggravates Pulmonary Hypertension

American Journal of Respiratory Cell and Molecular Biology, 2022
Kai Yang, Haiyang Tang, Jian Wang
exaly  

C3H9NO Trimethylamine N-oxide

2005
G. Graner   +6 more
openaire   +1 more source

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