Results 121 to 130 of about 112,449 (386)

Improved Synthesis of 1,2-Bis(trimethylsilyl)benzenes using Rieke-Magnesium or the Entrainment Method

open access: yes, 2010
1,2-Bis(trimethylsilyl)benzene is the key starting material for the synthesis of efficient benzyne precursors and certain luminescent π-conjugated materials.
Andreas Lorbach   +4 more
semanticscholar   +1 more source

The Chemistry and Biology of the Tetrodotoxin Natural Product Family

open access: yesAngewandte Chemie International Edition, EarlyView.
Tetrodotoxin is best known as the poison of the pufferfish, which is a delicacy in Japanese cuisine. Its toxicity arises from the selective blockage of NaV channels, which is depicted for the NaV1.7 pore, highlighting the DEKA motif, which permeates sodium ions.
Benedikt Nißl   +6 more
wiley   +1 more source

Total Synthesis and Structural Revision of (−)‐Sodagnitin E

open access: yesAngewandte Chemie International Edition, EarlyView.
Malabaricane triterpenoid sodagnitin E is a chromogen found in various toadstools. This work represents the first total synthesis of (−)‐sodagnitin E as well as the first total synthesis of any malabaricane natural product. A Mukaiyama aldol reaction was utilized to perform a convergent synthesis from two enantioselectively synthesized fragments ...
Philipp Schoch, Tanja Gaich
wiley   +1 more source

A practical approach [PDF]

open access: yes, 2020
Kollmeier, Annette Sophie   +1 more
core   +1 more source

Integrated Chemoenzymatic Synthesis of the mRNA Vaccine Building Block N1‐Methylpseudouridine Triphosphate

open access: yesAngewandte Chemie International Edition, EarlyView.
Pseudouridine‐5′‐triphosphate (ΨTP) and its N1‐methylated derivative (m1ΨTP) are crucial components in mRNA vaccine technology. Here, an atom‐economic, high‐yielding biocatalytic route for ΨTP synthesis is presented. A new chemoenzymatic route for m1ΨTP synthesis was developed.
Martin Pfeiffer   +4 more
wiley   +1 more source

Design of Fluorine‐Free Weakly Coordinating Electrolyte Solvents with Enhanced Oxidative Stability

open access: yesAngewandte Chemie International Edition, EarlyView.
Incorporation of silicon is systematically explored as a sustainable strategy to design weakly solvating electrolytes for lithium‐based batteries. After identifying a promising molecular structure via computational screening, coordination spheres and their correlation with electrochemical key performance indicators are compared between electrolyte ...
Lennart Wichmann   +9 more
wiley   +1 more source

Compound oxidized styrylphosphine [PDF]

open access: yes, 1979
A process is described for preparing flame resistant, nontoxic vinyl polymers which contain phosphazene groups and which do not emit any toxic or corrosive products when they are oxidatively degraded.
Paciorek, K. J. L.
core   +1 more source

Expanding the Inositol Pyrophosphate Toolbox: Stereoselective Synthesis and Application of PP‐InsP4 Isomers in Plant Signaling

open access: yesAngewandte Chemie International Edition, EarlyView.
Stereochemically defined inositol pyrophosphate isomers (PP‐InsP4) were synthesized and assigned by NMR spectroscopy using a chiral solvating agent. In the form of isotopically labeled standards, they were applied in CE‐MS‐based profiling of plant extracts and kinase assays, enabling structural reassignment and functional insight into enzymatic ...
Kevin Ritter   +6 more
wiley   +1 more source

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