Results 71 to 80 of about 61,381 (342)

Enabling Aromatic Hydroxylation in a Cytochrome P450 Monooxygenase Enzyme through Protein Engineering

Chemistry – A European Journal, Volume 28, Issue 67, December 1, 2022., 2022
Structural and biochemical data demonstrate that 4‐phenylbenzoic acid binds within the active site of the cytochrome P450 monooxygenase CYP199A4, but no oxidation occurs. Protein engineering and molecular dynamic simulations establish that aromatic oxidation is enabled by a subtle shift of the substrate relative to the heme, thus improving our ...
Tom Coleman, Joel Z. H. Lee, Alicia M. Kirk, Daniel Z. Doherty, Matthew N. Podgorski, Dilshi K. Pinidiya, John B. Bruning, James J. De Voss, Elizabeth H. Krenske, Stephen G. Bell   +9 more
wiley   +1 more source

Separation of mono- and diglycerides by gas-liquid chromatography

Journal of Lipid Research, 1969
The parameters affecting the separation and quantification of trimethylsilyl ethers of mono- and diglycerides have been investigated by gas-liquid chromatography with QF-1 and SE-30 as stationary phases and a flame ionization detector.
Rodney Watts, R. Dils
doaj  

Labile Base‐Stabilized Silyliumylidene Ions. Non‐Metallic Species Capable of Activating Multiple Small Molecules

Chemistry – A European Journal, Volume 28, Issue 70, December 15, 2022., 2022
Various base‐stabilized silyliumylidene ions with different ligands were synthesized. Their behaviour appeared strongly dependent on the type of ligand. Indeed, in contrast to the poorly reactive silyliumylidenes stabilized by strongly donating ligands (DMAP, NHC), the sulfide‐supported one (SMe2) exhibits higher reactivity toward various small ...
Raphaël Nougué, Shintaro Takahashi, Aymeric Dajnak, Eddy Maerten, Antoine Baceiredo, Nathalie Saffon‐Merceron, Vicenç Branchadell, Tsuyoshi Kato   +7 more
wiley   +1 more source

Kinetics and mechanism of vanadium catalysed asymmetric cyanohydrin synthesis in propylene carbonate

Beilstein Journal of Organic Chemistry, 2010
Propylene carbonate can be used as a green solvent for the asymmetric synthesis of cyanohydrin trimethylsilyl ethers from aldehydes and trimethylsilyl cyanide catalysed by VO(salen)NCS, though reactions are slower in this solvent than the corresponding ...
Michael North, Marta Omedes-Pujol
doaj   +1 more source

Synthesis and Functionalization of a 1,2-Bis(trimethylsilyl)-1,2-disilacyclohexene That Can Serve as a Unit of cis-1,2-Dialkyldisilene

Inorganics, 2018
π-Electron compounds that include multiple bonds between silicon atoms have received much attention as novel functional silicon compounds. In the present paper, 1,2-bis(trimethylsilyl)-1,2-disilacyclohexene 1 was successfully synthesized as thermally ...
Naohiko Akasaka, Kaho Tanaka, Shintaro Ishida, Takeaki Iwamoto   +3 more
doaj   +1 more source

Room‐Temperature‐Observable Interconversion Between Si(IV) and Si(II) via Reversible Intramolecular Insertion Into an Aromatic C−C Bond

Chemistry – A European Journal, Volume 28, Issue 69, December 9, 2022., 2022
The synthesis of a new silepin with a sterically encumbered silyl ligand was achieved, which shows a spectral observable equilibrium towards the isomeric acyclic silylene at room temperature. The equilibrium was analyzed by VT NMR and UV/Vis measurements supported by DFT calculations.
Teresa Eisner, Arseni Kostenko, Franziska Hanusch, Shigeyoshi Inoue   +3 more
wiley   +1 more source

Cross-coupling of dissimilar ketone enolates via enolonium species to afford non-symmetrical 1,4-diketones

Beilstein Journal of Organic Chemistry, 2018
Due to their closely matched reactivity, the coupling of two dissimilar ketone enolates to form a 1,4-diketone remains a challenge in organic synthesis.
Keshaba N. Parida, Gulab K. Pathe, Shimon Maksymenko, Alex M. Szpilman   +3 more
doaj   +1 more source

Synthesis and Structures of [(Trimethylsilyl)methyl]sodium and ‐potassium with Bi‐ and Tridentate N‐Donor Ligands

, 2011
[(Trimethylsilyl) methyl] sodium [NaCH2SiMe3] (1) was prepared by a metathesis reaction of [(trimethylsilyl) methyl] lithium [LiCH2SiMe3] with sodium tert-butoxide in n-hexane. Polydentate donors such as N,N,N',N'-tetramethylethylenediamine (TMEDA) and N,
W. Clegg, B. Conway, A. Kennedy, J. Klett, R. Mulvey, Luca Russo   +5 more
semanticscholar   +1 more source

Konkurrenz zwischen unimolekularen Ein‐ und Zwei‐Elektron‐Reaktionen später 3d‐Metallkomplexe [(Me3SiCH2)nM]– (M = Fe, Co, Ni, Cu; n = 2 – 4)

Angewandte Chemie, EarlyView.
Gasphasen‐Fragmentierungsexperimente und theoretische Rechnungen an einer Reihe von Modellkomplexen bestimmen die intrinsischen Neigungen später 3d‐Metalle, Ein‐ oder Zwei‐Elektron‐Reaktionen einzugehen, und decken die für die Selektivität entscheidenden Faktoren auf.
Torben Kühl, Lisa Hetzel, Christopher J. Stein, Konrad Koszinowski   +3 more
wiley   +1 more source

Heavy Chains: Synthesis, Reactivity and Decomposition of Interpnictogen Chains with Terminal Diaryl Bismuth Fragments

Chemistry – A European Journal, Volume 28, Issue 69, December 9, 2022., 2022
Making and breaking chains. Interpnictogen chains have been synthesized, and their decomposition has been studied. It was shown that the compound Ph2BiP(tBu)BiPh2 reacts with the small N‐heterocyclic carbene (Me2IMe) as a “masked phosphinidene” to form Me2IMe=PtBu.
Tobias Dunaj, Carsten von Hänisch
wiley   +1 more source