Results 111 to 120 of about 26,757 (246)

Structural and Dynamical Properties of Nucleic Acid Hairpins Implicated in Trinucleotide Repeat Expansion Diseases

Biomolecules
Dynamic mutations in some human genes containing trinucleotide repeats are associated with severe neurodegenerative and neuromuscular disorders—known as Trinucleotide (or Triplet) Repeat Expansion Diseases (TREDs)—which arise when the repeat number of ...
Feng Pan, Pengning Xu, Christopher Roland, Celeste Sagui, Keith Weninger   +4 more
doaj   +1 more source

The length and location of CAG trinucleotide repeats in the androgen receptor N-terminal domain affect transactivation function [PDF]

, 1994
Nancy L. Chamberlain, Erika D. Driver, Roger L. Miesfeld   +2 more
openalex   +1 more source

Genome-wide survey of D/E repeats in human proteins uncovers their instability and aids in identifying their role in the chromatin regulator ATAD2

iScience, 2022
Summary: D/E repeats are stretches of aspartic and/or glutamic acid residues found in over 150 human proteins. We examined genomic stability of D/E repeats and functional characteristics of D/E repeat-containing proteins vis-à-vis the proteins with poly ...
Shalabh Shukla, Pavlo Lazarchuk, Maria N. Pavlova, Julia M. Sidorova   +3 more
doaj  

Trinucleotide repeat length and progression of illness in Huntington's disease. [PDF]

, 1994
Karl Kieburtz, Marcy E. MacDonald, Chiu-Yang Shih, Andrew Feigin, Kim Steinberg, Kathy Bordwell, Carol Zimmerman, Jayalakshmi Srinidhi, Jenny Sotack, James F. Gusella   +9 more
openalex   +1 more source

Structure and Dynamics of DNA and RNA Double Helices Formed by d(CTG), d(GTC), r(CUG), and r(GUC) Trinucleotide Repeats and Associated DNA-RNA Hybrids. [PDF]

J Phys Chem B, 2023
Fakharzadeh A, Qu J, Pan F, Sagui C, Roland C.   +4 more
europepmc   +1 more source

Diagrammatic approaches to RNA structures with trinucleotide repeats. [PDF]

Biophys J, 2021
Mak CH, Phan ENH.
europepmc   +1 more source

Trinucleotide repeat polymorphism in the androgen receptor gene (AR) [PDF]

, 1992
H.F.B.M. SIeddens, B. A. Oostra, Brinkmann Ao, Jan Trapman   +3 more
openalex   +1 more source

Trinucleotide repeats associated with human disease [PDF]

Nucleic Acids Research, 1997
Triplet repeat expansion diseases (TREDs) are characterized by the coincidence of disease manifestation with amplification of d(CAG. CTG), d(CGG.CCG) or d(GAA.TTC) repeats contained within specific genes. Amplification of triplet repeats continues in offspring of affected individuals, which generally results in progressive severity of the disease and ...
openaire   +3 more sources

Bioinformatics Analysis of the Interaction of miRNAs and piRNAs with Human mRNA Genes Having di- and Trinucleotide Repeats. [PDF]

Genes (Basel), 2022
Belkozhayev A, Niyazova R, Wilson C, Jainakbayev N, Pyrkova A, Ashirbekov Y, Akimniyazova A, Sharipov K, Ivashchenko A.   +8 more
europepmc   +1 more source

Stability of a CTG/CAG Trinucleotide Repeat in Yeast Is Dependent on Its Orientation in the Genome [PDF]

, 1997
Catherine H. Freudenreich, Jeffrey B. Stavenhagen, Virginia A. Zakian   +2 more
openalex   +1 more source