Genotype and phenotype characterisation of Friedreich ataxia mouse models and cells [PDF]
, 2013 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel UniversityFriedreich ataxia (FRDA) is an autosomal recessive neurodegenerative disorder, caused by a GAA repeat expansion mutation within intron 1 of the FXN gene ...
Anjomani Virmouni, Sara
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Diagrammatic approaches to RNA structures with trinucleotide repeats. [PDF]
Biophys J, 2021 Mak CH, Phan ENH.
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Structure and Dynamics of DNA and RNA Double Helices Formed by d(CTG), d(GTC), r(CUG), and r(GUC) Trinucleotide Repeats and Associated DNA-RNA Hybrids. [PDF]
J Phys Chem B, 2023 Fakharzadeh A +4 more
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Analysis of trinucleotide repeats by long-read SMRT sequencing for RE-/FECD-.
, 2019 a. CAG repeat lengths in representative RE-/FECD- sample 663. Repeat count histogram showing two peaks at 19 and 31 repeats agrees well with the results of STR analysis (18 and 30 repeats). b. CAG repeat lengths versus the number of zero-mode waveguides (
Shubham Basu (6920210) +12 more
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Instability and chromatin structure of expanded trinucleotide repeats.
, 2009 Trinucleotide repeat expansion underlies at least 17 neurological diseases. In affected individuals, the expanded locus is characterized by dramatic changes in chromatin structure and in repeat tract length.
Wilson, JH, Dion, V
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Role for CCG-trinucleotide repeats in the pathogenesis of chronic lymphocytic leukemia
, 2001 Chromosome 11q deletions are frequently observed in chronic lymphocytic leukemia (CLL) in association with progressive disease and a poor prognosis. A minimal region of deletion has been assigned to 11q22-q23.
Syndercombe Court, Denise +6 more
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PNA microprobe for label-free detection of expanded trinucleotide repeats. [PDF]
RSC Adv, 2022 Asefifeyzabadi N +5 more
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DNA Sequence Specificity Reveals a Role of the HLTF HIRAN Domain in the Recognition of Trinucleotide Repeats. [PDF]
Biochemistry, 2022 Dusek CO +6 more
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Trinucleotide repeats and neuropsychiatric phenotypes
, 2001 Genetic studies of affective disorders have yielded several chromosomal regions suggestive for linkage. Linkage analysis was performed in five families with unipolar affective disorder, collected from northern Sweden.
Qiu-Ping Yuan (88254)
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Instability of CAG and CTG trinucleotide repeats in Saccharomyces cerevisiae
, 2009 A quantitative genetic assay was developed to monitor alterations in tract lengths of trinucleotide repeat sequences in Saccharomyces cerevisiae. Insertion of (CAG)50 or (CTG)50 repeats into a promoter that drives expression of the reporter gene ADE8 ...
Miret, Juan J. +2 more
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