Results 211 to 220 of about 45,786 (250)

Crystal structure analysis and conformational epitope mutation of triosephosphate isomerase, a mud crab allergen.

Journal of Agricultural and Food Chemistry, 2019
The triosephosphate isomerase (TIM), Scy p 8, is a crab allergen and shows cross-reactivity in shellfish. Here, recombinant Scy p 8 was expressed and its crystal structure was determined at a resolution of 1.8 Å.
Fei Xia, Mengsi Li, Qing-Mei Liu, Meng Liu, Yang Yang, M. Cao, Guixia Chen, T. Jin, Guangming Liu   +8 more
semanticscholar   +1 more source

Medical and Veterinary Importance of the Moonlighting Functions of Triosephosphate Isomerase.

Current protein and peptide science, 2019
Triosephosphate isomerase is the fifth enzyme in glycolysis and its canonical function is the reversible isomerization of glyceraldehyde-3-phosphate and dihydroxyacetone phosphate. Within the last decade multiple other functions, that may not necessarily
Mónica Rodríguez-Bolaños, R. Pérez-Montfort   +1 more
semanticscholar   +1 more source

Unstable triosephosphate isomerase (TPI)

Pathology, 1980
This study was undertaken in the investigation of a child with chronic non-spherocytic haemolytic anaemia. B.C. was born in 1977 of unrelated parents. His father has β-thalassaemia minor. He required an exchange transfusion for neonatal jaundice and subsequently has had persistent anaemia, splenomegaly and intermittent jaundice.
A.C.L. Clark, M.A. Szobolotzky
openaire   +2 more sources

A Metabolic Bypass of the Triosephosphate Isomerase Reaction

Biochemistry, 2008
Triosephosphate isomerase (TIM) catalyzes the interconversion of d-glyceraldehyde 3-phosphate and dihydroxyacetone phosphate, an essential step in glycolytic and gluconeogenic metabolism. To uncover promiscuous isomerases embedded within the Escherichia coli genome, we searched for genes capable of restoring growth of a TIM-deficient bacterium under ...
Kevin K. Desai, Brian G. Miller
openaire   +3 more sources

Immobilized triosephosphate isomerases a comparative study

Applied Biochemistry and Biotechnology, 1992
Pig muscle triosephosphate isomerase was covalently attached to polyacrylamide and silica-based supports possessing carboxylic or aldehyde functional groups or activated with p-benzoquinone. A silica-based support activated with p-benzoquinone proved to be the most advantageous. There were no profound alterations in the catalytic properties as a result
A. Alexin, Bela Szajani, M. Abrahám
openaire   +3 more sources

Triosephosphate Isomerase Deficiency: Predictions and Facts

Journal of Theoretical Biology, 1996
Deficiencies in around 20 enzymes, associated with widely different degrees of severity and complexity, have been identified for human erythrocytes. The fact that glycolysis is crucial for erythrocyte function is reflected by the large number of inherited glycolytic enzymopathies. Triosephosphate isomerase (TPI) deficiency, a rare autosomal disease, is
Beáta G. Vértessy, Ferenc Orosz, Judit Ovádi, Susan R. Hollán, Margit Horányi   +4 more
openaire   +3 more sources

Removal of Triosephosphate, Isomerase from Albumins

Preparative Biochemistry, 1973
Abstract Commercial serum albumin and ovalbumin from a variety of sources contain triosephosphate isomerase activity which can interfere with many enzyme assays and metabolic studies. A simple procedure is described for the removal of this contaminant by preparative electrophoresis or electrofocus-ing.
Robert W. Gracy, B. G. Harris, D. W. Porter   +2 more
openaire   +3 more sources

Light‐inducible flux control of triosephosphate isomerase on glycolysis in Escherichia coli

Biotechnology and Bioengineering, 2019
An engineering tool for controlling flux distribution on metabolic pathways to an appropriate state is highly desirable in bioproduction. An optogenetic switch, which regulates gene expression by light illumination is an attractive on/off switchable ...
Sachie Senoo, S. T. Tandar, Sayaka Kitamura, Yoshihiro Toya, H. Shimizu   +4 more
semanticscholar   +1 more source

Nuerological finding in triosephosphate isomerase deficiency

Annals of Neurology, 1985
AbstractTwo siblings with hemolytic anemia caused by triosephosphate isomerase deficiency developed a progressive neurological syndrome featuring dystonic movements, tremor, pyramidal tract signs, and evidence of spinal motor neuron involvement. Intelligence was unaffected.
Jean Aicardi, R. Rosa, Bwee Tien Poll-The, Robert Girot   +3 more
openaire   +3 more sources

Triosephosphate Isomerase and Filamin C Share Common Epitopes as Novel Allergens of Procambarus clarkii.

Journal of Agricultural and Food Chemistry, 2017
Triosephosphate isomerase (TIM) is a key enzyme in glycolysis and has been identified as an allergen in saltwater products. In this study, TIM with a molecular mass of 28 kDa was purified from the freshwater crayfish (Procambarus clarkii) muscle.
Yang Yang, Yong-xia Zhang, Meng Liu, S. Maleki, Ming-Li Zhang, Qing-Mei Liu, M. Cao, W. Su, Guangming Liu   +8 more
semanticscholar   +1 more source