Structural analysis on mutation residues and interfacial water molecules for human TIM disease understanding [PDF]
10.1186/1471-2105-14-S16-S11BMC Bioinformatics14SUPPL16 ...
A Pekrun+44 more
core +3 more sources
In Silico Prediction of T and B Cell Epitopes of Der f 25 in Dermatophagoides farinae
The house dust mites are major sources of indoor allergens for humans, which induce asthma, rhinitis, dermatitis, and other allergic diseases. Der f 25 is a triosephosphate isomerase, representing the major allergen identified in Dermatophagoides farinae.
Xiaohong Li+5 more
doaj +1 more source
Cartilage and subchondral bone communicate with each other through material and signal exchanges. However, direct evidence provided by experimental studies on their interactions is insufficient.
Wei Jieya+7 more
doaj +1 more source
Triosephosphate isomerase (TPI) catalyzes the interconversion of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (G3P). This reaction is required for glycolysis and gluconeogenesis, and tpi has been predicted to be essential for growth ...
Carolina Trujillo+5 more
doaj +1 more source
Triosephosphate isomerase deficiency: Facts and doubts [PDF]
Many glycolytic enzymopathies have been described that manifest clinically as chronic hemolytic anemia. One of these, triosephosphate isomerase (TPI) deficiency, is unique among the glycolytic enzyme defects since it is associated with progressive neurological dysfunction and frequently with childhood death.
Judit Oláh, Judit Ovádi, Ferenc Orosz
openaire +2 more sources
Proteomics of canine lymphoma identifies potential cancer-specific protein markers [PDF]
Purpose: Early diagnosis of cancer is crucial for the success of treatment of the disease, and there is a need for markers whose differential expression between disease and normal tissue could be used as a diagnostic tool.
Alexander, Hannah, 1947-+8 more
core +1 more source
Artificial Photosynthesis Would Unify the Electricity-Carbohydrate-Hydrogen Cycle for Sustainability [PDF]
Sustainable development requires balanced integration of four basic human needs – air (O2/CO2), water, food, and energy. To solve key challenges, such as CO2 fixation, electricity storage, food production, transportation fuel production, water ...
Yi-Heng Percival Zhang
core +2 more sources
Loop Motion in Triosephosphate Isomerase Is Not a Simple Open and Shut Case.
Conformational changes are crucial for the catalytic action of many enzymes. A prototypical and well-studied example is loop opening and closure in triosephosphate isomerase (TIM), which is thought to determine the rate of catalytic turnover in many ...
Qinghua Liao+7 more
semanticscholar +1 more source
Explicit consideration of topological and parameter uncertainty gives new insights into a well-established model of glycolysis [PDF]
Previous models of glycolysis in the sleeping sickness parasite Trypanosoma brucei assumed that the core part of glycolysis in this unicellular parasite is tightly compartimentalized within an organelle, the glycosome, which had previously been shown to ...
Achcar+30 more
core +1 more source
Identification of liver protein targets modified by tienilic acid metabolites using a two-dimensional Western blot-mass spectrometry approach [PDF]
International audienceA combined approach based on two-dimensional electrophoresis-immuno-blotting and nanoliquid chromatography coupled on-line with electrospray ionization mass spectrometry (nLC-MS/MS) was used to identify proteins modified by a ...
Dansette, Patrick,+2 more
core +2 more sources