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Harnessing cholesterol uptake of malaria parasites for therapeutic applications. [PDF]
EMBO Mol MedFraser M +10 more
europepmc +1 more source
FLUFF-BALL, a Fuzzy Superposition and QSAR Technique - Towards an Automated Computational Detection of Biologically Active Compounds Using Multivariate Methods (FLUFF-BALL, sumea superpositio ja QSAR-menetelmä - Tavoitteena bioaktiivisten molekyylien automaattinen tietokoneavusteinen tunnistaminen hyödyntäen monimuuttujamenetelmiä) [PDF]
Korhonen, Samuli-Petrus
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Orally active amino functionalized antimalarial 1,2,4-trioxanes
Bioorganic and Medicinal Chemistry Letters, 2004AbstractFor Abstract see ChemInform Abstract in Full Text.
Chandan, Singh +2 more
exaly +4 more sources
Medicinal research reviews (Print), 2023
The demand for novel, fast‐acting, and effective antimalarial medications is increasing exponentially. Multidrug resistant forms of malarial parasites, which are rapidly spreading, pose a serious threat to global health.
Monika Shukla +6 more
semanticscholar +1 more source
The demand for novel, fast‐acting, and effective antimalarial medications is increasing exponentially. Multidrug resistant forms of malarial parasites, which are rapidly spreading, pose a serious threat to global health.
Monika Shukla +6 more
semanticscholar +1 more source
Recent advances in the synthesis and antimalarial activity of 1,2,4-trioxanes.
Bioorganic chemistry (Print), 2023The increasing resistance of various malarial parasite strains to drugs has made the production of a new, rapid-acting, and efficient antimalarial drug more necessary, as the demand for such drugs is growing rapidly.
Komal Rathi +5 more
semanticscholar +1 more source
Bioorganic & Medicinal Chemistry Letters, 2023
Following the economic and social state of humanity, Malaria is categorized as one of the life-threatening illness epidemics in under developed countries.
Priyanka Yadav +6 more
semanticscholar +1 more source
Following the economic and social state of humanity, Malaria is categorized as one of the life-threatening illness epidemics in under developed countries.
Priyanka Yadav +6 more
semanticscholar +1 more source
Journal of Organic Chemistry, 2021
A novel protocol for the preparation of non-symmetrical 1,2,4,5-tetraoxanes and 1,2,4-trioxanes, promoted by the heterogeneous silica sulfuric acid (SSA) catalyst, is reported.
Patrícia S. M. Amado +4 more
semanticscholar +1 more source
A novel protocol for the preparation of non-symmetrical 1,2,4,5-tetraoxanes and 1,2,4-trioxanes, promoted by the heterogeneous silica sulfuric acid (SSA) catalyst, is reported.
Patrícia S. M. Amado +4 more
semanticscholar +1 more source
Bioorganic & Medicinal Chemistry Letters, 2021
A new series of 1,2,4-trioxanes9a1-a4,9b1-b4, 10-13and9c1-c4were synthesized and evaluated against multidrug-resistantPlasmodium yoelii nigeriensisin Swiss mice via oral and intramuscular (i.m.) routes.
Manvika Karnatak +8 more
semanticscholar +1 more source
A new series of 1,2,4-trioxanes9a1-a4,9b1-b4, 10-13and9c1-c4were synthesized and evaluated against multidrug-resistantPlasmodium yoelii nigeriensisin Swiss mice via oral and intramuscular (i.m.) routes.
Manvika Karnatak +8 more
semanticscholar +1 more source
Organic and biomolecular chemistry, 2021
Photocatalytic syntheses of quinoline-2(1H)-ones, isoquinoline-1(2H)-ones and 1,2,4-trioxanes were achieved by selective photo-induced electron transfer (PET) and energy transfer (EnT), respectively, by chlorophyll under visible light irradiation ...
S. Banu +4 more
semanticscholar +1 more source
Photocatalytic syntheses of quinoline-2(1H)-ones, isoquinoline-1(2H)-ones and 1,2,4-trioxanes were achieved by selective photo-induced electron transfer (PET) and energy transfer (EnT), respectively, by chlorophyll under visible light irradiation ...
S. Banu +4 more
semanticscholar +1 more source