Antimalarial activity of artemisinin (qinghaosu) and related trioxanes: mechanism(s) of action.
Publisher Summary Malaria is one of the most deadly infectious diseases known to mankind. The species of Plasmodium that cause malaria can develop resistance to chemotherapeutic drugs that is going in recent times.
J. Cumming, P. Ploypradith, G. Posner
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Photocatalytic Synthesis of para-Peroxyquinols: Total Synthesis of (±)-Stemenone B and (±)-Parvistilbine B. [PDF]
Carson MC, Orzolek BJ, Kozlowski MC.
europepmc +1 more source
Multigram Synthesis of Trioxanes Enabled by a Supercritical CO2 Integrated Flow Process
Lingqiao Wu +8 more
semanticscholar +1 more source
Several trioxanes were synthesized through perhydrolysis of an allylic epoxide followed by ketal exchange with a proper dimethyl ketal.
Yun Li, S. Wittlin, Yikang Wu
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Closed Aromatic Tubes-Capsularenes. [PDF]
Pavlović RZ +13 more
europepmc +1 more source
Structural characterization of strained oxacycles by 13C NMR spectroscopy [PDF]
The 1H and 13C NMR data of a series of epoxy-and epidioxy-bridged tetrahydropyran derivatives containing the same basic carbon skeleton, are reported. 13C NMR spectroscopy was shown to be useful for structural determination of both substructures allowing
la Venia, Agustina +2 more
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Lewis Acids and Heteropoly Acids in the Synthesis of Organic Peroxides. [PDF]
Yaremenko IA +5 more
europepmc +1 more source
Inhibition of Yeast Hexokinase by the Antimalarial Drug Artemisinin: Probing Mechanism of Action with a Model Enzyme [PDF]
A leading infectious cause of death, malaria threatens approximately half of the world\u27s population, and drug-resistant strains of Plasmodium falciparum have created immense difficulty in chemotherapy of the disease.
Spence, Jennifer S.
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The anti-tumour activity and mode of action of artesunate and dihydroartemisinin (alone and in combination with aspirin) against human leukaemia HL-60 and colorectal HT-29-AK cancer cells [PDF]
Despite the considerable progress in cancer research which has been translated into better cancer care and decreased overall mortality rates in the last decade for numerous cancers, colorectal carcinoma (CRC) and leukaemia remain still one of the ...
Maryniak, Lidia Barbara
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