Results 71 to 80 of about 2,928 (218)

Novel halogenated arylvinyl-1,2,4 trioxanes as potent antiplasmodial as well as anticancer agents: Synthesis, bioevaluation, structure-activity relationship and in-silico studies.

open access: yesEuropean journal of medicinal chemistry, 2021
Mohit K. Tiwari   +8 more
semanticscholar   +1 more source

Antimalarial activity of artemisinin (qinghaosu) and related trioxanes: mechanism(s) of action.

open access: yesAdvances in Pharmacology, 1997
Publisher Summary Malaria is one of the most deadly infectious diseases known to mankind. The species of Plasmodium that cause malaria can develop resistance to chemotherapeutic drugs that is going in recent times.
J. Cumming, P. Ploypradith, G. Posner
semanticscholar   +1 more source

Multigram Synthesis of Trioxanes Enabled by a Supercritical CO2 Integrated Flow Process

open access: yesOrganic Process Research & Development, 2021
Lingqiao Wu   +8 more
semanticscholar   +1 more source

ACCESS TO SOME UV CHROMOPHORE-CONTAINING ANTIMALARIAL TRIOXANES USING HYDROGEN PEROXIDE AS SOURCE OF THE PEROXY BONDS

open access: yes, 2012
Several trioxanes were synthesized through perhydrolysis of an allylic epoxide followed by ketal exchange with a proper dimethyl ketal.
Yun Li, S. Wittlin, Yikang Wu
semanticscholar   +1 more source

Closed Aromatic Tubes-Capsularenes. [PDF]

open access: yesAngew Chem Int Ed Engl, 2022
Pavlović RZ   +13 more
europepmc   +1 more source

Structural characterization of strained oxacycles by 13C NMR spectroscopy [PDF]

open access: yes, 2011
The 1H and 13C NMR data of a series of epoxy-and epidioxy-bridged tetrahydropyran derivatives containing the same basic carbon skeleton, are reported. 13C NMR spectroscopy was shown to be useful for structural determination of both substructures allowing
la Venia, Agustina   +2 more
core   +1 more source

Lewis Acids and Heteropoly Acids in the Synthesis of Organic Peroxides. [PDF]

open access: yesPharmaceuticals (Basel), 2022
Yaremenko IA   +5 more
europepmc   +1 more source

Inhibition of Yeast Hexokinase by the Antimalarial Drug Artemisinin: Probing Mechanism of Action with a Model Enzyme [PDF]

open access: yes, 2009
A leading infectious cause of death, malaria threatens approximately half of the world\u27s population, and drug-resistant strains of Plasmodium falciparum have created immense difficulty in chemotherapy of the disease.
Spence, Jennifer S.
core   +2 more sources

The anti-tumour activity and mode of action of artesunate and dihydroartemisinin (alone and in combination with aspirin) against human leukaemia HL-60 and colorectal HT-29-AK cancer cells [PDF]

open access: yes, 2016
Despite the considerable progress in cancer research which has been translated into better cancer care and decreased overall mortality rates in the last decade for numerous cancers, colorectal carcinoma (CRC) and leukaemia remain still one of the ...
Maryniak, Lidia Barbara
core   +1 more source

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