Results 181 to 190 of about 289,605 (341)
Multicontrast MRI-based radiomics for the prediction of pathological complete response to neoadjuvant chemotherapy in patients with early triple negative breast cancer
, 2021 Angéline Nemeth, Pierre Chaudet, Benjamin Leporq, Pierre-Étienne Heudel, Fanny Barabas, Olivier Trédan, Isabelle Treilleux, A. Coulon, F. Pilleul, Olivier Beuf +9 moreopenalex +2 more sourcesHepatocyte Mettl3 Deficiency Drives Primary Sclerosing Cholangitis and Liver Fibrosis via Cholangiocyte‐Macrophage Crosstalk
Advanced Science, EarlyView.Schematic illustration demonstrating that hepatic Mettl3 depletion significantly elevates the secretion of Mif and Csf1. This elevation facilitates Trem2+ macrophage infiltration and triggers cholangiocyte remodeling through the Spp1‐Cd44 interaction, resulting in spontaneous PSC development in vivo.Wenting Pan, Yuting Yong, Yuanshuai Li, Gaona Shi, Min Zhang, Lingfei Wan, Yue Zhao, Wenling Zhan, Yanli Lin, Qiaozhen Qin, Xupeng Chen, Yanli Ni, Haixu Chen, Wenzai Shi, Xiaomeng Guo, Juan Chen, Shuchen Liu, Youliang Wang, Bing Liu, Xinlong Yan +19 morewiley +1 more sourceUnraveling the Pivotal Network of Ultrasound and Somatic Mutations in Triple-Negative and Non-Triple-Negative Breast Cancer
, 2023 Yunxia Huang, Yi Guo, Qin Xiao, Shuyu Liang, Qiang Yu, Lang Qian, Jin Zhou, Le Jian, Yu‐Chen Pei, Lei Wang, Cai Chang, Sheng Chen, Shichong Zhou +12 moreopenalex +2 more sourcesStress‐Programmed Immune Niches Fuel TNFR2+ Treg Activation and Drive Neoadjuvant Chemotherapy Resistance in Breast Cancer
Advanced Science, EarlyView.Single‐cell sequencing reveals stress‐programmed immune states driving TNFα–TNFR2–mediated Treg activation and therapy resistance in breast cancer, while targeting this axis restores antitumor immunity. ABSTRACT
The tumor microenvironment (TME) harbors diverse immune cell states that shape therapeutic outcomes in breast cancer.Zhibo Shao, Xuliren Wang, Han Zhu, Ling Yao, Qi Zhang, Zihan Zhai, Xinyi Lv, Xinyuan Xia, Yi Zhang, Xinya Lu, Xinyi Quan, Jiawen Yang, Xinwei Li, Jieyi Dong, Zhi‐ming Shao, Ruoxi Wang, Bingqiu Xiu, Jiong Wu, Sheng Chen +18 morewiley +1 more sourceNanoarchaeosomes for synergistic photochemotherapy in triple-negative breast cancer. [PDF]
Sci RepBasha SS, Thomas S, Ariraman S, Babu RS, Santhosh PB, Stoychev L, Genova J, Daskalova A, Bhoir B, Selvaraj V, Sudhakar S. +10 moreeuropepmc +1 more sourceBRCA mutations among triple negative breast cancer without family history of breast and ovarian cancer: The Modena family cancer clinic experience
, 2019 Eleonora Molinaro, Marta Venturelli, Angela Toss, Claudia Piombino, Elena Barbieri, Luigi Marcheselli, Isabella Marchi, Enrico Tagliafico, Stefano Cascinu, Laura Cortesi +9 moreopenalex +2 more sourcesTriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy
Advanced Science, EarlyView.We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor Xinyu Peng, Jiaxing Huang, Shengnan Lv, Jian Zhang, Liangliang Zhang, Huan Liu, Yan Liu, Zhen‐An Qiao, Feng Wei, Bao‐Lian Su +9 morewiley +1 more sourceSupplementary Table S2 from An Olive Oil–Based High-Fat Diet Promotes Obesity-Driven Metastasis of Triple-Negative Breast Cancer
Anthony M. Avellino, Xingshan Jiang, Michael Lee, Jianyu Yu, Shanshan Liu, Xiaochun Han, Jerry Li, Jonathan Shilyansky, Zhaohua Wang, Melissa Curry, Yiqin Xiong, Ingrid M. Lizarraga, Yi Huang, Sonia L. Sugg, Jiaqing Hao, Bing Li +15 moreopenalex +1 more source
