Results 181 to 190 of about 126,042 (242)

Real-world outcome of neoadjuvant therapy with or without pembrolizumab for triple-negative breast cancer. [PDF]

Acta Oncol
Maunu M, Lähteenmaa J, Karihtala P, Tuohinen S, Laaksolilja J, Laaksolilja J, Ståhls A, Meretoja T, Mattson J.   +8 more
europepmc   +1 more source

ZBTB21 Is a Dual Suppressor of Pyroptosis and MHC‐I Antigen Presentation That Promotes Tumor Immune Evasion

Advanced Science, EarlyView.
ZBTB21 is a transcription factor that epigenetically suppresses pyroptosis and MHC‐I antigen presentation, enabling tumor immune evasion. Genetic ablation of ZBTB21 activates pyroptotic cell death and enhances antigen presentation, recruiting CD8+ T cells to overcome immune checkpoint blockade resistance.
Lei Zhao, Linlin Sheng, Jianhao Qiu, Junjie Ma, Kai Jin, Binggong Zhao, Tianrun Miao, Jing Chen, Yehong Li, Zhan Zhang, Dongfeng Sun, Yongmeng Li, Hui Tian   +12 more
wiley   +1 more source

ZMIZ2/MCM3 Axis Participates in Triple-Negative Breast Cancer Progression. [PDF]

Oncol Res
Zou X, Sun M, Jiang X, Yu J, Li X, Nie B.   +5 more
europepmc   +1 more source

A Metal‐Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer

Advanced Science, EarlyView.
A metal‐free carbon monoxide (CO) prodrug, CO‐116, delivers controlled systemic CO without inhalation. CO suppresses the HRG1–heme axis, reducing intracellular heme availability. Attenuation of this pathway inhibits metastatic progression in pancreatic and triple‐negative breast cancer models.
Tiantian Zhang, Xiang Chen, Xiaoxiao Yang, Muskan Gori, Rohit Kumar Varshnaya, Dongning Liu, Cheryl Zhang, Michelle Yi Qin Chen, Zhengming Chen, George Zhang, Erika Patel, Qiyue Mao, Tan A. Ince, Chalet Tan, Binghe Wang, Yi‐Chieh Nancy Du   +15 more
wiley   +1 more source

Multi‐Organelle Stress‐Induced Paraptosis by a ROS‐Amplifying Nanocatalyst for Enhanced Cancer Immunotherapy

Advanced Science, EarlyView.
The engineered TF‐Fe@LC nanoplatform programs paraptotic death via multipath ROS amplification that disrupts redox homeostasis, provoking mitochondrial dysfunction, autophagic blockade, and ER stress. This caspase‐independent process elicits robust immunogenic cell death, combining with αPD‐L1 to activate systemic CD8+ T‐cell immunity and suppress ...
Zhe Yu, Haozhe Ren, Hua Li, Jinghan Zhao, Miaomiao Cao, Tian Tang, Youbei Qiao, Liting Chen, Tiehong Yang, Hong Wu   +9 more
wiley   +1 more source

Management Options in Triple-Negative Breast Cancer

Breast Cancer: Basic and Clinical Research, 2011
Christina A. Minami, Debra U. Chung, Helena R. Chang   +2 more
doaj  

Modelling the metastatic immune microenvironment in triple-negative breast cancer. [PDF]

Breast Cancer Res
de la Fuente LR, Law AMK, Rangel-Sanchez L, Venhuizen J, Steffan F, Castillo L, Anderson RL, Valdes-Mora F, Gallego-Ortega D.   +8 more
europepmc   +1 more source