Results 191 to 200 of about 289,605 (341)
Schematic illustration of the proposed model. Primary CAFs are isolated from fresh human GBM specimens according to established protocols. GLUL is essential for pro‐angiogenic capacity of CAFs through its impact on the PI3K/AKT pathway. GLUL enhances the pro‐angiogenic capacity of CAFs, driving aberrant tumor vasculature that fuels tumor growth ...
Qing Zhang +4 more
wiley +1 more source
Editorial: Deciphering cell-cell interactions in triple-negative breast cancer. [PDF]
Yang X, Zhu L, Li X, Du Y.
europepmc +1 more source
Upregulated TRMT6 forms aberrant hypermethylation of a specific tRNA pool and serves as a predictor of poor prognosis in TNBC. This m1A modification in tRNAs enhances translation of FTH1 and FTL, reducing the pool of bioavailable Fe2⁺. Reduced Fe2+ availability impairs RSL3‐induced lipid peroxidation and tumor progression.
Yuqing Lei +12 more
wiley +1 more source
Expression and clinical significance of TEM8 protein in triple-negative breast cancer. [PDF]
Huang F, Liu Y, Ren H, Qiu H, Jiang Y.
europepmc +1 more source
Extracellular vesicles (EVs) released from TGF‐β‐activated CAFs are enriched with ECM proteins such as TSG6 and THBS1, which facilitate their binding to recipient cell membranes. This EV–cell interaction promotes the clustering of CD44 and TGF‐β receptors on the target cell surface, thereby potentiating TGF‐β signaling activity. This study highlights a
Chao Li +7 more
wiley +1 more source
ZMIZ2/MCM3 Axis Participates in Triple-Negative Breast Cancer Progression. [PDF]
Zou X +5 more
europepmc +1 more source
Patient-Derived Xenografts of Triple-Negative Breast Cancer Enable Deconvolution and Prediction of Chemotherapy Responses [PDF]
Jonathan T. Lei +36 more
openalex +1 more source

