Results 201 to 210 of about 6,967,236 (252)

Inflammatory indexes as prognostic biomarkers in advanced triple negative breast cancer patients. [PDF]

Front Oncol
Gianni C, Scarpi E, Blondeaux E, Palleschi M, Merloni F, Gasperoni L, Puglisi F, Collovà E, Pugliese P, Cognetti F, Giannubilo I, Ruelle T, Del Mastro L, Bighin C, Musolino A, De Giorgi U.   +15 more
europepmc   +1 more source

Space Jam‐Ming: Generating Interstitial Space Using Fragmented Granular GelMA to Investigate Novel Paradigms of Cancer Metastasis

Advanced Science, EarlyView.
Microgels enable independent control of stiffness and interstitial space, overcoming limitations of conventional 3D hydrogels. Using fragmented gelatin methacryloyl microgels, we show that stiffness does not restrict non‐metastatic breast cancer growth, contrary to bulk hydrogels, and reveal the role of adherent‐to‐suspension transition in cancer ...
Danielle Vahala, Zhuang Min Lee, Sebastian E. Amos, Dong Woo Son, Jong Hwa Byun, Farzan Navaeipour, Jiayue Li, Kai L. Metzner, Ji Hoon Jeong, Juyeon Kim, Yongsung Hwang, Brendan F. Kennedy, Khoon S. Lim, Hee Seung Lee, Hyun Woo Park, Yu Suk Choi   +15 more
wiley   +1 more source

Metastasis of triple negative breast cancer is regulated by a targetable miR-342-E2F network. [PDF]

EMBO Mol Med
Arnet VK, Johnstone CN, Redvers RP, Chambers CA, Pillman KA, Toubia J, Lumb R, Dredge BK, Bert AG, Hackett-Jones E, Pinweha P, Bracken JM, Deshpande S, Price ZK, Ortiz M, Scheer KG, Rajpal J, Geiger AB, Roslan S, Li X, O'Toole S, Beilharz TH, Bracken CP, Khew-Goodall Y, Goodall GJ, Anderson RL, Gregory PA.   +26 more
europepmc   +1 more source

Ecotypes of triple-negative breast cancer in response to chemotherapy. [PDF]

Nature
Yan Y, Lin Y, Kumar T, Bai S, Thennavan A, Li J, Sei E, Tran T, Hu M, Rao M, Tang C, He S, Casasent A, Ravenberg E, Rauch GM, Clayborn AR, Tripathy D, Thompson A, Lim B, Huo L, Moulder S, Yam C, Navin N.   +22 more
europepmc   +1 more source

Cancer‐Associated Fibroblasts Promote Glucose Metabolic Reprogramming and Progression of Triple‐Negative Breast Cancer via Exosomal circFAD104‐Mediated Intercellular Communication

Advanced Science, EarlyView.
CAF‐derived exosomes deliver circFAD104 into TNBC cells, where it acts as a molecular scaffold that bridges the E3 ligase MARCHF8 and PGM1, promoting MARCHF8‐mediated K48‐linked ubiquitination and proteasomal degradation of PGM1. Loss of PGM1 redirects glucose‐phosphate flux from glycogen synthesis toward glycolysis, thereby driving stemness, EMT, and ...
Lei Wang, Xiaoyan Li, Yiran Liang, Yifei Wang, Yuhan Jin, Jianing Wang, Dan Luo, Yuxia Yang, Jingze Yang, Yaming Li, Tong Chen, Dianwen Han, Zekun Wang, Wenjing Zhao, Bing Chen, Lijuan Wang, Qifeng Yang   +16 more
wiley   +1 more source

Triple-negative breast cancer, pregnancy, and HLA alloreactivity: a cause for concern? [PDF]

Front Oncol
Crestani Morassutti G, Zanetti M.
europepmc   +1 more source

AI‐Powered, Temperature‐Resolved Centrifugal Microfluidics for Rapid 3D Phase‐Diagram Generation of Biomolecular Condensates

Advanced Science, EarlyView.
By merging centrifugal microfluidics, precise temperature control, and AI image recognition, T‐PhaseMap transforms biomolecular condensate phase mapping into a rapid, temperature‐resolved workflow. It generates 3D composition–temperature phase diagrams within 30 min, resolves four phase states, and uncovers temperature‐dependent heparin sodium ...
Jiashuo Li, Pengjie Li, Kaiting Zhang, Yongqi Guo, Peng Chen, Bi‐Feng Liu, Yiwei Li   +6 more
wiley   +1 more source

GNG12 overexpression inhibits triple-negative breast cancer cell proliferation, migration, and invasion. [PDF]

Sci Rep
Shan BF, Zhao L, Hu T, Xu JH, Zeng TX, Tang JM, Yu B.   +6 more
europepmc   +1 more source

DLST Succinylation‐Mediated Mitochondrial Metabolic Remodeling and Cuproptosis Resistance Promote Malignant Progression of Lung Adenocarcinoma

Advanced Science, EarlyView.
The DLST K409 succinylation mediated by CPT1A promotes OXPHOS and redox homeostasis through regulating enzyme activity, thereby promoting the malignant progression of LUAD. Notably, the succinylation of DLST can enhance the cuproptosis resistance by inhibiting its lipoylation.
Xuanxuan Li, Peijun Zhou, Xingzhi Peng, Qixin Liu, Wenhui Zeng, Rui Wang, Liangfang Shen, Jinwu Peng, Qin Zhou, Lifang Yang   +9 more
wiley   +1 more source

Cepharanthine inhibits lysosomes and induces apoptosis in triple‑negative breast cancer cells. [PDF]

Mol Med Rep
Li J, Zhou S, Wang Y, Ou G, Yang D, Shen L.   +5 more
europepmc   +1 more source