Results 211 to 220 of about 6,967,236 (252)

Type I collagen promotes triple-negative breast cancer progression through a UBE2V1-ACSL5 regulatory axis. [PDF]

Front Oncol
Liu L, Wang Y, You H, Wang C, Yang X, Zhang F, Wu D, Ning X, Qian Z, Jiang Y, Zhang Y, Zhao X, Han T.   +12 more
europepmc   +1 more source

Radiation‐Triggered Chemokine‐Secreting Probiotics for Boron Neutron Capture Therapy Based Radioimmunotherapy

Advanced Science, EarlyView.
Engineered Escherichia coli Nissle 1917 with a tannic acid‐mediated BPA coating enables tumor‐targeted boron delivery for BNCT. The low‐level incidental radiation generated during BNCT activate a RecA‐driven circuit to induce CXCL10, while radiation‐enhanced bacterial colonization triggers in situ vaccination and systemic antitumor immunity.
Yang Liu, Yuzhong Qian, Shaobo Huang, Bingbing Li, Yue Yu, Xiang Cheng, Chang Chen, Jiheng Wang, Maosong Yang, Lizheng Liang, Xiancai Meng, Zhigang Liu   +11 more
wiley   +1 more source

Combine antibody-drug conjugate with cmLumiOpto for triple-negative breast cancer treatment. [PDF]

Cell Rep Med
Varadkar T, Zhou ZZ, Si Y, Zhang J, Du Z, Khanal AG, Chowdhury S, Tsaliki C, Zhou L, Liu XM.   +9 more
europepmc   +1 more source

FOXP1 Knockdown Reprograms Th9 CAR‐T Cells to Overcome Antigen Escape

Advanced Science, EarlyView.
FOXP1 knockdown enhances Th9 CAR‐T cell function by promoting IL‐9 production, effector activation, and reduced exhaustion. Reprogrammed Th9 CAR‐T cells strengthen direct tumor killing and activate endogenous antitumor immunity through dendritic cells and CD8+ T cells, thereby suppressing both antigen‐positive and antigen‐loss tumor growth and ...
Yihan Zhu, Xingwei Xie, Xiaohuan Wu, Suidong Ouyang, Yang Zhou, Kang Wen, Yutong Zhong, Yuyang Chen, Handuo Wang, Yuan Gao, Ling Jiang, Hui Li, Wenli Zhao, Abai Xu, Enguang Bi   +14 more
wiley   +1 more source

Triple-negative breast cancer: current understanding and future perspectives. [PDF]

Explor Target Antitumor Ther
Alobaidi A, Rai V.
europepmc   +1 more source

Leveraging Microphysiological Systems to Facilitate Neutrophil‐Based Cancer Immunotherapy

Advanced Science, EarlyView.
Microphysiological systems are emerging as powerful human‐relevant platforms for studying neutrophil biology in cancer. Current applications of spheroids, organoids, and organ‐on‐a‐chip models are reviewed, together with future opportunities in behaviorome profiling, multi‐omics integration, personalized medicine, immune crosstalk, and multi‐organ ...
Shuai Shao, Markus Isfeld Diehl, Caroline N. Jones   +2 more
wiley   +1 more source

A Ruthenium-BODIPY Photosensitizer for Light-Triggered Apoptosis in Triple-Negative Breast Cancer Cells. [PDF]

Inorg Chem
Wang TH, Lin CH, Sim EZ, Cai-Syaun Wu M, Hau-Ting Wei J, Huang WT, Yu-Syun Fan R, Pan SC, Sangeeta, Ganguly R, Kong KV, Ong TG.   +11 more
europepmc   +1 more source

Dual‐Target Nectin‐4/FAP Heterobivalent Probe 68Ga/177Lu‐FZ‐NF‐1 for Triple‐Negative Breast Cancer: Preclinical Theranostic Evaluation and First‐in‐Human Translation

Advanced Science, EarlyView.
A novel hetero‐bivalent agent, 68Ga/177Lu‐FZ‐NF‐1, concurrently targets Nectin‐4 and FAP in triple‐negative breast cancer. It yields significant preclinical tumor regression and clinically identifies additional metastatic lesions missed by 18F‐FDG PET, demonstrating promising theranostic potential for personalized management.
Ye Li, Li Sun, Xiaoyu Pan, Shuyi Lin, Dongliang Wang, Jianping Zhang, Fengshuang Qiu, Bin Zhu, Lingzhou Zhao, Fengsheng Zhang, Liyan Bai, Bingxin Gu, Xiaoping Xu, Shaoli Song   +13 more
wiley   +1 more source

Neoadjuvant chemotherapy in women with triple-negative breast cancer: real world results from Western Kenya. [PDF]

Oncologist
Rangoonwala HI, Busakhala N, Kiprono H, Sitienei L, Chesori E, Niemeyer K, Sabul W, Opakas J, Ngelel A, Pabon-Rodriguez F, Keitany K, Melly E, Hunter-Squires J, Miller KD, Kisilu N, Loehrer PJ, Morgan JS.   +16 more
europepmc   +1 more source