Results 221 to 230 of about 287,154 (333)

Adjuvant Chemotherapy in Lymph Node-Negative, T1 Triple-Negative Breast Cancer. [PDF]

Cancer Med
Anampa JD, Alvarez Soto A, Jimenez RB, Obeng-Gyasi S, Xue X.   +4 more
europepmc   +1 more source

5′tRF‐GlyGCC Promotes Breast Cancer Progression via LDHA‐Mediated Glycolysis and Macrophage Polarization

Advanced Science, EarlyView.
5’tRF‐GlyGCC promotes breast cancer malignancy by binding to LDHA. This interaction, facilitated by FGFR1 and LDHA phosphorylation, enhances glycolysis. Additionally, 5’tRF‐GlyGCC/LDHA signaling recruits and polarizes macrophages into a pro‐tumor M2 state via CCL7, thus remodeling the tumor microenvironment.
Cheng Yi, Yunqing Lu, Xing Chang, Ying Wang, Jiawang Zhou, Guoyou Xie, Lijun Tao, Zhaotong Wang, Yifan Tian, Lihong Wang, Feng Tang, Yijing Zheng, Xinchen Yue, Jinping Lei, Xiansong Wang, Lichen Ge, Zhuojia Chen, Hongsheng Wang   +17 more
wiley   +1 more source

Understanding the role of neighborhood deprivation in racial disparities in triple-negative breast cancer. [PDF]

Cancer
Barber LE, Maliniak ML, Miller-Kleinhenz JM, Moubadder L, Smith-Graziani D, Switchenko JM, Ward KC, McCullough LE.   +7 more
europepmc   +1 more source

Characterizing PALB2 intragenic duplication breakpoints in a triple-negative breast cancer case using long-read sequencing [PDF]

I Ban, Alice Chabert, Thomas Guignard, Jacques Puechberty, Simon Cabello‐Aguilar, Pascal Pujol, Julie A. Vendrell, Jérôme Solassol   +7 more
openalex   +1 more source

Ir(III) Complexes Convert Cold to Hot Tumors via Ferroptosis/Necroptosis‐Driven Immunogenic Cell Death and Photosensitized CD47 Downregulation

Advanced Science, EarlyView.
Red‐light‐activated Ir1 overcomes hypoxia tolerance and adapts to the immunosuppressive tumor microenvironment, converting immunologically cold tumors into inflamed hot microenvironments. This conversion is driven by synergistic induction of immunogenic cell death through coordinated ferroptosis‐necroptosis pathways and spatiotemporally controlled ...
Long‐Bo Yu, Peng Wang, Qing‐Hua Shen, Qi‐Xin Guan, Zhi‐Yuan Li, Ying‐Ying Han, Xin‐Yi Zhang, Qing‐Yuan Hu, Cai‐Ping Tan   +8 more
wiley   +1 more source

Phase Separation of PHLDB2 Drives EMT and Tumor Progression in Triple-Negative Breast Cancer. [PDF]

Cancer Med
Zhang M, Liang C, Chen T, Shi X, Hao J.
europepmc   +1 more source

Antiemesis Corticosteroids Potentiate Checkpoint Blockade Efficacy by Normalizing the Immune Microenvironment in Metastatic Murine Breast Cancer

Advanced Science, EarlyView.
Corticosteroids improve the efficacy of immune checkpoint blockade therapy in metastatic murine breast cancer. By normalizing the tumor immune microenvironment, corticosteroids reduce immunosuppressive signals, restore T‐cell function, and promote antitumor immune responses, resulting in enhanced tumor control.
John D. Martin, Koji Nagaoka, Myrofora Panagi, Akihiro Hosoi, Fotios Mpkeris, Pengwen Chen, Thahomina T. Khan, Margaret R. Martin, Changbo Sun, Chrysovalantis Voutouri, Maria Louca, Panagiotis Papageorgis, Akira Sumiyoshi, Nobuhiro Nitta, Kazuyoshi Takeda, Ichio Aoki, Kazunori Kataoka, Triantafyllos Stylianopoulos, Kazuhiro Kakimi, Horacio Cabral   +19 more
wiley   +1 more source

Targeting the UFL1-AKT cascade suppresses triple-negative breast cancer progression. [PDF]

Nat Commun
Yang X, Wen Y, Ma X, Qin S, Liu Y, Chen J, Zhang H, Goding CR, Cui R, Liu T.   +9 more
europepmc   +1 more source

A20 Facilitates Oxaliplatin Sensitivity in Colorectal Cancer Through Monoubiquitylation of IKK‐β

Advanced Science, EarlyView.
This study demonstrates that the expression of A20, a ubiquitin‐editing enzyme, is positively correlated with oxaliplatin sensitivity in colorectal cancer (CRC). Mechanistically, A20 enhances oxaliplatin sensitivity by inhibiting NF‐κB nuclear translocation through monoubiquitination of IKK‐β.
Fan Luo, Ting Yang, Jiaxin Cao, Qun Chen, Zhenhai Lu, Feiteng Lu, Chaozhuo Lin, Zengfei Xia, Yuanzhong Yang, Peng Li, Wenjuan Ma, Min Luo, Rongxin Zhang   +12 more
wiley   +1 more source

Prominent protumoral cellular compartments of the tumor microenvironment in triple-negative breast cancer. [PDF]

Front Cell Dev Biol
Sun S, Zhao P, Wang C, Du J, Zhang T, He X, Zuo Z, Li N, Zhou R.   +8 more
europepmc   +1 more source