Results 121 to 130 of about 110,363 (266)

Tubacin plus Erastin Treatment Sensitizes Cell Ferroptosis of Triple Negative Breast Neoplasms

Advances in Clinical Medicine, 2023
openaire   +1 more source

Turning Unpredictable Biomolecule Adsorption to Controlled Corona Formation: Focus on Carbon Nanomaterials

Advanced Materials, EarlyView.
Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou, Yalei Hu, Jie Yu, Naoki Komatsu, Yuta Nishina, Alberto Bianco   +5 more
wiley   +1 more source

Effect of Clinical and Treatment Factors on Survival Outcomes of Triple Negative Breast Cancer Patients

Breast Cancer: Targets and Therapy, 2020
Shelly Wen,1,2 Lucy Manuel,1,2 Moira Doolan,1,2 Justin Westhuyzen,1 Thomas P Shakespeare,1,2 Noel J Aherne1,2 1Department of Radiation Oncology, Mid North Coast Cancer Institute, Coffs Harbour, New South Wales, Australia; 2University of New South Wales ...
Wen S, Manuel L, Doolan M, Westhuyzen J, Shakespeare TP, Aherne NJ   +5 more
doaj  

Unlocking the Potential of MXene‐Based Electrochemical Biosensors: A Review of Biofunctionalization Strategies and Biosensing Principles

Advanced Materials Technologies, EarlyView.
ABSTRACT Electrochemical biosensors enable the accurate and timely detection of clinical biomarkers, improving healthcare and precision medicine. MXene nanosheets, a class of 2D transition metal carbides, nitrides, and carbonitrides, are promising materials for developing next‐generation electrochemical biosensors due to their unique physicochemical ...
Muhsin Ali, Sharat Chandra Barman, Isobel Steer, Aya H. Alshareef, Dana Alsulaiman   +4 more
wiley   +1 more source

Microfluidic Hydroporation Platform for Effective Allogeneic CAR‐T Cell Production and Subsequent Functional Cytotoxicity Analysis

Advanced Materials Technologies, EarlyView.
The hydroporator platform employs controlled hydrodynamic deformation for efficient mRNA and CRISPR/Cas9 delivery into primary human T cells, enabling allogeneic CAR‐T cell manufacturing. It preserves cell functionality and drives potent gene editing, CAR expression, and tumor cytotoxicity, while feature‐based analysis links these functional outcomes ...
Soohyun Jeon, Sein Kim, Hyun‐Young Kim, Duck Cho, Sungsu Park, Seohyun Kim, Aram J. Chung   +6 more
wiley   +1 more source

Metformin sensitizes triple-negative breast cancer to histone deacetylase inhibitors by targeting FGFR4

Journal of Biomedical Science
Background Triple-negative breast cancer (TNBC) is characterized by high malignancy, strong invasiveness, and a propensity for distant metastasis, leading to poor prognosis and relatively limited treatment options.
Zhangyuan Gu, Fugui Ye, Hong Luo, Xiaoguang Li, Yue Gong, Shiqi Mao, Xiaoqing Jia, Xiangchen Han, Boyue Han, Yun Fu, Xiaolin Cheng, Jiejing Li, Zhiming Shao, Peizhen Wen, Xin Hu, Zhigang Zhuang   +15 more
doaj   +1 more source

Real-world survival outcomes of neoadjuvant versus adjuvant chemotherapy in operable triple-negative breast cancer: a propensity score matched registry-based study

Acta Oncologica
Background and purpose: Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype where the prognostic implications of primary systemic therapy followed by surgery, compared to up-front surgery and subsequent adjuvant chemotherapy (ACT),
Ali Inan El-Naggar, Andreas Karakatsanis, Antonios Valachis   +2 more
doaj   +1 more source

Misleading Presentations of Malignant Breast Diseases – Role of Clinical Cytology [PDF]

, 2010
We described two examples with misleading presentations to draw attention to the role of clinical cytology as a part of multidisciplinary approach to breast lesions.
Gordana Kaić, Jovanka Vojnović, Karmen Trutin Ostović, Ljerka Vidović, Radmila Ajduković, Sanda Stanec, Smiljka Lambaša, Srećko Budi, Tajana Štoos-Veić, Višnja Hariš   +9 more
core   +1 more source

Modulus‐Switchable Miniature Robots for Biomedical Applications: A Review

Advanced Robotics Research, EarlyView.
Materials, robot designs, proof‐of‐concept functions, and biomedical applications of modulus‐switchable miniature robots. Miniature soft robots have shown great potential in biomedical applications due to their excellent controllability and suitable mechanical properties in biological environments.
Chunyun Wei, Yibin Wang, Jiangfan Yu
wiley   +1 more source

Integrated Single-Cell and Bulk RNA Sequencing Identifies SERPING1 as a Biomarker of Immune Infiltration and Prognosis in Triple-Negative Breast Cancer

Frontiers in Bioscience-Landmark
Background: Triple-negative breast cancer (TNBC) is an aggressive malignancy that lacks effective treatment. Immune infiltration plays an important role in anti-tumor responses.
Yuhang Shang, Runze Guo, Jiangwei Liu, Weilun Cheng, Anbang Hu, Yansong Liu, Yunqiang Duan, Xuelian Wang, Zhengbo Fang, Yanling Li, Hanyu Zhang, Mingcui Li, Zhiyuan Rong, Yuanhao Ji, Yulin Chen, Delong Cui, Yunyi Ji, Baoliang Guo   +17 more
doaj   +1 more source