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Gene Regulatory Network Analysis for Triple-Negative Breast Neoplasms by Using Gene Expression Data [PDF]

open access: yesJournal of Breast Cancer, 2017
To better identify the physiology of triple-negative breast neoplasm (TNBN), we analyzed the TNBN gene regulatory network using gene expression data.We collected TNBN gene expression data from The Cancer Genome Atlas to construct a TNBN gene regulatory network using least absolute shrinkage and selection operator regression. In addition, we constructed
Jung, Hee Chan   +4 more
openaire   +3 more sources

Comparative proteomic and clinicopathological analysis of breast adenoid cystic carcinoma and basal-like triple-negative breast cancer [PDF]

open access: yesFrontiers in Medicine, 2022
BackgroundAdenoid cystic carcinoma (ACC) is a rare type of triple-negative breast cancer that has an indolent clinical behavior. Given the substantial overlapping morphological, immunohistochemical, and molecular features with other basal-like triple ...
Qian Yao   +8 more
doaj   +2 more sources

A New Gene Expression Signature for Triple-Negative Breast Cancer using Frozen Fresh Tissue before Neoadjuvant chemotherapy

open access: yesMolecular Medicine, 2017
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer tumors. Comparisons between TNBC and non-triple-negative breast cancer (nTNBC) may help to differentiate key components involved in TNBC neoplasms.
Sandra K. Santuario-Facio   +18 more
doaj   +2 more sources

Triple-negative breast cancer histological subtypes with a favourable prognosis [PDF]

open access: yes, 2021
Triple-negative breast cancers (TNBC), as a group of tumours, have a worse prognosis than stage-matched non-TNBC and lack the benefits of routinely available targeted therapy.
European Working Group for Breast Screening Pathology
core   +5 more sources

Mesothelin expression in triple negative breast carcinomas correlates significantly with basal-like phenotype, distant metastases and decreased survival. [PDF]

open access: yesPLoS ONE, 2014
Mesothelin is a cell surface associated antigen expressed on mesothelial cells and in some malignant neoplasms. Mesothelin-targeted therapies are in phase I/II clinical trials. The clinicopathologic and prognostic significance of mesothelin expression in
Gary Tozbikian   +11 more
doaj   +2 more sources

Abscess-like postpartum metaplastic breast carcinoma in breastfeeding woman: a case report

open access: yesBrazilian Journal of Oncology, 2023
Introduction: Breast cancer diagnosed within 10 years of parturition is named postpartum breast cancer which is a highly metastatic tumor with poor prognosis.
Bianca Gardini Ferrari   +5 more
doaj   +1 more source

Insight into the Role of Phytochemicals in the Treatment of Triple-Negative Breast Cancer [PDF]

open access: yesMiddle East Journal of Cancer, 2023
Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer which is characterized by the absence of progesterone receptor, estrogen receptor, and human epidermal growth factor receptor 2, thus, TNBC patient tumour does not ...
Devangkumar Maru, Anmol Kumar
doaj   +1 more source

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