Results 21 to 30 of about 101,408 (263)

Exploring the clinicopathological parameters of HER2 low breast cancers: insights from a retrospective cohort study [PDF]

Korean Journal of Clinical Oncology
Purpose Breast cancer subtypes are delineated by human epidermal growth factor receptor 2 (HER2) expression, pivotal in treatment selection. HER2-positive tumors typically respond to targeted therapies, whereas HER2-negative tumors lack HER2 ...
Sana Ahuja, Adil Aziz Khan, Kiruthikasri G, Sufian Zaheer   +3 more
doaj   +1 more source

GnRH receptor activation competes at a low level with growth signaling in stably transfected human breast cell lines [PDF]

, 2011
Breakthrough Breast CancerBackground: Gonadotrophin releasing hormone (GnRH) analogs lower estrogen levels in pre-menopausal breast cancer patients. GnRH receptor (GnRH-R) activation also directly inhibits the growth of certain cells.
Sims Andrew H, Faratian Dana, Miller, Nicola, Sims, Andrew H., Morgan, Kevin, Miller Nicola, Millar, Robert P., Langdon, Simon P., Ilgin Cagnan, Sims, Andrew, Dana Faratian, Robert P Millar, Meyer, Colette, Simon P Langdon, Colette Meyer, Harrison David J, Cagnan, Ilgin, Nicola Miller, Morgan Kevin, Millar Robert P, David J Harrison, Faratian, Dana, Langdon Simon P, Kevin Morgan, Meyer Colette, Cagnan Ilgin, Andrew H Sims, Harrison, David J.   +27 more
core   +1 more source

High Cytoplasmic CXCR4 Expression Predicts Prolonged Survival in Triple-Negative Breast Cancer Patients Treated with Adjuvant Chemotherapy [PDF]

Journal of Pathology and Translational Medicine, 2018
Background Chemokine receptor CXC chemokine receptor type 4 (CXCR4) and its ligand CXC motif chemokine 12 (CXCL12; stromal cell-derived factor-1) are implicated in tumor growth, metastasis, and tumor cell-microenvironment interaction. A number of studies
Bobae Shim, Min-Sun Jin, Ji Hye Moon, In Ae Park, Han Suk Ryu   +4 more
doaj   +1 more source

Immunotherapy in triple-negative breast cancer: mechanisms of resistance and emerging approaches: a narrative review [PDF]

Journal of Yeungnam Medical Science
Triple-negative breast cancer (TNBC) is characterized by less treatment responsiveness and poorer prognosis than other breast cancer subtypes. The introduction of anti-programmed cell death 1 (PD-1)/programmed cell death ligand 1 (PD-L1) immunotherapy ...
Sung Ae Koh
doaj   +1 more source

Spindle Cell Metaplastic Breast Carcinoma with Leiomyoid Differentiation: A Case Report [PDF]

, 2011
Background: Metaplastic carcinoma of the breast is a rare but distinct entity within the group of undifferentiated invasive carcinomas. This entity accounts for less than 0.5% of all breast cancers and contains elements of epithelial (ductal ...
Jauch, Karl-Walter, Claudius Conrad, Ralf Huss, Nieß, Hanno, Conrad, Claudius, Hanno Nieß, Kaiser, Christina, Christina Kaiser, Karl-Walter Jauch, Huss, Ralf, Diane L. Miller, Miller, Diane L.   +11 more
core   +1 more source

Modern View on the Problem of Triple Negative Breast Cancer

, 2023
Environmental pollution, repeated artificial termination of pregnancy, and improper use of medications create conditions for the development of breast cancer (BC). According to the World Health Organization, “... throughout the world, breast cancer ranks
Atakhanova N. E, Almuradova D. M, Ziyaev Sh. V   +2 more
core   +1 more source

Chitosan nanoparticles containing limonene and limonene-rich essential oils: potential phytotherapy agents for the treatment of melanoma and breast cancers

BMC Complementary Medicine and Therapies, 2021
Background Melanoma and breast cancers are two common cancers worldwide. Due to the side effects of chemotherapy drugs and the occurring resistance against them, the development of green drugs has been received more attention.
Hiva Alipanah, Mojtaba Farjam, Elham Zarenezhad, Ghazaal Roozitalab, Mahmoud Osanloo   +4 more
doaj   +1 more source

Impressive effect of cisplatin monotherapy on a patient with heavily pretreated triple-negative breast cancer with poor performance [PDF]

Yeungnam University Journal of Medicine, 2020
Systemic therapy for metastatic triple-negative breast cancer (TNBC) still remains challenging because there are no targeted agents or endocrine therapies currently available.
Dong Won Baek, Ji-Young Park, Soo Jung Lee, Yee Soo Chae   +3 more
doaj   +1 more source

Real-world data on adjuvant capecitabine after standard neoadjuvant chemotherapy for triple negative breast cancer [PDF]

Revista Brasileira de Ginecologia e Obstetrícia
Objective Neoadjuvant chemotherapy (NACT) has become the standard of care for patients with triple-negative breast cancer (TNBC) with tumors > 1 cm or positive axillary nodes.
Maria Fernanda Imperio Pereira, Isabela Panzeri Carlotti Buzatto, Hélio Humberto Angotti Carrara, Fabiana de Oliveira Buono, Jurandyr Moreira de Andrade, Leonardo Fleury Orlandini, Daniel Guimarães Tiezzi   +6 more
doaj   +1 more source

Salivary gland-type mammary carcinoma arising in microglandular adenosis: A case report and clinicopathological review of the literature

Cancer Treatment and Research Communications, 2020
Introduction: Microglandular adenosis (MGA) is a rare benign proliferative lesion lacking a myoepithelial cell layer; 27% of all reported cases have progressed to invasive carcinoma.
Victoria Rico, Yukiko Shibahara, Marjorie Monteiro, Elzbieta Slodkowska, Samantha Tam, Pearl Zaki, Carlo De Angelis, Edward Chow, Katarzyna Joanna Jerzak   +8 more
doaj   +1 more source