Results 41 to 50 of about 171,342 (310)

Phosphatidylserine-exposing tumor-derived microparticles exacerbate coagulation and cancer cell transendothelial migration in triple-negative breast cancer

Theranostics, 2021
Background: Neoadjuvant chemotherapy is relevant to the formation of thromboembolism and secondary neoplasms in triple-negative breast cancer (TNBC). Chemotherapy-induced breast cancer cell-derived microparticles (BCMPs) may have important thrombogenic ...
Cong Zhang, Zhuowen Yang, P. Zhou, Muxin Yu, Baorong Li, Yingmiao Liu, Jiaqi Jin, Wenhui Liu, Haijiao Jing, Jingwen Du, Jie Tian, Zhiyu Zhao, Jianxin Wang, Yinzhu Chu, Chunmei Zhang, Valerie A. Novakovic, Jialan Shi, Changjun Wu   +17 more
semanticscholar   +1 more source

Real-world data on adjuvant capecitabine after standard neoadjuvant chemotherapy for triple negative breast cancer [PDF]

Revista Brasileira de Ginecologia e Obstetrícia
Objective Neoadjuvant chemotherapy (NACT) has become the standard of care for patients with triple-negative breast cancer (TNBC) with tumors > 1 cm or positive axillary nodes.
Maria Fernanda Imperio Pereira, Isabela Panzeri Carlotti Buzatto, Hélio Humberto Angotti Carrara, Fabiana de Oliveira Buono, Jurandyr Moreira de Andrade, Leonardo Fleury Orlandini, Daniel Guimarães Tiezzi   +6 more
doaj   +1 more source

Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry [PDF]

, 2013
Fixed, paraffin-embedded (FPE) tissues are a potentially rich resource for studying the role of NOTCH1 in cancer and other pathologies, but tests that reliably detect activated NOTCH1 (NICD1) in FPE samples have been lacking.
Ashworth, Todd, Aster, Jon C., Brock, Jane E., Cassidy, Andrew J., Chirieac, Lucian R., Cho, Raymond J., DeAngelo, Daniel J., Dillon, Deborah, Dorfman, David, Haines, Brian B., Hirsch, Michelle, Hornick, Jason L., Kluk, Michael J., Knoechel, Birgit, Krop, Ian E., Lazar, Alexander J. F., Leigh, Irene M., Mason, Emily F., Morgan, Elizabeth A., Oh, David J., Peto, Myron, Pinkus, Geraldine, Pourreyron, Celine, Rodig, Scott, Sathayanrayanan, Sriram, South, Andrew P., Stoeck, Alexander, Wang, Hongfang, Weigert, Oliver, Weinstock, David M.   +29 more
core   +2 more sources

A new immunochemical strategy for triple-negative breast cancer therapy

Scientific Reports, 2021
Triple-negative breast cancer (TNBC) is a highly diverse group of malignant neoplasms which tend to have poor outcomes, and the development of new targets and strategies to treat these cancers is sorely needed.
Chih-Wei Lin, Tianqing Zheng, Geramie Grande, Alex R. Nanna, C. Rader, R. Lerner   +5 more
semanticscholar   +1 more source

Constructing Ontology-Based Cancer Treatment Decision Support System with Case-Based Reasoning [PDF]

, 2018
Decision support is a probabilistic and quantitative method designed for modeling problems in situations with ambiguity. Computer technology can be employed to provide clinical decision support and treatment recommendations.
Colloc, Joël, Guo, Ziyi, Jacquet-Andrieu, Armelle, Liu, Yong, Shen, Ying   +4 more
core   +2 more sources

Triple peptide vaccination as consolidation treatment in women affected by ovarian and breast cancer: clinical and immunological data of a phase I/II clinical trial [PDF]

, 2016
Vaccination with priming and expansion of tumour reacting T cells is an important therapeutic option to be used in combination with novel checkpoint inhibitors to increase the specificity of the T cell infiltrate and the efficacy of the treatment. In
Antonilli M, BARCHIESI, GIACOMO, BELLATI, FILIPPO, BENEDETTI PANICI, PIERLUIGI, CAPONNETTO, SALVATORE, Iadarola R, NAPOLETANO, Chiara, NUTI, Marianna, PIERELLI, LUCA, RAHIMI KOSHKAKI, HASSAN, RUGHETTI, Aurelia, RUSCITO, ILARY, VISCONTI, Valeria, ZIZZARI, ILARIA GRAZIA   +13 more
core   +1 more source

Salivary gland-type mammary carcinoma arising in microglandular adenosis: A case report and clinicopathological review of the literature

Cancer Treatment and Research Communications, 2020
Introduction: Microglandular adenosis (MGA) is a rare benign proliferative lesion lacking a myoepithelial cell layer; 27% of all reported cases have progressed to invasive carcinoma.
Victoria Rico, Yukiko Shibahara, Marjorie Monteiro, Elzbieta Slodkowska, Samantha Tam, Pearl Zaki, Carlo De Angelis, Edward Chow, Katarzyna Joanna Jerzak   +8 more
doaj   +1 more source

Association Between Family History of Malignant Neoplasms and Clinicopathological Features of Breast Cancer Patients

Zhongliu Fangzhi Yanjiu, 2020
Objective To investigate the association between family history of malignant neoplasms (MN-FH) and clinicopathological characteristics of patients with breast cancer.
CAO Xinhua, HAN Lifei, LYU Jianxin, HU Haolin, ZHANG Ya'nan   +4 more
doaj   +1 more source

The neural crest transcription factor SOX 10 is preferentially expressed in triple negative breast carcinomas.

Interamerican Journal of Health Sciences, 2021
Introduction: The expression of SOX 10 by immunohistochemistry has been documented in benign breast myoepithelial cells and in ductal carcinomas classified by the molecular subtype defined by immunohistochemistry.
A. Arra, Daniel Coso, Rosana Ramos Dos Santos   +2 more
semanticscholar   +1 more source

Current Issues and Clinical Evidence in Tumor-Infiltrating Lymphocytes in Breast Cancer [PDF]

Journal of Pathology and Translational Medicine, 2015
With the advance in personalized therapeutic strategies in patients with breast cancer, there is an increasing need for biomarker-guided therapy. Although the immunogenicity of breast cancer has not been strongly considered in research or practice, tumor-
Sung Gwe Ahn, Joon Jeong, SoonWon Hong, Woo Hee Jung   +3 more
doaj   +1 more source