Results 61 to 70 of about 171,342 (310)

ABC4 Consensus: First Latin American Meeting—Assessment, Comments, and Application of Its Recommendations

JCO Global Oncology, 2020
Breast cancer accounts for a high burden among all the neoplasms in Latin America, with more-advanced stages at presentation, which could result in high mortality rates.
Henry L. Gomez, Carlos Castañeda, Fernando Valencia, Rene Muñoz-Bermeo, Maria del Carmen Torrico, Silvia Neciosup   +5 more
doaj   +1 more source

The interaction ‘Supply’, ‘Demand’, and ‘Technological Capabilities’ in terms of Medical Subject Headings: A triple helix model of medical innovations [PDF]

, 2015
We develop a model of innovation that enables us to trace the interplay among three key dimensions of the innovation process: (i) demand of and (ii) supply for innovation, and (iii) technological capabilities available to generate innovation in the forms
Leydesdorff, L., Petersen, Alexander M., Rotolo, D.   +2 more
core   +1 more source

Different activity and toxicity of immunotherapy in monozygotic twins diagnosed with early triple-negative breast cancer: a case report

Therapeutic Advances in Medical Oncology
Breast cancer (BC) is the most common malignancy among women. Among 5%–10% of diagnoses are correlated with hereditary cancer syndromes, while the remaining cases are sporadic and linked to multiple factors.
M. Perachino, L. Del Mastro, Giulia Buzzatti, Lucia Trevisan, M. Razeti, Andrea Bellodi, S. Spinaci, Davide Soldato, M. Lambertini, Francesca Poggio   +9 more
semanticscholar   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Cardiac transplantation and neoplasms: experiences at Escola Paulista de Medicina of the Federal University of São Paulo [PDF]

, 2006
OBJECTIVE: To study the occurrence and types of neoplasms developed by patients who underwent an orthotopic cardiac transplantation under the Program of Cardiac Transplantation of Escola Paulista de Medicina, Federal University of São Paulo.
Aguiar, Luciano de Figueiredo, Branco, João Nelson Rodrigues, Buffolo, Enio, Catani, Roberto, Mello Junior, Walter Teixeira de, Paez, Rodrigo Pereira   +5 more
core   +5 more sources

Huaier-induced suppression of cancer-associated fibroblasts confers immunotherapeutic sensitivity in triple-negative breast cancer.

Phytomedicine
BACKGROUND Triple-negative breast cancer (TNBC) is the most intractable subgroup of breast neoplasms due to its aggressive nature. In recent years, immune checkpoint inhibitors (ICIs) have exhibited potential efficacy in TNBC treatment.
Chen Li, Xiaolong Wang, Luyao Xing, Tong Chen, Wenhao Li, Xin Li, Yifei Wang, Chao Yang, Qifeng Yang   +8 more
semanticscholar   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Apatinib plus etoposide in pretreated patients with advanced triple-negative breast cancer: a phase II trial

BMC Cancer, 2023
Background Treatment options for pretreated triple-negative breast cancer (TNBC) are limited. This study aimed to evaluate the efficacy and safety of apatinib, an antiangiogenic agent, in combination of etoposide for pretreated patients with advanced ...
Mengru Cao, Hailing Lu, Shi Yan, Hui Pang, Lichun Sun, Chunhong Li, Xuesong Chen, Wei Liu, Jing Hu, Jian Huang, Ying Xing, Ningzhi Zhang, Yingqi Chen, Ting He, Danni Zhao, Yuanyuan Sun, Lin Zhao, Xiaomeng Liu, Li Cai   +18 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Use of positron emission tomography-computed tomography to predict axillary metastasis in patients with triple-negative breast cancer [PDF]

Korean Journal of Clinical Oncology, 2018
Purpose Axillary lymph node dissection (ALND) and sentinel lymph node biopsy (SLNB) are important for staging of patients with node-positive breast cancer.
Jung Hyun Youm, Yoona Chung, You Jung Yang, Sang Ah Han, Jeong Yoon Song   +4 more
doaj   +1 more source