Results 11 to 20 of about 164,343 (265)

An exploratory study for tuft cells in the breast and their relevance in triple-negative breast cancer: the possible relationship of SOX9

BMC Cancer, 2023
Background Breast cancer is highly heterogeneous, suggesting that small but relevant subsets have been under-recognized. Rare and mainly triple-negative breast cancers (TNBCs) were recently found to exhibit tuft cell-like expression profiles, including ...
Yosuke Yamada, Ronald Simon, Kosuke Iwane, Yuki Nakanishi, Yasuhide Takeuchi, Akihiko Yoshizawa, Masahiro Takada, Masakazu Toi, Hironori Haga, Alexander Marx, Guido Sauter   +10 more
doaj   +1 more source

Secretory breast carcinoma in adulthood: A case report with literature review [PDF]

Vojnosanitetski Pregled, 2020
Introduction. Secretory breast carcinoma is rare subtype of breast carcinoma which occurs primarily in children and young adults, so in the past it was called juvenile carcinoma. Case report.
Ivković-Kapicl Tatjana, Vicko Ferenc, Popović Lazar, Đilas Dragana, Lakić Tanja   +4 more
doaj   +1 more source

Highly proliferative and hypodifferentiated CAR-T cells targeting B7-H3 enhance antitumor activity against ovarian and triple-negative breast cancers.

Cancer Letters, 2023
Chimeric antigen receptor (CAR)-T cell immunotherapy is highly effective against hematological neoplasms. However, owing to tumor variability, low antigen specificity, and impermanent viability of CAR-T cells, their use in the treatment of solid tumors ...
Xiaoshuai Zhang, Haiyan Guo, Jie Chen, Chenxiao Xu, Lei Wang, Yong Ke, Yang Gao, Baohong Zhang, Jianwei Zhu   +8 more
semanticscholar   +1 more source

Prognostic Significance of Trophoblastic Cell Surface Protein 2 (Trop2) Expression in Breast Cancer and Relation to Microvascular Density [PDF]

Egyptian Journal of Cancer and Biomedical Research, 2021
Background: The expression of trophoblastic cell surface protein 2 (Trop2) has been correlated with aggressive behavior in multiple malignant neoplasms. Moreover, it is a promising therapeutic target for several malignancies.
Alaa Amer, Sara Darwish, Fatma Ibrahim
doaj   +1 more source

Triple Negative Breast Cancer Preclinical Therapeutic Management by a Cationic Ruthenium-Based Nucleolipid Nanosystem

International Journal of Molecular Sciences, 2023
Based on compelling preclinical evidence concerning the progress of our novel ruthenium-based metallotherapeutics, we are focusing research efforts on challenging indications for the treatment of invasive neoplasms such as the triple-negative breast ...
M. Ferraro, Marco Bocchetti, Claudia Riccardi, M. Trifuoggi, L. Paduano, D. Montesarchio, Gabriella Misso, Rita Santamaria, Marialuisa Piccolo, Carlo Irace   +9 more
semanticscholar   +1 more source

PRR15 deficiency facilitates malignant progression by mediating PI3K/Akt signaling and predicts clinical prognosis in triple-negative rather than non-triple-negative breast cancer

Cell Death and Disease, 2023
Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast neoplasms with a higher risk of recurrence and metastasis than non-TNBC. Nevertheless, the factors responsible for the differences in the malignant behavior between TNBC and ...
Fengzhu Guo, Jialu Ma, Cong Li, Shuning Liu, Weizheng Wu, Chun-xiao Li, Jiani Wang, Jin-song Wang, Zhijun Li, J. Zhai, F. Sun, Yan-tong Zhou, Changyuan Guo, H. Qian, Bing-he Xu   +14 more
semanticscholar   +1 more source

Defining triple‐negative breast cancer with neuroendocrine differentiation (TNBC‐NED)

The Journal of Pathology: Clinical Research, 2023
Primary breast neuroendocrine (NE) neoplasms are uncommon, and definitions harbor controversy. We retrospectively collected 73 triple‐negative breast cancers (TNBC) and evaluated NE biomarker expression along with p53 aberrant staining (which correlates ...
Sean M. Hacking, E. Yakirevich, Yihong Wang   +2 more
semanticscholar   +1 more source

Synchronous Occurrence of Triple-Negative Breast Cancer and Malignant Melanoma

Journal of Medical Cases, 2023
In people with cancer, multiple primary malignant neoplasms (MPMNs) are not unusual, and they may be caused by risk factors such as genetics, viral infection, smoking, environmental factors, or treatment-related variables.
M. Taushanova, Y. Milusheva, D. Manov, Ralitza Rosen Hadjieva, A. Yordanov   +4 more
semanticscholar   +1 more source

Sonography with vertical orientation feature predicts worse disease outcome in triple negative breast cancer

Breast, 2020
Objectives: Triple negative breast cancer (TNBC) is a heterogenous disease and associated with unfavorable outcomes. The role of sonographic features and its association with disease outcome in TNBC is uncertain.
Haoyu Wang, Weiwei Zhan, Weiguo Chen, Yafen Li, Xiaosong Chen, Kunwei Shen   +5 more
doaj   +1 more source

Modern View on the Problem of Triple Negative Breast Cancer

Texas Journal of Medical Science, 2023
Environmental pollution, repeated artificial termination of pregnancy, and improper use of medications create conditions for the development of breast cancer (BC). According to the World Health Organization, “... throughout the world, breast cancer ranks
Z. Sh, Tashkent Medical Academy, Uzbekistan   +2 more
semanticscholar   +1 more source