BMC Cancer, 2023 Background Breast cancer is highly heterogeneous, suggesting that small but relevant subsets have been under-recognized. Rare and mainly triple-negative breast cancers (TNBCs) were recently found to exhibit tuft cell-like expression profiles, including ...
Yosuke Yamada +10 more
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Breast, 2020 Objectives: Triple negative breast cancer (TNBC) is a heterogenous disease and associated with unfavorable outcomes. The role of sonographic features and its association with disease outcome in TNBC is uncertain.
Haoyu Wang +5 more
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The molecular landscape of breast mucoepidermoid carcinoma
Cancer Medicine, 2023 Mucoepidermoid carcinoma (MEC) of the breast is an extremely rare salivary gland‐type tumor characterized by epidermoid, basaloid, intermediate, and/or mucinous cells arranged in solid and cystic patterns.
Konstantinos Venetis +15 more
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Exploring the clinicopathological parameters of HER2 low breast cancers: insights from a retrospective cohort study [PDF]
Korean Journal of Clinical OncologyPurpose Breast cancer subtypes are delineated by human epidermal growth factor receptor 2 (HER2) expression, pivotal in treatment selection. HER2-positive tumors typically respond to targeted therapies, whereas HER2-negative tumors lack HER2 ...
Sana Ahuja +3 more
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High Cytoplasmic CXCR4 Expression Predicts Prolonged Survival in Triple-Negative Breast Cancer Patients Treated with Adjuvant Chemotherapy [PDF]
Journal of Pathology and Translational Medicine, 2018 Background Chemokine receptor CXC chemokine receptor type 4 (CXCR4) and its ligand CXC motif chemokine 12 (CXCL12; stromal cell-derived factor-1) are implicated in tumor growth, metastasis, and tumor cell-microenvironment interaction. A number of studies
Bobae Shim +4 more
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A novel combination of triple metachronous malignancies of the kidney, oropharynx and prostate. A case report [PDF]
, 2015 Synchronous or metachronous malignancies are a rare event, with an incidence rate that increases with age. The present study reports the case of a 70-year-old Caucasian male who was referred to the outpatient office of the Urology Unit, Sapienza ...
Carbone, Antonio +6 more
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Impressive effect of cisplatin monotherapy on a patient with heavily pretreated triple-negative breast cancer with poor performance [PDF]
Yeungnam University Journal of Medicine, 2020 Systemic therapy for metastatic triple-negative breast cancer (TNBC) still remains challenging because there are no targeted agents or endocrine therapies currently available.
Dong Won Baek +3 more
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TTF-1/p63-positive poorly differentiated NSCLC: A histogenetic hypothesis from the basal reserve cell of the terminal respiratory unit [PDF]
, 2020 TTF-1 is expressed in the alveolar epithelium and in the basal cells of distal terminal bronchioles. It is considered the most sensitive and specific marker to define the adenocarcinoma arising from the terminal respiratory unit (TRU). TTF-1, CK7, CK5/6,
Barraco N. +8 more
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Immunotherapy in triple-negative breast cancer: mechanisms of resistance and emerging approaches: a narrative review [PDF]
Journal of Yeungnam Medical ScienceTriple-negative breast cancer (TNBC) is characterized by less treatment responsiveness and poorer prognosis than other breast cancer subtypes. The introduction of anti-programmed cell death 1 (PD-1)/programmed cell death ligand 1 (PD-L1) immunotherapy ...
Sung Ae Koh
doaj +1 more source
Neoadjuvant therapy for breast cancer [PDF]
, 2019 Objective: To evaluate the frequency of neoadjuvant therapy (NT) in women with stage I–III breast cancer in Italy and whether it is influenced by biological characteristics, screening history, and geographic area.
Carrozzi G. +10 more
core +1 more source