Results 41 to 50 of about 6,834 (166)
Research on the Mechanism of Natural Products Acting on Chronic Obstructive Pulmonary Disease
This figure illustrates that approximately 80 natural compounds exert therapeutic effects against chronic obstructive pulmonary disease by targeting pathological mechanisms such as airway inflammation, oxidative stress, airway remodeling, mucus hypersecretion, emphysema, protease–antiprotease imbalance, apoptosis, and autophagy.
Shuna Wei, Xiaoju Liu
wiley +1 more source
Triterpene glycosides isolated from holothurians are natural products known to possess cytotoxic properties against cancer cells. However, their anticancer prophylactic activity has not been studied sufficiently.
Sergey N. Fedorov +8 more
doaj +1 more source
This study selected three fruit types of LT, including PCS, ES, and LFS. We examined the phenotypes and physicochemical components, volatile substances, non‐volatile substances, and FT‐NIRS characteristics of the three fruit types. Based on FT‐NIRS, an SVM model was established for the rapid identification of LT fruit types.
Dengke Fu +6 more
wiley +1 more source
Clarification of the Saponin Composition of Tubers
Six known saponins, glycosides of hederagenin and oleanolic acid, have been isolated from the tubers of Ranunculus ficaria L. (Ranunculaceae). Their separation included the use of centrifugal partition chromatography (CPC).
Andrew Marston +5 more
doaj +1 more source
Dietary polyphenols and phytochemicals suppress NF‐κB signaling. Mechanistically, by inhibiting IκBα degradation and preventing nuclear translocation of p65/p50 complexes, the polyphenols reduce the expression of pro‐inflammatory and pro‐survival genes, thereby decreasing overall cancer cell survival.
Khuzin Dinislam +3 more
wiley +1 more source
Eleutherococcus senticosus is a valuable medicinal plant, and the biosynthesis of its key secondary metabolites, triterpene glycosides, is regulated by both DNA methylation and environmental factors.
Xueying Zhao +6 more
doaj +1 more source
New minor triterpene glycoside, cucumarioside E (1) has been isolated from the Far Eastern sea cucumber Cucumaria japonica . The structure of the glycoside was elucidated by 2D-NMR specroscopy and mass-spectrometry.
Alexandra S. Silchenko +7 more
doaj +1 more source
Natural Products as Modulators of ABC Transporters in Breast Cancer
ABSTRACT Breast cancer remains a significant global health challenge, with high incidence and mortality rates despite advancements in early detection and treatment. Multidrug resistance (MDR), particularly in aggressive subtypes like triple‐negative breast cancer (TNBC), continues to hinder effective therapy.
Yoganishalini Sagadevan +2 more
wiley +1 more source
Triterpene saponins of Trigonella monspeliaca L.
The triterpene saponin fraction was isolated from Trigonella monspeliaca tops. It consisted of ten saponosides, three of which were determined to be medicagenic acid glycosides, the other seven - soyasapogenol glucosides.
Wiesław Oleszek +3 more
doaj +1 more source
The preparation for Tunisian pomegranate anthocyanin extract. The molecular mechanisms underlying the antioxidant effects of these compounds were investigated using network pharmacology and molecular docking. Antioxidant activity was evaluated through DPPH, ABTS, and FRAP assays, whereas the effects on oxidative stress and inflammation were examined in
Jing Zhang +6 more
wiley +1 more source

