Results 101 to 110 of about 88,531 (294)

Influence of Selected Abiotic Factors on Triterpenoid Biosynthesis and Saponin Secretion in Marigold (Calendula officinalis L.) in Vitro Hairy Root Cultures

Molecules, 2019
The aim of the study was the evaluation of the efficiency of selected abiotic elicitors, i.e., silver and cadmium ions, ultrasound, and UV-C irradiation, in the stimulation of triterpenoid biosynthesis, accumulation, and saponin secretion in Calendula ...
A. Alsoufi, C. Pączkowski, Marek Długosz, A. Szakiel   +3 more
semanticscholar   +1 more source

Fecal Steroids as Tracers of Human Population and Waste Management Practices at the Ancient Maya City of Ucanal, Guatemala

Archaeometry, EarlyView.
ABSTRACT Geochemical data compiled from dried sediments from three water reservoirs at the ancient Maya city of Ucanal, Petén, Guatemala, reveal low to undetectable fecal biomarker concentrations. These low concentrations may be the result of the aerobic decay of sterols combined with well‐managed waste disposal practices.
Jean D. Tremblay, Peter M. J. Douglas, Christina T. Halperin, Yves Gélinas   +3 more
wiley   +1 more source

Transaminase Enzyme and Liver Histological Profile of Mice Administered Extract of Pegagan (Centella Asiatica (L.) Urban) [PDF]

, 2011
The purpose of this study was to determine whether pegagan caused toxic effects on the liver. This study used completely randomized design with four treatments, ie 125, 200, 275 mg/kg BW and control, each treatment consisting of six replicates. Variables
Adi, T. T. (T), Kiptiyah, K. (Kiptiyah), Muchtaromah, B. (B)   +2 more
core  

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Triterpenoid Saponins from Anemone flaccida Suppress Tumor Cell Proliferation by Regulating MAPK, PD1/PDL1, and STAT3 Signaling Pathways and Altering Cancer Metabolism

OncoTargets and Therapy, 2019
Purpose Natural triterpenoid saponins isolated from Anemone flaccida Fr. Schmidt have exhibited anti-cancer properties and exerted remarkable inhibitory effects on tumor growth.
Lintao Han, Shiqi Yao, Sa Cao, Guo-yan Mo, Jingjing Li, Yan Cao, Fang Huang   +6 more
semanticscholar   +1 more source

Cleaning of water-gilded surfaces using hydro- and solvent-gels [PDF]

, 2013
This paper describes the implementation of three customized gels on a 19th century panel painting for the removal of its degraded natural resin varnish from a water-gilded surface and a complex solvent-sensitive stratigraphic construction over the gilded
Bakalarou, Angeliki, Theodorakopoulos, Charis   +1 more
core  

Metabolomic and Single‐Cell Transcriptomic Analyses Shed Light on Secondary Metabolite Profiling and Potential Developmental Dynamics of Glandular Trichomes in Artemisia argyi

Plant Biotechnology Journal, EarlyView.
ABSTRACT Plant glandular trichomes (GTs) are characterised by their ability to synthesise and store abundant secondary metabolites of significant biological importance. The medicinal plant Artemisia argyi exhibits a dense covering of GTs, yet the precise metabolic compositions and the developmental molecular dynamics of A.
Shuting Dong, Hongyu Chen, Sijie Sun, Miaoxian Guo, Chao Sun, Shilin Chen, Hongmei Luo   +6 more
wiley   +1 more source

Loss‐of‐Function Mutation in CER2‐LIKE1 Reduced Accumulation of Cuticular Wax and Susceptibility to Thrips in Welsh Onion

Plant Biotechnology Journal, EarlyView.
ABSTRACT Cuticular waxes can form a hydrophobic barrier on aerial plant surfaces, which is essential for mediating plant‐environment interactions by providing protection against both biotic and abiotic stresses. In this study, a cuticular wax mutant (gl) was identified and characterised in Welsh onion (Allium fistulosum L.), exhibiting a functional ...
Jiayi Xing, Huanhuan Xu, Mifeng Bai, Yundan Cong, Huiying Liu, Yongqin Wang   +5 more
wiley   +1 more source

Dammarane-Type 3,4-seco-Triterpenoid from Silver Birch (Betula pendula Roth) Buds Induces Melanoma Cell Death by Promotion of Apoptosis and Autophagy

Molecules
Despite unquestionable advances in therapy, melanoma is still characterized by a high mortality rate. For years, high expectations have been raised by compounds of natural origin as a component of pharmacotherapy, particularly by triterpenes found in the
Lukasz Szoka, Marcin Stocki, Valery Isidorov   +2 more
doaj   +1 more source

Mitochondria-Targeted Lupane Triterpenoid Derivatives and Their Selective Apoptosis-Inducing Anticancer Mechanisms.

Journal of Medicinal Chemistry, 2017
Betulin and betulinic acid have been widely studied for their anticancer activities. However, their further development is limited due to low bioavailability, poor aqueous solubility, and limited intracellular accumulation.
Yaqing Ye, Zhang Tao, Huiqing Yuan, Defeng Li, H. Lou, Peihong Fan   +5 more
semanticscholar   +1 more source