Results 101 to 110 of about 33,063 (219)

In Vitro Antidiabetic Evaluation and Phytochemical Characterization of Sapindus mukorossi Fruit Pericarp Extract

Applied Research, Volume 5, Issue 4, August 2026.
Sapindus mukorossi fruit pericarp is a promising source of polar polyphenols and amphiphilic saponins, with the 70% ethanol extract showing the richest phytochemical profile and strongest α‐amylase inhibition. Its solvent‐dependent bioactive composition suggests potential application in managing postprandial hyperglycemia by modulating dietary starch ...
Keisham Subharani Devi, Leishangthem Jetlee Singh, Kongbrailatpam Gayatri Sharma, Thokchom Prasanta Singh   +3 more
wiley   +1 more source

Discovery of VEGFR‐2 Inhibitors From Leonurus japonicus via Integrated Genetic Authentication, Molecular Networking, and In Silico Analysis

Archiv der Pharmazie, Volume 359, Issue 8, August 2026.
Genetic authentication of Leonurus japonicus was confirmed using ITS sequencing. UHPLC‐MS/MS‐GNPS analysis and isolation led to a new labdane diterpenoid (1) and known compounds (2–6), with anti‐angiogenic activity validated by EPC assays and VEGFR‐2 docking studies.
Thiyagarajan Raviraj, Chen‐Lin Yu, Aekkhaluck Intharuksa, Shang‐Chih Lai, Vidya Febrasca Tenderly, Yen Chi Loo, Pin‐Wei Chen, Shih‐Wei Wang, Kartiko Arif Purnomo, Soundar Rajan Kulandhaivel, Sedin Renadi, Stephen Lirio, Yuan‐Bin Cheng, Yu‐Liang Yang, Tsong‐Long Hwang, Fang‐Rong Chang, Michal Korinek   +16 more
wiley   +1 more source

Lippia umbellata Cav.: Chemical Composition, Insecticidal, and Antimicrobial Activities

Chemistry &Biodiversity, Volume 23, Issue 8, August 2026.
Hexane extracts of Lippia umbellata leaves and flowers contain lupenone, α‐amyrin, and hentriacontane. They exhibit insecticidal activity against Drosophila melanogaster and inhibit AChE in vitro and in silico. Furthermore, the extracts can inhibit the growth of medically important bacteria and yeasts, including multidrug‐resistant strains.
José Guillermo Avila‐Acevedo, Miriam Arlette López‐Pérez, Ana Karen Villagómez‐Guzmán, Edgar Antonio Estrella‐Parra, Nallely Álvarez‐Santos, Israel Valencia‐Quiroz, Julieta Orozco‐Martínez, Ma. Edith López‐Villafranco, Silvia Aguilar‐Rodríguez, Carlos Leonardo Céspedes‐Acuña, Juio Alarcón‐Enos, Ana María García‐Bores   +11 more
wiley   +1 more source

Dietary Terpenoids in Advancing Biofilm‐Mediated Cancer Prevention: Antibiofilm Cascade, Molecular Crosstalk, and Nano‐Facilitated Functional Delivery

Cell Biochemistry and Function, Volume 44, Issue 8, August 2026.
ABSTRACT The role of microbes in cancer is gaining attention these days, especially in the context of tumor‐associated biofilms and dysbiotic microbiota. Biofilm‐producing microorganisms, such as Fusobacterium nucleatum and Helicobacter pylori, trigger oncogenic inflammation and immune evasion in tumor initiation and progression, and in the development
Saikat Mazumder, Aditi Dey, Debasmita Bhattacharya, Dibyajit Lahiri, Moupriya Nag, Sudhriti Maity, Navin Kumar, Soumya Pandit, Vaseem Raja, Shubham Sharma, Shashi Prakash Dwivedi, Mithul Rajeev, Juwita Ratna Dewi, Lola Sanayeva, Dilbar Azimova   +14 more
wiley   +1 more source

Stage‐Specific Metabolic and Proteomic Dynamics Underlying Ripening and Quality Formation in Tropical Evergreen Pomegranate

eFood, Volume 7, Issue 4, August 2026.
Integrated multi‐omics reveals that pomegranate ripening between 90 and 130 days drives optimal sugar‐acid balance and pigmentation via coordinated regulation of phenylpropanoid, flavonoid, and carbohydrate metabolism pathways. ABSTRACT Pomegranate fruit development involves coordinated physiological, metabolic, and proteomic changes shaping coloration
Yawen Zhang, Ling Wei, Kaibing Zhou, Qin Deng, Muhammad Mobeen Tahir, Hongxia Wu, Minjie Qian   +6 more
wiley   +1 more source

Integrated Metabolomic and Transcriptomic Analysis Revealed the Capsanthin Biosynthesis and Sequestration in Processing Type Red Pepper (Capsicum annuum var. conoides)

eFood, Volume 7, Issue 4, August 2026.
This study establishes that fruit color divergence in Yanjiao pepper cultivars arises from hierarchical regulation of carotenoid metabolism, driven by yellow‐blue chromaticity variation and cultivar‐specific metabolic strategies. These findings provide a mechanistic framework for breeding peppers with enhanced color stability and nutraceutical value ...
Qi Chen, Ming Wang, Minjie Duan, Youjin Hao, Jian Ming, Honghai Li   +5 more
wiley   +1 more source

Integrated Evaluation of the Multifunctional Bioactivity of Curcuma zedoaria (Christm.) Roscoe Essential Oil: Antimicrobial, Insecticidal, and Postharvest Effects on Fresh Ginger

eFood, Volume 7, Issue 4, August 2026.
Multifunctional bioactivity of Curcuma zedoaria essential oil. ABSTRACT Plant‐derived essential oils are increasingly investigated as sustainable alternatives for food preservation and crop protection; however, their multifunctional applicability under postharvest conditions remains insufficiently explored.
Miroslava Kačániová, Minhang Qiao, Joel Horacio Elizondo‐Luevano, Zhaojun Ban, Li Li, Yizhou Gao, Anis Ben Hsouna, Rania Ben Saad, Maciej Ireneusz Kluz, Stefania Garzoli   +9 more
wiley   +1 more source

Physapubescin B From Physalis: A Food‐Derived Withanolide for Cancer Chemoprevention and Nutraceutical Development

eFood, Volume 7, Issue 4, August 2026.
Physapubescin B may interfere with multiple cancer‐associated signaling pathways by inhibiting Ras/Raf/mitogen‐activated protein kinase kinase/extracellular signal‐regulated kinase (Ras/Raf/MEK/ERK) signaling and vascular endothelial growth factor (VEGF)‐dependent angiogenesis.
Wojciech Koch, Katarzyna Stępnik, Anna Wawruszak, Estera Okoń, Agata Jarząb, Katarzyna Gaweł‐Bęben, Magdalena Michalak‐Tomczyk, Jacek Jachuła, Magdalena Zdziebło, Paweł Helon, Javad Sharifi‐Rad, Daniela Calina   +11 more
wiley   +1 more source

Investigating the Antidiabetic Effects of Calotropis procera: Preclinical Assessment

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Calotropis Procera In vitro/Diabetic rodent model Improved β‐cell function, reduced hepatic gluconeogenesis antioxidant activity. ABSTRACT Diabetes mellitus (DM) is a metabolic disease characterized by persistent hyperglycemia, oxidative stress, and inflammation, often leading to severe complications.
Yu‐Cheng Kuo, Musa I. Ajibola, Halimat Y. Lukman, Bashir Lawal, Lung‐Ching Chen, Sheng‐Liang Huang, Olawale David Ajayi, Sunday Amos Onikanni, Saheed Sabiu, Leandro Miranda‐Alves, Hsu‐Shan Huang   +10 more
wiley   +1 more source

Regulatory Mechanisms of Salinity-Induced Triterpenoid Saponin Biosynthesis in <i>Cyclocarya paliurus</i> Seedling Revealed by Integrated Multi-Omics Analysis and Molecular Docking. [PDF]

Plants (Basel)
Hong K, Chen H, Qin J, Fang S, Shang X, Zhang L.   +5 more
europepmc   +1 more source