Results 151 to 160 of about 88,531 (294)

Metabolite Profiling and Anticancer Evaluation of Iraqi Haloxylon articulatum Halophyte via LC–HRMS/MS, Molecular Docking, and ADMET Analysis

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
This study investigates the phytochemical composition and biological activities of a hydroalcoholic extract of Haloxylon articulatum. LC‐HRMS/MS identified diverse bioactive compounds, notably N‐caffeoyltyramine and sinapoyltyramine. The extract exhibited strong antioxidant activity and significant cytotoxic effects against gastric cancer cell lines ...
Jihen Abidi, Amal Ben Hassena, Rania Ben Hmida, Łukasz Kulinowski, Erdi Can Aytar, Reyedh R. Al‐Rashidi, Mohamed Bouaziz   +6 more
wiley   +1 more source

Aktivitas Antioksidan Dan Antibakteri Ekstrak Jeroan Teripang Holothuria Atra Dari Perairan Pulau Biawak Kabupaten Indramayu [PDF]

, 2015
Penelitian ini dilakukan untuk mengetahui kandungan metabolit sekunder pada jeroan teripang Holothuria atra dan potensinya sebagai antioksidan dan antibakteri. Penelitian ini dilaksanakan pada bulan November 2014 s/d Mei 2015 di Laboratorium Bioteknologi
Mulyani, Y. (Yeni), Oktaviani, D. (Dewi), Rochima, E. (Emma)   +2 more
core   +1 more source

Action of Betulinic Acid in the Inhibition of Efflux Pump NorA in Staphylococcus aureus Strains: In Vitro and In Silico Approaches

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
ABSTRACT Antibiotic resistance poses a serious challenge to public health, particularly in the case of Staphylococcus aureus, a Gram‐positive bacterium that employs multiple resistance mechanisms, including efflux pumps such as NorA, which extrude antimicrobial compounds from the cell and reduce antibiotic efficacy. Therefore, the search for substances
Camila Aparecida Pereira da Silva, Nara juliana Santos Araujo, Cícera Datiane Morais Oliveira‐Tintino, José Maria Barbosa Filho, Gabriel Gonçalves Alencar, José Bezerra de Araújo‐Neto, Josefa Sayonara dos Santos, Juliete Bezerra Soares, Carolina Bandeira Domiciano, Henrique Douglas Melo Coutinho, Jacqueline Cosmo Andrade‐Pinheiro   +10 more
wiley   +1 more source

Respon Tanaman Pegagan (Centella Asiatica L. Urban) terhadap Pemberian Pupuk Alami di Bawah Naungan [PDF]

, 2007
The objectives of this experiment was to study the growth, yield and qualitative bioactive compounds of Indian pennyworth (Centella asiatica L. Urban) under different shading levels and biofertilizers.
Aziz, S. A. (Sandra), Kartosoewarno, S. (Suyanto), Musyarofah, N. (Neni), Susanto, S. (Slamet)   +3 more
core  

Chemical and Biological Properties of Hymenaea courbaril L.: A Review

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
PRISMA‐style flowchart showing the screening process of studies identified and selected in the review has been added to the attachments. ABSTRACT Hymenaea courbaril L., commonly known as jatobá, is a plant traditionally used by native populations for medicinal purposes, in addition to providing edible fruits and durable wood for construction.
Cicera Alane Coelho Gonçalves, Geane Gabriele de Oliveira Souza, Ana Maria Fernandes Duarte, Joice Barbosa do Nascimento, Fázia Fernandes Galvão Rodrigues, José Galberto Martins da Costa, Fabíola Fernandes Galvão Rodrigues   +6 more
wiley   +1 more source

Aktivitas Antijamur Senyawa Bioaktif Ekstrak Gelidium Latifolium Terhadap Candida Albicans [PDF]

, 2012
Gelidium sp. has bioactive compounds which is estimated has potential activity as antifungal. The aim of this study were to know bioactive compounds from Gelidium latifolium with different solvent, to know the potency of Gelidium latifolium extract as ...
Dewi, E. N. (Eko), Lutfiyanti, R. (Rosiska), Ma'ruf, W. F. (Widodo)   +2 more
core  

Targeting Staphylococcus aureus Biofilms Through Aurisin Derivatives From Neonothopanus nambi of African Origin

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
This study describes the isolation and characterization of potent bioactive compounds from the fungal strain Neonothopanus nambi, followed by structural elucidation. The compounds shown are dimeric aristolane‐type sesquiterpenoids, identified as aurisins D (1) and B (2).
Syeda J. Khalid, Njogu M. Kimani, Yuanyuyue Huang, Mathias Müsken, Jan‐Peer Wennrich, Jonas Bentrup, Miroslav Kolařík, Josphat Clemet Matasyoh, Hedda Schrey   +8 more
wiley   +1 more source

Characterization, Antimicrobial, and Antiproliferative Activities of Silver Nanoparticles Biosynthesized Using Terminalia phanerophlebia Engl. & Diels

Cell Biochemistry and Function, Volume 44, Issue 2, February 2026.
ABSTRACT The application of nanoparticles (NPs) as therapeutic strategies for treating microbial infections and cancer is gaining attention due to their physicochemical properties. In this study, we synthesized silver nanoparticles (AgNPs) from the aqueous extract of the roots and leaves of Terminalia phanerophlebia.
Folasade O. Banji‐Onisile, Nneka A. Akwu, Tosin A. Olasehinde, Ademola O. Olaniran   +3 more
wiley   +1 more source

Pachymic Acid Targets PI3K/Akt Signaling Pathway to Attenuate tPA‐Induced Hemorrhagic Transformation After Ischemic Stroke

CNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.
Pachymic acid protects blood–brain barrier (BBB) integrity by decreasing the degradation of tight junction proteins caused by tissue plasminogen activator (tPA). Pachymic acid activates the PI3K/Akt pathway via direct binding to PI3K protein, mitigating BBB damage and hemorrhagic transformation induced by tPA after ischemic stroke.
Yongshi Wu, Tong Zhang, Ruoqi Li, Yige Wu, Congmin Wei, Fangming Sun, Shanshan Zhang, Xiang Fan   +7 more
wiley   +1 more source

Cycloastragenol Derivatives Improve Tyrosine Metabolism, Regulate TLR4/NF‐κB/TERT Signaling Pathways, and Inhibit MPTP Induced Neuroinflammation and PD Symptoms

CNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.
Cycloastragenol derivatives regulate the TLR4/NF‐κB/TERT signaling pathway and tyrosine metabolism, breaking the vicious cycle of “inflammation‐aging” and improving symptoms of Parkinson's disease. This study provides direction for the application of natural products in the development of PD drugs.
Shengnan Xiao, Lianmei Liu, Xuemei Qin, Lei Xu, Zhenyu Li, Zhi Chai   +5 more
wiley   +1 more source