This work enhances the antioxidant and antitumor effects of phytocompounds, such as betulinic acid (BA) and taraxerol (TA), using a co‐loaded PCL nanoparticle (NP) system. Results show synergistic effects when BA and TA are co‐encapsulated, indicating PCL nanocarriers could be a promising platform for cancer therapies and other medical uses.
Cyril Tlou Selepe +8 more
wiley +1 more source
A chromosome-level genome assembly reveals triterpenoid biosynthesis in Clinopodium chinense. [PDF]
Li G +8 more
europepmc +1 more source
Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions
Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian +8 more
wiley +1 more source
High‐Throughput Screen of NPQ in Sorghum Shows Highly Polygenic Architecture of Photoprotection
ABSTRACT Natural genetic variation in photosynthesis and photoprotection within crop germplasm represents an untapped resource for crop improvement. Sorghum bicolor (sorghum) is one of the world's most widely grown crops, yet the genetic basis of photoprotection in sorghum is not well understood.
Richard L. Vath +9 more
wiley +1 more source
Comprehensive Identification and Abscisic Acid-Responsive Expression Profiling of NAC Transcription Factor in Triterpenoid Saponin in <i>Hedera helix</i>. [PDF]
Deng X +5 more
europepmc +1 more source
ABSTRACT This study investigates the foliar secondary metabolite profiles of four Mitragyna species naturally occurring in Thailand: M. diversifolia, M. hirsuta, M. rotundifolia, and M. speciosa (kratom). Using untargeted gas chromatography–mass spectrometry (GC–MS), 409 secondary volatile metabolites were annotated across the four species.
Tushar Andriyas +5 more
wiley +1 more source
Aster pekinensis Extract Mitigates High-Fat-Diet-Induced Obesity and Metabolic Dysfunction in Mice. [PDF]
Moon HJ +4 more
europepmc +1 more source
Resistance to Plutella xylostella in collard greens is mediated by antixenosis and antibiosis, associated with traits such as leaf wax, hardness, and color. Genotypes showed strong resistance potential, supporting their use in breeding and integrated pest management strategies. Abstract BACKGROUND The diamondback moth, Plutella xylostella (Lepidoptera:
Aline Marques Pinheiro +6 more
wiley +1 more source
Metabolic engineering of Phaeodactylum tricornutum for heterologous production of the plant triterpenoid friedelin. [PDF]
Nguyen K, Choi MS, Seo S, Song J, Jin E.
europepmc +1 more source
Synthetic Oleanane Triterpenoids Reduce Tumor Growth and Promote an Anti-Tumor Immune Response Independent of Cancer <i>KEAP1</i> Mutational Status. [PDF]
Occhiuto CJ +3 more
europepmc +1 more source

