Results 91 to 100 of about 48,595 (229)

Four New Triterpenoids from Callicarpa kwangtungensis

Molecules, 2015
Four new triterpenoids which were identifed as 2α,3β,6β,19α-tetrahydroxy- oleanolic acid 28-O-β-D-glucopyranoside (1), 2-O-β-D-glucopyranosyloxy-3α,19α-di-hydroxyoleanolic acid (2), 2-O-β-D-glucopyranosyloxy-3α,19α-dihydroxyursolic acid (3), 2α,3α,6β,19α-
Guo-Ping Zhou, Yan Yu, Ming-Ming Yuan, Tengfei Ji, Hui-Zheng Fu, Rui-Jian Zhong   +5 more
doaj   +1 more source

Boosting the biosynthesis of betulinic acid and related triterpenoids in Yarrowia lipolytica via multimodular metabolic engineering

Microbial Cell Factories, 2019
BackgroundBetulinic acid is a pentacyclic lupane-type triterpenoid and a potential antiviral and antitumor drug, but the amount of betulinic acid in plants is low and cannot meet the demand for this compound.
Cong-Cong Jin, Jin-lai Zhang, Hao Song, Yingxiu Cao   +3 more
semanticscholar   +1 more source

Betulin Protects Against Cardiac Hypertrophy by Improving AMPK/Nrf2‐Dependent Mitochondrial Function

Phytotherapy Research, EarlyView.
Betulin effectively mitigates pressure overload‐induced cardiac hypertrophy in both Ang II‐infused and TAC‐operated mice. Mechanistically, betulin activated AMPK phosphorylation, promoted Nrf2 nuclear translocation, and upregulated antioxidant genes (HO‐1 and NQO‐1), thereby restoring mitochondrial function in cardiomyocytes.
Bei Zheng, Mingyang He, Haiying Wu, Tianjie Zhang, Yuxia Jiang, Chuanwei Xin, Meiling Zhang, Jiaqi He, Lulu Zheng   +8 more
wiley   +1 more source

Triterpenoids from Cyclocarya paliurus: structure, biosynthesis, biological activities

Food Science and Human Wellness
Cyclocarya paliurus (Batalin) Iljinskaja, as a unique and rare monocotyledonous plant in Southern China, is a promising and economical Chinese herbal medicine and functional food. People have conducted a number of research on C.
Huiting Xi, Zhongwei Liu, Weixiang Xu, Jiexue Zhao, Yuanxing Wang, Jianhua Xie   +5 more
doaj   +1 more source

Quality Difference Study of 6 Varieties of Ganoderma Lucidum with Different Origins

Frontiers in Pharmacology, 2012
The quality difference of 6 varieties Ganoderma Lucidum with different origins was investigated in this study by comparing the contents of ganoderic acid A and B, polysaccharide and triterpenoids .The contents of ganoderic acid A and B in G.lucidum were ...
Juan eLu, Jia-zhang eQin, Ping eChen, Xi eChen, Ying-Zhi eZhang, Si-jia eZhao   +5 more
doaj   +1 more source

Integrating mass spectrometry and systems biology for the modernization of natural medicines: From deciphering chemical complexity to holistic efficacy assessment

VIEW, EarlyView.
This review explores how mass spectrometry is transforming research in natural medicines, with Traditional Chinese medicine (TCM) as a primary exemplar. It details the application of advanced mass spectrometry in chemical analysis, the development of comprehensive quality control methods, and systematic research on the targeted mechanisms of single ...
Yudian Xu, Linlin Cao, Chenhuan Ding, Chen Wang, Yi Lai, Dan Ru, He Li, Wei Xu   +7 more
wiley   +1 more source

Optimization of triterpenoids biosynthesis in Athelia termitophila as a source of natural products

AMB Express
Triterpenoids exhibit considerable potential and are extensively utilized in both food and pharmaceutical industries. However, Athelia termitophila (TMB) naturally harbors only trace amounts of these compounds. Consequently, this study sought to optimize
Fangcheng Hu, Yonggang Fang, Zahid Khan, Lianxi Xing   +3 more
doaj   +1 more source

Synthesis and Cytotoxicity Evaluation of DOTA-Conjugates of Ursolic Acid

Molecules, 2019
In this study, we report the synthesis of several amine-spacered conjugates of ursolic acid (UA) and 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA).
Michael Kahnt, Sophie Hoenke, Lucie Fischer, Ahmed Al-Harrasi, René Csuk   +4 more
doaj   +1 more source

Characterization and Quantification of Polyphenols and Triterpenoids in Thinned Young Fruits of Ten Pear Varieties by UPLC-Q TRAP-MS/MS

Molecules, 2019
Large quantities of thinned young pears, a natural source of bioactive compounds, are abandoned as agricultural by-products in many orchards. Hence, ten thinned young pear varieties were systematically investigated in terms of their chemical composition ...
Liqiong Sun, S. Tao, Shaoling Zhang
semanticscholar   +1 more source

Fecal Steroids as Tracers of Human Population and Waste Management Practices at the Ancient Maya City of Ucanal, Guatemala

Archaeometry, EarlyView.
ABSTRACT Geochemical data compiled from dried sediments from three water reservoirs at the ancient Maya city of Ucanal, Petén, Guatemala, reveal low to undetectable fecal biomarker concentrations. These low concentrations may be the result of the aerobic decay of sterols combined with well‐managed waste disposal practices.
Jean D. Tremblay, Peter M. J. Douglas, Christina T. Halperin, Yves Gélinas   +3 more
wiley   +1 more source