Results 101 to 110 of about 48,595 (229)
FoodsBioactive compounds have drawn much attention according to their various health benefits. However, poor dissolvability, low stability and limited bioavailability largely narrow their applications.
Wendi Teng +3 more
doaj +1 more source
A-Ring-Modified Triterpenoids and Their Spermidine–Aldimines with Strong Antibacterial Activity
Molbank, 2019 Synthesis of A-ring-modified lupane, oleanane and ursane type triterpenoid conjugates with spermidine through an aldimine linkage or diethylentriamine via an amide bond is described.
Oxana B. Kazakova +6 more
doaj +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Phytochemical Study of Aerial Parts of Leea asiatica
Molecules, 2019 Leea asiatica (L.) Ridsdale (Leeaceae) is found in tropical and subtropical countries and has historically been used as a traditional medicine in local healthcare systems. Although L.
Hyun Woo Kil +2 more
doaj +1 more source
Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt
British Journal of Pharmacology, EarlyView.Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown +2 more
wiley +1 more source
Química Nova, 2005 The chemical study of the propolis produced in Teresina city, state of Piaui, resulted in the identification of six cycloartane triterpenoids: isomangiferolic acid, 24-methylenecycloartane-3beta,26-diol, mangiferolic acid, mangiferonic acid, ambonic acid
Maria do Socorro Sousa da Silva +3 more
doaj +1 more source
The multidimensional regulation roles and mechanisms of calcium in fruit quality
Journal of Integrative Plant Biology, EarlyView.This review explores how calcium signaling molecule integrates plant hormones, environmental cues, and developmental signals to influence external fruit traits, internal nutritional properties, and physiological disorders. ABSTRACT Calcium (Ca2+), a dual‐functional mineral that serves both as an essential structural factor and a signaling molecule ...
Fei Jiang +6 more
wiley +1 more source
Acta Societatis Botanicorum Poloniae, 2017 Edible honeysuckle (honeyberry) Lonicera caerulea is becoming popular as a novel berry crop with several useful features such as early fruit ripening and exceptional hardiness, particularly resistance to pests and diseases as well as severe frosts in ...
Rafał Becker +2 more
doaj +1 more source
Rewiring Steroidal Metabolic Pathways for Diosgenin Production in Solanum nigrum
Plant Biotechnology Journal, EarlyView.ABSTRACT Diosgenin is a key starting material for the synthesis of steroidal drugs, such as corticosteroids and sex hormones. While the primary commercial source of diosgenin is the tubers of Dioscorea spp., identifying alternative plant hosts capable of diosgenin biosynthesis could enhance its production.
Jongbu Lim +16 more
wiley +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT Mango (Mangifera indica) is one of the most popular fruits cultivated in tropical and subtropical regions of the world. The availability of reference genomes helps to identify the genetic basis of important traits. Here, we report assembled high‐quality chromosome‐level genomes for the Australian mango cultivar ‘Kensington Pride’ and M ...
Upendra Kumari Wijesundara +5 more
wiley +1 more source