Results 151 to 160 of about 30,032 (223)

Bio‐guided fractionation of (9Z )‐5,8,11‐trihydroxyoctadec‐9‐enoic acid from Abelmoschus sagittifolius root as a potent α‐glucosidase inhibitor: An integrated in vitro and in silico study

open access: yesJournal of the Science of Food and Agriculture, Volume 106, Issue 13, Page 7735-7746, October 2026.
Abstract BACKGROUND Abelmoschus sagittifolius stands out as a valuable medicinal source for developing functional food targeting type 2 diabetes. This study investigated the α‐glucosidase inhibitory potential of an active fraction obtained from A. sagittifolius roots (ASR), enriched in (9Z)‐5,8,11‐trihydroxyoctadec‐9‐enoic acid (OA), using both enzyme ...
Nguyen Phuong Mai   +3 more
wiley   +1 more source

The Mycorrhizal Fungal Species Funneliformis mosseae Reshapes Rhizosphere Microbial Metabolic Pathways of Soybeans Under Tetracycline Stress

open access: yesMicrobiologyOpen, Volume 15, Issue 5, October 2026.
The presence of residual antibiotics (tetracycline) poses a threat to food safety in the black soils of northeastern China and a mycorrhizal fungal species Funneliformis mosseae could mitigate the negative effects. This study tracked the changes in soybeans' rhizospheric microbial profiles and the associated metabolites during the bioremediation ...
Chao Yang   +6 more
wiley   +1 more source

Adjuvant Antibacterial Effects of Mouriri Elliptica Against Clinical Multidrug Resistant Gram‐Negative Bacterial Strains

open access: yesMicrobiologyOpen, Volume 15, Issue 5, October 2026.
The ethanolic leaf extract of Mouriri elliptica exhibited antibacterial and antibiofilm activities against multidrug‐resistant clinical isolates and enhanced the activity of ampicillin. Its diverse chemical profile and low acute toxicity support this Cerrado species as a promising source of natural antibacterial adjuvants. ABSTRACT Bacterial resistance
Talita Vilalva Freire   +9 more
wiley   +1 more source

Dual Antiviral and Immunomodulatory Effects of Phytochemicals in Influenza A Virus Infection: Targeting Key Host Signaling Pathways

open access: yesMicrobiologyOpen, Volume 15, Issue 5, October 2026.
Influenza A virus modulates host innate immune pathways, including TLR, RIG‐I, MAPK, and NF‐κB signaling, to support replication and drive inflammatory pathology. Plant‐derived phytocompounds target these interconnected pathways, offering a potential host‐directed immunomodulatory approach complementary to conventional antivirals.
Dibakar Chowdhury   +3 more
wiley   +1 more source

Aspergillus niger as a New Endophytic Fungus From Deverra tortuosa: Phytochemical Profile, Molecular Docking, Antimicrobial, Antibiofilm, Antioxidant, and Anticancer Activities

open access: yesMicrobiologyOpen, Volume 15, Issue 5, October 2026.
Aspergillus niger AA1 isolated from Deverra tortuosa produced a metabolite‐rich extract with antibacterial, antibiofilm, antioxidant, and selective anticancer activities. Gas chromatography–mass spectrometry identified major bioactive compounds, while molecular docking supported their interactions with DNA gyrase B and estrogen receptor alpha ...
Samy Selim   +10 more
wiley   +1 more source

Tripterine Liposome Exerts Antitumor and Immunomodulatory Effects in Pancreatic Ductal Adenocarcinoma

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Tripterine liposome (TP‐lipo) exerts anti‐pancreatic ductal adenocarcinoma (PDAC) effects through direct suppression of tumor cells and modulation of the tumor microenvironment (TME). TP‐lipo induces apoptosis and inhibits the clonogenicity, migration, and invasion of KPC cells in vitro.
Lirui Tang   +8 more
wiley   +1 more source

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