Results 161 to 170 of about 30,032 (223)

Comprehensive Bioactivity-Guided Isolation, DeepSAT, and LC-Q-TOF-MS/MS Analysis to Reveal Hypoglycemic Constituents of Momordica charantia L. [PDF]

J Food Sci
Lv HW, Fan WL, Shi RH, Emam M, Wang H, Zhu MD, Li XN.   +6 more
europepmc   +1 more source

Elucidating the MultiPathway Therapeutic Potential of Trichosanthes kirilowii Bioactives in Intestinal Obstruction via Network Pharmacology and Molecular Dynamics

ChemistryOpen, Volume 15, Issue 10, October 2026.
Network pharmacology identifies 31 shared targets linking T. kirilowii bioactives to intestinal obstruction, highlighting TNF, PI3K‐Akt, and MAPK signaling. Comparative docking, validation, and 100 ns molecular dynamics with MM/GBSA nominate β‐D‐glucopyranosyl‐α‐spinasterol as the leading candidate, binding albumin with the strongest predicted affinity
Tianying Wu, Xiaofen Lin, Wencong Lin, Lixia Huang, Yuewu Lin   +4 more
wiley   +1 more source

Glycyrrhizin (GLY) and glycyrrhetinic acid (GA) as potential multi-target antimicrobials: mechanisms, biofilm disruption, and synergy against drug-resistant pathogens. [PDF]

Front Microbiol
Gahlot KD.
europepmc   +1 more source

The Bile Acid Signaling Axis: Deciphering the Roles of FXR and TGR5 in Hepatic Steatosis, Fibrosis, and Cancer

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT Bile acids (BAs) serve not only as emulsifiers for lipid digestion but also as essential signaling molecules, governing various physiological and pathological processes through their interaction with the farnesoid X receptor (FXR) and the takeda G protein‐coupled receptor 5 (TGR5).
Jie Liu, Kui Sun, Hongmei Liu, Meiyang Zhu, Chunmeng Li, Yuqi He, Lin Qin   +6 more
wiley   +1 more source

Research Progress on Pharmacological Effects of Key Pharmacodynamic Material Basis Components of <i>Schisandrae chinensis</i> Fructus. [PDF]

J Microbiol Biotechnol
Pan H, Yu H, Liu R, Zhou L, Wang Z, Liu Q, Wang G.   +6 more
europepmc   +1 more source

Almond Shell‐Derived Cellulosic Microfibres: Extraction, Characterisation and Applications in Sustainable Paper‐Based Packaging

Packaging Technology and Science, Volume 39, Issue 10, Page 1231-1251, October 2026.
Cellulosic microfibres were extracted from almond shells using organosolv, soda and kraft processes, and comprehensive physicochemical, surface, thermal and morphological characterisation demonstrated their strong potential as sustainable fillers for paper‐based packaging application. ABSTRACT This study develops pathways for the valorisation of almond
Lokesh Kumar, Sachin Agate, T. Edwin Freeman, Preeti Tyagi, Lokendra Pal   +4 more
wiley   +1 more source

Amphiphilic Semisynthetic Triterpenoids Impair Survival Pathways and Suppress Clonogenic Growth in Multidrug-Resistant High-Risk Neuroblastoma. [PDF]

Int J Mol Sci
Alfei S, Domenicotti C, Tirendi S, Khaledizadeh E, Graikioti D, Athanassopoulos CM, Zuccari G, Reggio C, Marengo B.   +8 more
europepmc   +1 more source

Peroxiredoxin 4 Involved in Spermatogenesis by Affecting Oxidative Stress and Ferroptosis

Andrology, Volume 14, Issue 7, Page 2329-2346, October 2026.
ABSTRACT Background The main functions of testes are sperm production and androgen secretion in testicular befitting microenvironment. Excessive level of the reactive oxygen species (ROS) from metabolism and cellular events can lead to oxidative stress (OS) and ferroptosis, which injure the functions of mitochondria and endoplasmic reticulum (ER) of ...
Shuning Yuan, Nini Wei, Weiwei Ma, Mengting Hu, Bei Zhang, Li Gao, Chao Gao, Xiaoyu Yang, Yan Meng, Jiayin Liu, Yugui Cui   +10 more
wiley   +1 more source

Bioactive Compounds from Edible and Medicinal Mushrooms in Obesity-Depression Comorbidity: Gut-Brain Axis Mechanisms and Functional Food Perspectives. [PDF]

Foods
Li W, Chi D, Hu X, Liu Y, Li Z, Li Y, Dai Y, Li Y.   +7 more
europepmc   +1 more source

Glucuronyl Glucosyloleanolate: A Safe and Potent AI‐Discovered Depigmenting Saponin

Journal of Cosmetic Dermatology, Volume 25, Issue 10, October 2026.
ABSTRACT Purpose Saponins are amphiphilic glycosides found in plants. They have long been used in traditional Asian remedies for their anti‐inflammatory, protective, and rejuvenating properties. One representative, Glucuronyl Glucosyloleanolate (GGO), was recently discovered using a combination of artificial intelligence and experimental testing as a ...
Yannick Quesnel, Michael Gold
wiley   +1 more source