Results 221 to 230 of about 115,594 (235)

Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment

Advanced Science, EarlyView.
Liver metastasis diverts aspartate into hyperactive pyrimidine synthesis, disrupting urea cycling and causing pathogenic ammonia accumulation. Ammonia dually reprograms the microenvironment by: (1) activating hepatic stellate cells (HSCs) into pro‐fibrotic metastasis‐associated fibroblasts (MAFs), and (2) suppressing anti‐tumor monocytes/macrophages ...
Sumin Sun, Haili Hu, Long Chen, Yuan Gao, Peng Sun, Liming Chen   +5 more
wiley   +1 more source

Hepatic Expression of Growth Hormone Receptor (<i>GHrec</i>) and Insulin-like Growth Factor-I (<i>IGF-I</i>) Genes and Cellular Location of <i>IGF-I</i> mRNA in Diploid and Triploid Atlantic Salmon (<i>Salmo salar</i>) Undergoing Parr-Smolt Transformation. [PDF]

Animals (Basel)
Bortoletti M, Fonsatti E, Maccatrozzo L, Peruzzi S, Jobling M, Vascellari M, Radaelli G, Bertotto D.   +7 more
europepmc   +1 more source

Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis

Advanced Science, EarlyView.
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu, Yaqian Cui, Yongqiang Zhou, Yihui Zheng, Lijiang Huang, Leiming Jin, Qianhui Zhang, Pan Chen, Mengsha Lin, Jiaxi Ye, Yongqiang Xiong, Joo Young Huh, Xiang Hu, Xiaokun Li, Wu Luo, Guang Liang   +15 more
wiley   +1 more source

Liofilização como método de conservação de RNA. [PDF]

, 2011
IBELLI, A. M. G., REGITANO, L. C. de A., SOUZA, J. R. T. de   +2 more
core  

A robust absolute quantification protocol for potato virus Y based on reverse transcription-quantitative PCR. [PDF]

MicroPubl Biol
Spencer D, Padilla-Crespo E, Tan EH.
europepmc   +1 more source

Dynamics of antiretroviral restriction factor expression in sheep naturally infected with Small ruminant lentivirus (SRLV). [PDF]

Arch Virol
Rodríguez-Murillo C, González-Fernández VD, Castillo-Hernández G, Akbarin MM, Álvarez HR.   +4 more
europepmc   +1 more source

Local Delivery of Genistein in Peri-Implant Defects Enhances Osseointegration in Ovariectomized Rats. [PDF]

Calcif Tissue Int
Duarte ND, de Souza Batista FR, Gomes MB, Macedo LG, Monteiro NG, Mulinari-Santos G, Gomes-Ferreira PHS, Lisboa-Filho PN, Meirelles L, Okamoto R.   +9 more
europepmc   +1 more source

Construction and characterization of the ORF131 gene deletion strain of lumpy skin disease virus. [PDF]

Virol J
Li J, Huang W, Ke Q, Li M, Wang X, Wang Q, Yin X, Sun Y.   +7 more
europepmc   +1 more source