Role of neurotrophins on dermal fibroblast survival and differentiation [PDF]
Neurotrophins (NTs) belong to a family of growth factors that play a critical role in the control of skin homeostasis. NTs act through the low-affinity receptor p75NTR and the high-affinity receptors TrkA, TrkB and TrkC.
Dallaglio, Katiuscia +9 more
core +3 more sources
Microarray Analysis Reveals Increased Transcriptional Repression and Reduced Metabolic Activity but Not Major Changes in the Core Apoptotic Machinery during Maturation of Sympathetic Neurons [PDF]
Postnatal maturation of the neurons whose main phenotype and basic synaptic contacts are already established includes neuronal growth, refinement of synaptic contacts, final steps of differentiation, programmed cell death period (PCD) etc.
Jaan ePalgi +4 more
core +1 more source
Investigating the changes of hippocampal m-RNA gene expression of neurotrophin-3 and its receptor (Tropomyosin Receptor Kinase C) in the recovery of movements of rats with spinal cord injury during two types of endurance exercises [PDF]
Background: This study aimed to investigate the effect of four weeks of selected endurance training on neurotrophin-3 (NT-3) and tropomyosin receptor kinase C (TrkC) gene expression in hippocampal areas of rats with spinal cord injury (SCI).
Sina Jalili Rasti +3 more
doaj
SALM5 trans-synaptically interacts with LAR-RPTPs in a splicing-dependent manner to regulate synapse development [PDF]
Synaptogenic adhesion molecules play critical roles in synapse formation. SALM5/Lrfn5, a SALM/Lrfn family adhesion molecule implicated in autism spectrum disorders (ASDs) and schizophrenia, induces presynaptic differentiation in contacting axons, but its
Cho, Kwangwook +15 more
core +2 more sources
Transcriptional regulation of TRKC by SOX2 in human embryonic stem cells
Human embryonic stem (hES) cells have the dual ability to self-renew and differentiate into specialized cell types. However, in order to realize the full potential of these cells it is important to understand how the genes responsible for their unique characteristics are regulated.
Fong, Helen +2 more
openaire +2 more sources
In previous neural tissue engineering studies, we successfully constructed NT-3 cross-linked acellular spinal cord scaffolds (NT-3 cross-linked scaffolds), which can sustain the release of NT-3 and promote the differentiation of rat bone marrow ...
Tao Jiang +4 more
doaj +1 more source
Neurotrophin receptors expression and JNK pathway activation in human astrocytomas
Background Neurotrophins are growth factors that regulate cell growth, differentiation and apoptosis in the nervous system. Their diverse actions are mediated through two different transmembrane – receptor signaling systems: Trk receptor tyrosine kinases
Maraziotis Theodore +4 more
doaj +1 more source
High Resolution Mapping of the Binding Site of TrkA for Nerve Growth Factor and TrkC for Neurotrophin-3 on the Second Immunoglobulin-like Domain of the Trk Receptors [PDF]
Roman Urfer +5 more
openalex +1 more source
A neuronal subpopulation in the mammalian enteric nervous system expresses TrkA and TrkC neurotrophin receptor-like proteins [PDF]
I. Esteban +6 more
openalex +1 more source
Srsf1 and Elavl1 act antagonistically on neuronal fate choice in the developing neocortex by controlling TrkC receptor isoform expression [PDF]
A Ioana Weber +12 more
openalex +1 more source

