Novel spiroisatin-pyranopyrazole hybrids as anticancer agents with TrkC inhibitory potential
Cancer still represents a global health concern due to its high mortality and morbidity rates. Isatin-and pyrazole-based compounds have recently garnered interest as novel anticancer agents. A series of 15 novel spiroisatin pyranopyrazole derivatives were synthesized.
Somayeh, Mohammadi +6 more
openaire +2 more sources
TrkC kinase expression in distinct subsets of cutaneous trigeminal innervation and nonneuronal cells
Ursula Fünfschilling +5 more
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Evaluation of <i>NTRK</i> Fusions Detection Method in Esophageal Squamous Cell Carcinoma and Gastric Adenocarcinoma. [PDF]
Momma T +14 more
europepmc +1 more source
Current State of the Neurotrophin-Based Pharmaceutics in the Treatment of Neurodegenerative Diseases and Neuroinflammation. [PDF]
Fedotcheva TA, Shimanovsky NL.
europepmc +1 more source
Trypanosoma cruziPromotes Neuronal and Glial Cell Survival through the Neurotrophic Receptor TrkC
Craig Weinkauf, Mercio PereiraPerrin
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Developing Schwann cells acquire the ability to survive without axons by establishing an autocrine circuit involving IGF, NT-3 and PDGF-BB [PDF]
Brennan, A +4 more
core
NT3/TrkC pathway modulates the expression of UCP-1 and adipocyte size in human and murine adipose tissue [PDF]
María Bové +12 more
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TrkA Expression as a Novel Prognostic Biomarker in Oral Squamous Cell Carcinoma. [PDF]
Ciarka A +8 more
europepmc +1 more source
Role of TRKC and NT-3 proteins in the progression and prognosis of colorectal cancer. [PDF]
Chen S +8 more
europepmc +1 more source
Selective Modulation of Trk Receptors by <i>Cyclo</i>-Organopeptides. [PDF]
Joy S +7 more
europepmc +1 more source

