Results 51 to 60 of about 10,654 (244)
Construction of functional neural network tissue combining CBD-NT3-modified linear-ordered collagen scaffold and TrkC-modified iPSC-derived neural stem cells for spinal cord injury repair. [PDF]
Bioact MaterWu Z +18 more
europepmc +2 more sources
Deletion of Tsc2 in nociceptors reduces target innervation, ion channel expression, and sensitivity to heat [PDF]
, 2018 The mechanistic target of rapamycin complex 1 (mTORC1) is known to regulate cellular growth pathways, and its genetic activation is sufficient to enhance regenerative axon growth following injury to the central or peripheral nervous systems.
Carlin, Dan +6 more
core +2 more sources
Cell Transplantation, 2013 Our previous study indicated that electroacupuncture (EA) could increase neurotrophin-3 (NT-3) levels in the injured spinal cord, stimulate the differentiation of transplanted bone marrow mesenchymal stem cells (MSCs), and improve functional recovery in ...
Ying Ding +11 more
doaj +1 more source
Clinical and molecular features and therapeutic perspectives of spinal muscular atrophy with respiratory distress type 1 [PDF]
, 2015 Spinal muscular atrophy with respiratory distress (SMARD1) is an autosomal recessive neuromuscular disease caused by mutations in the IGHMBP2 gene, encoding the immunoglobulin μ-binding protein 2, leading to motor neuron degeneration.
Corti, Stefania +4 more
core +2 more sources
Folia Medica, 2015 ВВЕДЕНИЕ: Модель шизофрении, связанной с нарушениями в развитии постулирует патологические отклонения в эмбриональном нейрогенезе в качестве этиопатогенетической основы шизофренических психозов.
Koeva Yvetta A. +2 more
doaj +1 more source
Dependence receptor TrkC is a putative colon cancer tumor suppressor [PDF]
Proceedings of the National Academy of Sciences, 2013 The TrkC neurotrophin receptor belongs to the functional dependence receptor family, members of which share the ability to induce apoptosis in the absence of their ligands. Such a trait has been hypothesized to confer tumor-suppressor activity. Indeed, cells that express these receptors are thought to be dependent on ligand availability for their ...
Genevois, A.-L. +12 more
openaire +2 more sources
Functional Diversity of Neurotrophin Actions on the Oculomotor System [PDF]
, 2016 Neurotrophins play a principal role in neuronal survival and differentiation during development, but also in the maintenance of appropriate adult neuronal circuits and phenotypes.
Benítez Temiño, Beatriz +5 more
core +1 more source
Neurobiology of Disease, 2006 Accumulating evidence has suggested that neurotrophins participate in the pathophysiology of mood disorders. We have developed transgenic mice overexpressing the full-length neurotrophin-3 receptor TrkC (TgNTRK3) in the central nervous system.
Mara Dierssen +18 more
doaj +1 more source
Modulation of neurotrophic signaling pathways by polyphenols [PDF]
, 2015 Polyphenols are an important class of phytochemicals, and several lines of evidence have demonstrated their beneficial effects in the context of a number of pathologies including neurodegenerative disorders such as Alzheimer's and Parkinson's disease. In
Firuzi, Omidreza +3 more
core +1 more source
Complexes of Discrete Distributional Differential Forms and their Homology Theory [PDF]
, 2015 Complexes of discrete distributional differential forms are introduced into finite element exterior calculus. Thus we generalize a notion of Braess and Sch\"oberl, originally studied for a posteriori error estimation.
Licht, Martin Werner
core +1 more source