Results 61 to 70 of about 10,654 (244)
Single-cell RNAseq reveals seven classes of colonic sensory neuron. [PDF]
, 2018 OBJECTIVE: Integration of nutritional, microbial and inflammatory events along the gut-brain axis can alter bowel physiology and organism behaviour. Colonic sensory neurons activate reflex pathways and give rise to conscious sensation, but the diversity ...
Bach, Karsten +9 more
core +1 more source
Cells, 2019 Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide and often has a poor prognosis. The present study investigated the role of the low affinity nerve growth factor receptor CD271 as a putative therapy target in HNSCC ...
Yannick Foerster +7 more
doaj +1 more source
REST/NRSF Knockdown Alters Survival, Lineage Differentiation and Signaling in Human Embryonic Stem Cells. [PDF]
, 2015 REST (RE1 silencing transcription factor), also known as NRSF (neuron-restrictive silencer factor), is a well-known transcriptional repressor of neural genes in non-neural tissues and stem cells.
Jan, Majib +4 more
core +3 more sources
Structural basis for extracellular cis and trans RPTPσ signal competition in synaptogenesis [PDF]
, 2014 Receptor protein tyrosine phosphatase sigma (RPTPσ) regulates neuronal extension and acts as a presynaptic nexus for multiple protein and proteoglycan interactions during synaptogenesis.
Aricescu, AR +9 more
core +2 more sources
Co-cultures with stem cell-derived human sensory neurons reveal regulators of peripheral myelination [PDF]
, 2017 Effective bidirectional signalling between axons and Schwann cells is essential for both the development and maintenance of peripheral nerve function. We have established conditions by which human induced pluripotent stem cell-derived sensory neurons can
Bennett, David L.H. +5 more
core +2 more sources
Cell Transplantation, 2002 Although CNS axons have the capacity to regenerate after spinal cord injury when provided with a permissive substrate, the lack of appropriate synaptic target sites for regenerating fibers may limit restoration of spinal circuitry.
Daniel A. Castellanos +5 more
doaj +1 more source
Computational and Systems Oncology, Volume 6, Issue 1, December 2026.ABSTRACT Resistance to chemotherapy, which is demonstrated in almost every patient with advanced‐stage lung cancer (ALC), underscores an urgent need to unravel the underlying molecular mechanisms and identify novel strategies to overcome drug resistance. In the present study, an attempt was made to identify epigenetic targets and modulators that can be
Okibur Rahman +2 more
wiley +1 more source
Serum Level Changes of Neurotrophin-3 After Performing Diabetic Foot Exercise in Diabetic Neuropathy [PDF]
, 2015 The research aimed to determine the pattern of changes in serum levels of NT-3 in the improvement of diabetic neuropathy, after doing diabetic foot exercise. A true experimental study with randomaized pre – post test control trial. A total of 36 subjects
Pranoto, A. (Agung) +2 more
core +3 more sources
Neurotrophins and neurotrophin receptors in proliferative diabetic retinopathy. [PDF]
PLoS ONE, 2013 Neurotrophins (NTs) are emerging as important mediators of angiogenesis and fibrosis. We investigated the expression of the NTs nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4) and ...
Ahmed M Abu El-Asrar +8 more
doaj +1 more source
MedComm, Volume 7, Issue 2, February 2026.Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source