Results 81 to 90 of about 10,654 (244)
Runx1 selectively regulates cell fate specification and axonal projections of dorsal root ganglion neurons [PDF]
"平成18年度""2006"--CoverAbstract in JapaneseThesis (Ph. D. in Neuroscience)--University of Tsukuba, (A), no.
吉川 雅朗
core +1 more source
New, potent, small molecule agonists of tyrosine kinase receptors attenuate dry eye disease
Nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and neurotrophin3 (NT-3) bind to tyrosine kinase (Trk) receptors, TrkA, TrkB, and TrkC, respectively. This study investigated the efficacy of novel molecule agonists of Trk receptors in
Zhiyuan Yu +5 more
doaj +1 more source
Expression and prognostic impact of NTF3 and TrkC in hepatocellular carcinoma
Treatment of patients with NTRK fusion-positive cancers using first-generation tropomyosin-related kinase (Trk) inhibitors is associated with high response rates, regardless of tumor histology. However, there have been few studies on neurotrophin-3 (NTF3) and TrkC ligands in hepatocellular carcinoma (HCC).
Hejing, Wang +4 more
openaire +2 more sources
Background It was important to find better therapeutic drugs for idiopathic pulmonary fibrosis (IPF), and in our previous study, Yifei decoction (YFT) alleviated IPF. A deeper understanding of its mechanisms of action could aid in the development of novel treatment strategies.
Lijuan Chen +9 more
wiley +1 more source
Early specification of sensory neuron fate revealed by expression and function of neurogenins in the chick embryo [PDF]
The generation of sensory and autonomic neurons from the neural crest requires the functions of two classes of basic helix-loop-helix (bHLH) transcription factors, the Neurogenins (NGNs) and MASH-1, respectively (Fode, C., Gradwohl, G., Morin, X ...
Anderson, David J. +2 more
core
The transcription factor Brn3a, product of the pou4f1 gene, is expressed in most sensory neurons throughout embryogenesis. Prior work has demonstrated a role for Brn3a in the repression of early neurogenic genes; here we describe a second major role for ...
Raisa Eng S +3 more
doaj +1 more source
ABSTRACT Sensory neuron disorders, such as peripheral neuropathies and trigeminal neuralgia, cause chronic pain and sensory dysfunction; however, regenerative treatments are limited. Human pluripotent stem cells (hPSCs) provide a powerful platform to model these diseases by generating functional sensory neuron subtypes, including nociceptors and ...
Pushpanathan Muthuirulan +3 more
wiley +1 more source
Propioceptores articulares y musculares [PDF]
La función de los mecanorreceptores de las articulaciones y músculos se considera asociada a la propiocepción. Sin embargo, existen evidencias de que la propiocepción no sólo depende del morfotipo de mecanorreceptor presente en dichos tejidos sino ...
Vega, José A.
core +2 more sources
Background Arsenic trioxide (As2O3), a drug that has been used in China for approximately two thousand years, induces cell death in a variety of cancer cell types, including neuroblastoma (NB).
Xilin Xiong +6 more
doaj +1 more source
Characteristics of sensory neuronal groups in CGRP-cre-ER reporter mice: Comparison to Nav1.8-cre, TRPV1-cre and TRPV1-GFP mouse lines. [PDF]
Peptidergic sensory neurons play a critical role in nociceptive pathways. To precisely define the function and plasticity of sensory neurons in detail, new tools such as transgenic mouse models are needed.
Mayur J Patil +2 more
doaj +1 more source

