Results 141 to 150 of about 2,313,793 (272)

High Resolution Mapping of the Binding Site of TrkA for Nerve Growth Factor and TrkC for Neurotrophin-3 on the Second Immunoglobulin-like Domain of the Trk Receptors [PDF]

, 1998
Roman Urfer, Pantelis Tsoulfas, Lori O'Connell, Jo-Anne Hongo, Wei Zhao, Leonard G. Presta   +5 more
openalex   +1 more source

Supplementary Methods from TrkC Binds to the Bone Morphogenetic Protein Type II Receptor to Suppress Bone Morphogenetic Protein Signaling [PDF]

, 2023
Wook Jin, Chohee Yun, Hae-Suk Kim, Seong‐Jin Kim   +3 more
openalex   +2 more sources

Inducers of epithelial mesenchymal transition and cancer stem cells in malignant pleural effusions [PDF]

, 2016
The Epithelial to Mesenchymal Transition (EMT) plays a role not only in tumor metastasis but also in tumor recurrence. This process is believed to be tightly linked to the presence of Cancer Stem Cells (CSCs) however, it is still not clear which ...
Cherubini, Emanuela, Giarnieri, Enrico, Giovagnoli, Maria Rosaria, Mancini, Rita, Mariotta, Salvatore, Ricci, Alberto   +5 more
core   +1 more source

A neuronal subpopulation in the mammalian enteric nervous system expresses TrkA and TrkC neurotrophin receptor-like proteins [PDF]

, 1998
I. Esteban, B. Levanti, Olivia García‐Suárez, G. Germanà, E. Ciriaco, F.J. Naves, José A. Vega   +6 more
openalex   +1 more source

The binding epitopes of neurotrophin-3 to its receptors trkC and gp75 and the design of a multifunctional human neurotrophin. [PDF]

, 1994
Roman Urfer, Pantelis Tsoulfas, Dan Soppet, Enrique Escandón, Luis F. Parada, Leonard G. Presta   +5 more
openalex   +1 more source

Neurotrophic tyrosine kinase receptor 1 (NTRK1; TrkA); NTRK2 (TrkB); NTRK3 (TrkC); brain-derived neurotrophic factor (BDNF); nerve growth factor (NGF) [PDF]

, 2009

openalex   +1 more source

Potential effectiveness of Vitrakvi (Larotrectinib) for treating types of solid tumors carrying NTRK genes and the impact of TRKC mutations

La Granja: Revista de Ciencias de la Vida
Vitrakvi is a cancer treatment that targets solid tumors with NTRK gene fusion. NTRKs are rare genetic effects that can arise in tumors from several organs, including the lungs, thyroid glands, and intestines.
Ali Adel Dawood
doaj   +1 more source

Electroacupuncture Promotes the Differentiation of Transplanted Bone Marrow Mesenchymal Stem Cells Preinduced with Neurotrophin-3 and Retinoic Acid into Oligodendrocyte-Like Cells in Demyelinated Spinal Cord of Rats

Cell Transplantation, 2015
Transplantation of bone marrow mesenchymal stem cells (MSCs) promotes functional recovery in multiple sclerosis (MS) patients and in a murine model of MS.
Zhou Liu, Bing He, Rong-Yi Zhang, Ke Zhang, Ying Ding, Jing-Wen Ruan, Eng-Ang Ling, Jin-Lang Wu, Yuan-Shan Zeng M.D., Ph.D.   +8 more
doaj   +1 more source

Cancer immunotherapeutic targeting tropomyosin receptor kinase C (TrkC) through its conjugate and cyclophosphamide

Immunopharmacology and Immunotoxicology
Cancer cells often overexpressed specific receptors to support their proliferation and promote immunosuppressive tumor microenvironment. Tropomyosin receptor kinase C (TrkC) is known to be overexpressed in cancer, and implicated in promoting tumor progression and metastasis.
Siti Nursyahirah Bakar, Lik Voon Kiew, Lip Yong Chung, Kevin Burgess, Chin Siang Kue   +4 more
openaire   +1 more source

Distinct steps of neural induction revealed by Asterix, Obelix and TrkC, genes induced by different signals from the organizer.

PLoS ONE, 2011
The amniote organizer (Hensen's node) can induce a complete nervous system when grafted into a peripheral region of a host embryo. Although BMP inhibition has been implicated in neural induction, non-neural cells cannot respond to BMP antagonists unless ...
Sonia Pinho, Pamela R Simonsson, Katherine E Trevers, Matthew J Stower, William T Sherlock, Mohsin Khan, Andrea Streit, Guojun Sheng, Claudio D Stern   +8 more
doaj   +1 more source